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中华医学超声杂志(电子版) ›› 2025, Vol. 22 ›› Issue (06) : 583 -585. doi: 10.3877/cma.j.issn.1672-6448.2025.06.014

病例报告

早期子宫中肾样腺癌影像学表现一例
陈程1, 俞梅2, 王馨梅3, 王铭1, 刘真真1, 戴晴1, 苏娜1,()   
  1. 1100730 中国医学科学院 北京协和医学院 北京协和医院超声医学科
    2100730 中国医学科学院 北京协和医学院 北京协和医院妇产科
    3100730 中国医学科学院 北京协和医学院 北京协和医院病理科
  • 收稿日期:2025-04-07 出版日期:2025-06-01
  • 通信作者: 苏娜
  • 基金资助:
    国家自然科学基金(82402293)

Imaging manifestations of early-stage mesonephric-like adenocarcinoma of the uterus: a case report and literature review

Cheng Chen, Mei Yu, Xinmei Wang   

  • Received:2025-04-07 Published:2025-06-01
引用本文:

陈程, 俞梅, 王馨梅, 王铭, 刘真真, 戴晴, 苏娜. 早期子宫中肾样腺癌影像学表现一例[J/OL]. 中华医学超声杂志(电子版), 2025, 22(06): 583-585.

Cheng Chen, Mei Yu, Xinmei Wang. Imaging manifestations of early-stage mesonephric-like adenocarcinoma of the uterus: a case report and literature review[J/OL]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2025, 22(06): 583-585.

图1 子宫中肾样腺癌超声声像图。图a,b分别为子宫纵切面和横切面超声灰阶声像图:子宫中央区域见低回声病变(黄色三角形),其中心可见线状的宫腔高回声线(橘黄色箭头),内膜欠清,病变外缘欠规整,周边环绕的等回声子宫肌层厚薄不均;图c,d为彩色多普勒成像提示低回声区域内较丰富条状血流信号,呈向心性较对称分布,与放射状动脉走行相似,局部稍紊乱
图2 子宫中肾样腺癌盆腔常规及增强MRI图像。图a,b分别为常规、增强MRI提示子宫中部(宫腔及肌层)团块状肿物累及深肌层(白色箭头)
图3 子宫中肾样腺癌手术标本大体及病理图片。图a为开腹子宫内膜癌分期术,剖视子宫见黄白色肿瘤组织占据宫腔,侵及深肌层;图b为术后病理图片(HE ×5),可见病灶侵及肌壁浅层
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Zhang HY, Liu Y, Fu YT, et al. A rare case of mesonephric-like adenocarcinoma in the uterus [J]. Asian J Surg, 2024, 47(6): 2737-2738.
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Kanao S, Urano M, Fujita K, et al. Mesonephric-like adenocarcinoma of the uterine corpus with focal sarcomatous differentiation: A case report [J]. Fujita Med J, 2025, 11(1): 54-58.
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McFarland M, Quick CM, McCluggage WG. Hormone receptor-negative, thyroid transcription factor 1-positive uterine and ovarian adenocarcinomas: report of a series of mesonephric-like adenocarcinomas [J]. Histopathology, 2016, 68(7): 1013-1020.
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WHO Classification of Tumours Editorial Board. WHO classification of tumours: female genital tumours [M]. 5th ed. Lyon: IARC Publications, 2020: 77-78.
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Ma T, Chai M, Shou H, et al. Mesonephric-like adenocarcinoma of uterine corpus: a clinicopathological and targeted genomic profiling study in a single institution [J]. Front Oncol, 2022, 12: 911695.
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Horn LC, Höhn AK, Krücken I, et al. Mesonephric-like adenocarcinomas of the uterine corpus: report of a case series and review of the literature indicating poor prognosis for this subtype of endometrial adenocarcinoma [J]. J Cancer Res Clin Oncol, 2020, 146(4): 971-983.
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McCluggage WG. Mesonephric-like adenocarcinoma of the female genital tract: from morphologic observations to a well-characterized carcinoma with aggressive clinical behavior [J]. Adv Anat Pathol, 2022, 29(4): 208-216.
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Kim H, Na K, Bae GE, et al. Mesonephric-like adenocarcinoma of the uterine corpus: comprehensive immunohistochemical analyses using markers for mesonephric, endometrioid and serous tumors [J]. Diagnostics (Basel), 2021, 11(11): 2042.
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Pors J, Segura S, Chiu DS, et al. Clinicopathologic characteristics of mesonephric adenocarcinomas and mesonephric-like adenocarcinomas in the gynecologic tract: A multi-institutional Study [J]. Am J Surg Pathol, 2021,45(4): 498-506.
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