To evaluate the clinical value of ultrasound in screening and selected termination of multiple pregnancy.

46 cases of multiple pregnancy who received ultrasound screening and selected termination in our prenatal diagnosis center from July 2011 to April 2015 were collected. The type of multiple pregnancy, chorionicity, fetal abnormalities and indications of selected termination were analyzed, and the pregnancy process and clinical results after the selected termination were followed up.

Of all the cases,28 cases were twin pregnancy which were all dichorionic/diamniotic. 5 cases of the twin pregnancy underwent selected termination due to mothers` demand, in which all fetuses were normal. 21 cases of the twin pregnancy were terminated, because structural abnormalities were detected in one of the twins by ultrasound. The rest two cases of twin pregnancy were terminated because of pregnant complication.15 cases were triplet pregnancy. Of them, 8 cases of these were trichorionic/triamniotic and all fetuses were normal. But due to mothers` demand, selected termination was performed in each case. 5 cases of the triplet pregnancy were dichorionic/triamniotic. And the monochorionic/diamniotic twins were selected terminated in 3 cases. Also structural abnormalities were detected in one of the monochorionic/diamniotic twins in 2 cases. Of these two cases, monochorionic/diamniotic twins selected termination was performed in both twins in one case and in the abnormal twin in another case. Among 15 triplet pregnancy cases, 2 cases were dichorionic/diamniotic pregnancy with one abnormal fetus, and the two fetuses were all selected terminated. 4 cases were quadruplet pregnancy, all fetuses were normal but two fetuses were reduced in each case. According to the follow-up results, 28 fetuses were retained after selected termination, of which one fetus with left multicystic renal dysplasia was detected in the second trimester, two fetuses were abortion, and the remaining twenty five fetuses were normal. Fetuses were all normal after selected termination in triplet and quadruplet pregnancy.

Ultrasonic examination of early pregnancy can confirm the type of multiple pregnancy and detect the abnormal fetus. Prenatal diagnosis in early period and appropriate intervention can improve the pregnancy outcome of multiple pregnancy.