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中华医学超声杂志(电子版) ›› 2022, Vol. 19 ›› Issue (07) : 675 -678. doi: 10.3877/cma.j.issn.1672-6448.2022.07.014

妇产科超声影像学

顶颌径/顶臀径比值在早孕期胎儿染色体三倍体筛查中的应用价值
李颖思1, 杨昕1, 潘敏1, 韩瑾1, 张丽娜1, 吴思琪1, 甄理1, 李东至1, 廖灿1,()   
  1. 1. 510000 广州医科大学广州妇女儿童医疗中心产前诊断中心
  • 收稿日期:2020-09-22 出版日期:2022-07-01
  • 通信作者: 廖灿

Parietal mandible length/crown-lump length ratio in first-trimester screening for triploidy

Yingsi Li1, Xin Yang1, Min Pan1   

  • Received:2020-09-22 Published:2022-07-01
引用本文:

李颖思, 杨昕, 潘敏, 韩瑾, 张丽娜, 吴思琪, 甄理, 李东至, 廖灿. 顶颌径/顶臀径比值在早孕期胎儿染色体三倍体筛查中的应用价值[J]. 中华医学超声杂志(电子版), 2022, 19(07): 675-678.

Yingsi Li, Xin Yang, Min Pan. Parietal mandible length/crown-lump length ratio in first-trimester screening for triploidy[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2022, 19(07): 675-678.

图1 超声检查正中矢状面测量胎儿顶颌长。图a为正常胎儿;图b为三倍体胎儿
图2 测量者1与测量者2的顶颌径长度(PML)/顶臀径长度(CRL)比值的测量重复性分析。图a为测量者1的测量者内误差分析,图b为测量者2的测量者内误差分析,图c为2名测量者间的测量误差分析
图3 11~13+6周正常胎儿顶颌径长度(PML)正常值曲线:PML(mm)=3.65+0.38×顶臀径长度(CRL)(R2=0.821,P<0.001)
图4 11~13+6周正常胎儿顶颌径长度/顶臀径长度(PML/CRL)值正常值曲线:PML/CRL=0.5-9.21×CRL(R2=0.093,P<0.001)
表1 早孕期不同顶臀径胎儿PML/CRL比值分布趋势
图5 11~13+6周正常胎儿与三倍体胎儿顶颌径长度(PML)曲线图
图6 11~13+6周正常胎儿与三倍体综合征胎儿顶颌径长度(PML)/顶臀径长度(CRL)曲线图
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