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中华医学超声杂志(电子版) ›› 2018, Vol. 15 ›› Issue (11) : 804 -807. doi: 10.3877/cma.j.issn.1672-6448.2018.11.002

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华支睾吸虫病的多模态超声诊断及病理学机制研究进展
张聪1, 刘千琪1, 田洁1, 吴长君1,()   
  1. 1. 150001 哈尔滨医科大学附属第一医院超声医学科
  • 收稿日期:2018-05-08 出版日期:2018-11-01
  • 通信作者: 吴长君

Research on multimodal ultrasound diagnosis and pathological mechanism of clonorchiasis sinensis

Cong Zhang1, Qianqi Liu1, Jie Tian1   

  • Received:2018-05-08 Published:2018-11-01
引用本文:

张聪, 刘千琪, 田洁, 吴长君. 华支睾吸虫病的多模态超声诊断及病理学机制研究进展[J]. 中华医学超声杂志(电子版), 2018, 15(11): 804-807.

Cong Zhang, Qianqi Liu, Jie Tian. Research on multimodal ultrasound diagnosis and pathological mechanism of clonorchiasis sinensis[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2018, 15(11): 804-807.

图1 华支睾吸虫病常规二维超声声像图。华支睾吸虫病超声表现多起自肝左叶,以肝左叶小胆管增粗为主(箭头所示)
图2 华支睾吸虫对胆道及肝脏的损伤途径示意图。A.机械性损伤:胆管内成虫在摄食和运动过程中对胆管上皮细胞产生机械性损伤B.化学性损伤:①虫体表面和排泄孔释放出来的排泄分泌产物破坏胆管上皮屏障作用;②胆汁消化作用,破溃的胆管难以抵御胆汁中的主要成分(如胆汁酸盐、胆酸等)对胆管上皮的进一步损伤;③胆道菌群紊乱,华支睾吸虫及相应针对性治疗引起胆道及肠道菌群变化
1
Parkin DM. The global health burden of infection-associated cancers in the year 2002 [J]. Int J Cancer, 2006, 118(12): 3030-3044.
2
Lai DH, Hong XK, Su BX, et al. Current status of Clonorchis sinensis and clonorchiasis in China [J]. Trans R Soc Trop Med Hyg, 2016, 110(1): 21-27.
3
Qian MB, Chen YD, Yang YC, et al. Increasing prevalence and intensity of foodborne clonorchiasis, Hengxian County, China, 1989-2011 [J]. Emerg Infect Dis, 2014, 20(11): 1872-1875.
4
Qian MB, Utzinger J, Keiser J, et al. Clonorchiasis [J]. Lancet, 2016, 387(10020): 800-810.
5
McConnell JFP. Remarks on the anatomy and pathological relations of a new species of liver-fluke [J]. Lancet, 1875, 106: 271-274.
6
Feng M, Cheng X. Parasite-associated cancers (blood flukes/liver flukes) [J]. Adv Exp Med Biol, 2017, 1018: 193-205.
7
Lun ZR, Gasser RB, Lai DH, et al. Clonorchiasis: a key foodborne zoonosis in China [J]. Lancet Infect Dis, 2005, 5(1): 31-41.
8
Lim JH. Liver flukes: the Malady neglected [J]. Korean J Radiol, 2011, 12: 269-279.
9
Mairiang E. Ultrasonographic features of hepatobiliary pathology in opisthorchiasis and opisthorchiasis-associated cholangiocarcinoma [J]. Parasitol Int, 2017, 66(4): 378-382.
10
Prueksapanich P, Piyachaturawat P, Aumpansub P, et al. Liver fluke-associated biliary tract cancer [J]. Gut Liver, 2018, 12(3): 236-245.
11
Gouveia MJ, Pakharukova MY, Laha T, et al. Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model [J]. Carcinogenesis, 2017, 38(9): 929-937.
12
Sun Q, Liu X, Hao Y, et al. A misdiagnosis of clonorchiasis as gallstone, leading to an unnecessary cholecystectomy: a case report [J]. Am J Emerg Med, 2014, 32(11): 1442.e3-5.
13
Chen H, Chen S, Huang Z, et al. Relationship between blood parameters and Clonorchis sinensis infection: A retrospective single center study [J]. Int Immunopharmacol, 2018, 59: 120-126.
14
Singh S, Muir AJ, Dieterich DT, et al. American gastroenterological association institute technical review on the role of elastography in chronic liver diseases [J]. Gastroenterology, 2017, 152(6): 1544-1577.
15
Gao Q, Shao D, Pan A, et al. Noninvasive assessment of liver stiffness by transient elastography (FibroScan) in liver fluke disease [J]. Eur J Gastroenterol Hepatol, 2016, 28(1): 70-73.
16
陈颖丹, 诸廷俊, 许隆祺, 等. 《华支睾吸虫病诊断标准》解读[J]. 中国血吸虫病防治杂志, 2017, 29(5): 538-540.
17
崔冰, 胡秋根, 王岩. 肝吸虫性胆管炎的磁共振胰胆管成像诊断[J]. 中华放射学杂志, 2003, 37(8): 742-746.
18
任玉君, 袁代清. 多层螺旋CT诊断胆道梗阻性疾病68例分析[J]. 实用医院临床杂志, 2012, 9(6): 82-84.
19
Laothong U, Pinlaor P, Hiraku Y, et al. Protective effect of melatonin against Opisthorchis viverrini-induced oxidative and nitrosative DNA damage and liver injury in hamsters [J]. J Pineal Res, 2010, 49(3): 271-282.
20
Serradell MC, Guasconi L, Masih DT. Involvement of a mitochondrial pathway and key role of hydrogen peroxide during eosinophil apoptosis induced by excretory-secretory products from Fasciola hepatica [J]. Mol Biochem Parasitol, 2009, 163(2): 95-106.
21
Kim EM, Kwak YS, Yi MH, et al. Clonorchis sinensis antigens alter hepatic macrophage polarization in vitro and in vivo [J]. PLoS Negl Trop Dis, 2017, 11(5): e0005614.
22
Surapaitoon A, Suttiprapa S, Mairiang E, et al. Subsets of inflammatory cytokine gene polymorphisms are associated with risk of carcinogenic liver fluke opisthorchis viverrini-associated advanced periductal fibrosis and cholangiocarcinoma [J]. Korean J Parasitol, 2017, 55(3): 295-304.
23
Pak JH, Bashir Q, Kim IK, et al. Clonorchis sinensis excretory-secretory products promote the migration and invasion of cholangiocarcinoma cells by activating the integrin β4-FAK/Src signaling pathway [J]. Mol Biochem Parasitol, 2017, 214: 1-9.
24
Plieskatt JL, Deenonpoe R, Mulvenna JP, et al. Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome [J]. FASEB J, 2013, 27(11): 4572-4584.
25
Sripa B, Kaewkes S, Intapan PM, et al. Food-borne trematodiases in Southeast Asia epidemiology, pathology, clinical manifestation and control [J]. Adv Parasitol, 2010,72: 305-350.
26
Rim HJ. Clonorchiasis: an update [J]. J Helminthol, 2005, 79(3): 269-281.
27
Chaiyadet S, Smout M, Johnson M, et al. Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production [J]. Int J Parasitol, 2015, 45(12): 773-781.
28
van der Windt DJ, Sud V, Zhang H, et al. Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in non-alcoholic steatohepatitis [J]. Hepatology, 2018, doi: 10.1002/hep.29914.
29
Lim JH, Mairiang E, Ahn GH. Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis [J]. Abdom Imaging, 2008, 33(2): 157-165.
30
Woo H, Han JK, Kim JH, et al. In-vivo monitoring of development of cholangiocarcinoma induced with C. sinensis and N-nitrosodimethylamine in Syrian golen hamsters using ultrasonography and magnetic resonance imaging: a preliminary study [J]. Eur Radiol, 2017, 27(4): 1740-1747.
31
Choi BI, Han JK, Hong ST, et al. Clonorchiasis and cholangiocarcinoma: etiologic relationship and imaging diagnosis [J]. Clin Microbiol Rev, 2004, 17(3): 540-552.
32
Singh S, Muir AJ, Dieterich DT, et al. American Gastroenterological Association Institute technical review on the Role of elastography in chronic liver diseases [J]. Gastroenterology, 2017, 152(6): 1544-1577.
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