To achieve efficient, rational, safe and standardized ultrasound contrast infusion, relevant medical, and nursing experts in China summarized the domestic and international literature and clinical experience evidence. After a thorough discussion under the principles of evidence-based medicine, the consensus was proposed, aiming to provide reference opinions for achieving standardization of safe ultrasound contrast infusion in China. The consensus introduces the current situation and safety of ultrasound contrast agent application, relevant regulations and procedures, standardized care before, during, and after imaging, and proposes 16 recommendations. It suggests that the current ultrasound contrast agents approved for market use in China have a high safety profile, and it recommends that healthcare professionals should dispense and administer them according to the latest instructions or expert consensus and that they should be standardized in terms of contrast room management, risk planning, and personnel qualifications.