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中华医学超声杂志(电子版) ›› 2026, Vol. 23 ›› Issue (06) : 512 -516. doi: 10.3877/cma.j.issn.1672-6448.2026.06.011

综述

胎儿心脏定量分析技术在胎儿心脏评估中的应用进展
董姗姗, 殷林亮†(), 潘琦, 张俊, 陆冰   
  1. 215002 苏州,南京医科大学附属苏州医院 苏州市立医院超声医学中心
  • 收稿日期:2026-02-14 出版日期:2026-06-01
  • 通信作者: 殷林亮

Fetal heart quantification: evolving applications in fetal cardiac assessment

Shanshan Dong, Linliang Yin†(), Qi Pan   

  • Received:2026-02-14 Published:2026-06-01
  • Corresponding author: Linliang Yin
引用本文:

董姗姗, 殷林亮, 潘琦, 张俊, 陆冰. 胎儿心脏定量分析技术在胎儿心脏评估中的应用进展[J/OL]. 中华医学超声杂志(电子版), 2026, 23(06): 512-516.

Shanshan Dong, Linliang Yin, Qi Pan. Fetal heart quantification: evolving applications in fetal cardiac assessment[J/OL]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2026, 23(06): 512-516.

图1 胎儿心脏定量技术显示胎儿心功能模式图。图a为M型超声结合二维动态图像确定舒张末期及收缩末期的时间节点;图b为自动追踪左、右心室心内膜边界形成动态轨迹图;图c为左心室和右心室的24节段球形指数曲线图
图2 胎儿四腔心切面计算心脏整体球形指数。 注:4CV L ED为四腔心舒张末期心脏长径,4CV TW ED为四腔心舒张末期心脏横径
表1 Fetal HQ在胎儿心脏评估中的临床应用总览
表2 胎儿心脏定量分析技术主要技术参数的临床意义及可重复性总结
1
van der Linde D, Konings EE, Slager MA, et al. Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis[J]. J Am Coll Cardiol, 2011, 58(21): 2241-2247.
2
Luo Y, Xiao F, Long C, et al. Evaluation of the sphericity index of the fetal heart during middle and late pregnancy using fetalHQ[J]. J Matern Fetal Neonatal Med, 2022, 35(25): 8006-8011.
3
DeVore GR, Klas B, Satou G, et al. 24-segment sphericity index: a new technique to evaluate fetal cardiac diastolic shape[J]. Ultrasound Obstet Gynecol, 2018, 51(5): 650-658.
4
伍颖恒, 马小燕. 产前超声检测中孕期胎儿心脏发育[J]. 中国医学影像技术, 2011, 27(11): 2294-2298.
5
狄秋怡, 龙湘党, 宁靖, 等. 胎儿心脏定量技术评估正常胎儿心脏形态与功能: 一项前瞻性队列研究[J]. 中华围产医学杂志, 2025, 28(3): 211-218.
6
Hu W, Wang M, Bian J, et al. Evaluation of fetal cardiac morphology and function by fetal heart quantification technique in the normal second and third trimesters[J]. Transl Pediatr, 2024, 13(7): 1106-1118.
7
DeVore GR, Klas B, Satou G, et al. Quantitative evaluation of fetal right and left ventricular fractional area change using speckle-tracking technology[J]. Ultrasound Obstet Gynecol, 2019, 53(2): 219-228.
8
Kapusta L, Mainzer G, Weiner Z, et al. Changes in fetal left and right ventricular strain mechanics during normal pregnancy[J]. J Am Soc Echocardiogr, 2013, 26(10): 1193-1200.
9
Huang C, Li J, Qin G, et al. Maternal hypertensive disorder of pregnancy and offspring early-onset cardiovascular disease in childhood, adolescence, and young adulthood: A national population-based cohort study[J]. PLoS Med, 2021, 18(9): e1003805.
10
Catalano PM, McIntyre HD, Cruickshank JK, et al. The hyperglycemia and adverse pregnancy outcome study: associations of GDM and obesity with pregnancy outcomes[J]. Diabetes Care, 2012, 35(4): 780-786.
11
Li S, Wang L, Yang H, et al. Changes in the shape and function of the fetal heart of pre-and gestational diabetes mothers[J]. BMC Pregnancy Childbirth, 2024, 24(1): 57.
12
Zhang P, Fu X, Zhao L, et al. Quantifying fetal heart health in gestational diabetes: a new approach with fetal heart quantification technology[J]. Front Pharmacol, 2024, 15: 1394885.
13
Yovera L, Zaharia M, Jachymski T, et al. Impact of gestational diabetes mellitus on fetal cardiac morphology and function: cohort comparison of second-and third-trimester fetuses[J]. Ultrasound Obstet Gynecol, 2021, 57(4): 607-613.
14
Miranda JO, Cerqueira RJ, Ramalho C, et al. Fetal cardiac function in maternal diabetes: a conventional and speckle-tracking echocardiographic study[J]. J Am Soc Echocardiogr, 2018, 31(3): 333-341.
15
Gireadă R, Socolov D, Mihălceanu E, et al. Evaluation of fetal cardiac geometry and contractility in gestational diabetes mellitus by two-dimensional speckle-tracking technology[J]. Diagnostics (Basel), 2022, 12(9): 2053.
16
Tan F, Yang J, Shen Y, et al. Evaluating fetal heart morphology in hypertensive disorders of pregnancy using the fetal heart quantitative technique[J]. Transl Pediatr, 2022, 11(11): 1804-1812.
17
Zhang Y, Zhang L, Sun C, et al. The effects of hypertensive disorders of pregnancy on fetal myocardial remodelling and cardiac function assessed by two-dimensional speckle tracking imaging[J]. J Matern Fetal Neonatal Med, 2025, 38(1): 2531146.
18
Peng Y, Feng W, Yu CX, et al. Fetal heart quantification ultrasound technology for the quantitative analysis of fetal cardiac morphology and function in hypertensive disorders of pregnancy[J]. Quant Imaging Med Surg, 2025, 15(4): 3517-3531.
19
Wang L, Fu X, Ren X, et al. Evaluation of fetal cardiac morphology and function in hypertensive disorders of pregnancy using Fetal HQ technology combined with uterine artery ultrasound parameters[J]. Front Cardiovasc Med, 2025, 12: 1558034.
20
詹梦娜, 赵博文, 彭晓慧, 等. 胎儿心脏定量分析技术评价左心室流出道梗阻胎儿心脏功能和形态[J]. 中华超声影像学杂志, 2021, 30(10): 854-860.
21
Yang J, Tan F, Shen Y, et al. Assessing coarctation of the aorta with fetal heart quantification technology[J]. Matern Fetal Med, 2024, 6(3): 147-155.
22
Pan C, Li J, Huang L, et al. Assessing fetal heart morphology and function in fetuses with right ventricular outflow obstruction by fetal heart quantitative technique[J]. J Ultrasound Med, 2025, 44(8): 1391-1404.
23
张小敏,赵博文,潘美,等. 胎儿心脏定量分析技术对肺动脉狭窄及肺动脉闭锁胎儿心脏形态及功能的初步研究[J]. 中华超声影像学杂志, 2024, 33(6): 489-496.
24
Hobbins JC, Gumina DL, Zaretsky MV, et al. Size and shape of the four-chamber view of the fetal heart in fetuses with an estimated fetal weight less than the tenth centile[J]. Am J Obstet Gynecol, 2019, 221(5): 495.e1-495.e9.
25
Xiao L, Chen D, Wang L, et al. Assessment of fetal cardiac morphology and function in fetal growth restriction: insights from fetal heart quantification technology[J]. Quant Imaging Med Surg, 2025, 15(8): 6713-6724.
26
Rodríguez-López M, Cruz-Lemini M, Valenzuela-Alcaraz B, et al. Descriptive analysis of different phenotypes of cardiac remodeling in fetal growth restriction[J]. Ultrasound Obstet Gynecol, 2017, 50(2): 207-214.
27
Wang W, Liu J, Yin H, et al. Evaluation of fetal cardiac function in fetal growth restriction via fetal HQ analysis based on two-dimensional STI[J]. J Obstet Gynaecol Res, 2023, 49(6): 1514-1524.
28
Chen Y, Lv X, Yang L, et al. Evaluation of fetal heart size, morphology and function with fetal growth restriction using fetal HQ[J]. BMC Pregnancy Childbirth, 2024, 24(1): 751.
29
Domínguez-Gallardo C, Ginjaume-García N, Ullmo J, et al. Longitudinal behavior of left-ventricular strain in fetal growth restriction[J]. Diagnostics (Basel), 2023, 13(7): 1252.
30
Mlodawski J, Zmelonek-Znamirowska A, Pawlik L, et al. Reproducibility challenges in fetal cardiac function analysis with 2D speckle-tracking echocardiography: insights from FetalHQ[J]. J Clin Med, 2025, 14(10): 3301.
31
Nogué L, Gómez O, Izquierdo N, et al. Feasibility of 4D-spatio temporal image correlation (STIC) in the comprehensive assessment of the fetal heart using FetalHQ®[J]. J Clin Med, 2022, 11(5): 1414.
32
Sacco A, Kazi A, Nzelu D, et al. Feasibility and reproducibility of speckle tracking echocardiography in routine assessment of the fetal heart in a low-risk population[J]. J Perinat Med, 2025, 53(4): 509-516.
33
Di Tonto A, Nogue L, Valentini B, et al. Reproducibility analysis of two speckle tracking software for the antenatal semiautomated assessment of the fetal cardiac function[J]. Fetal Diagn Ther, 2025, 52(1): 8-18.
34
Huntley ES, Hernandez-Andrade E, Soto E, et al. Novel speckle tracking analysis showed excellent reproducibility for size and shape of the fetal heart and good reproducibility for strain and fractional shortening[J]. Fetal Diagn Ther, 2021, 48(7): 541-550.
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