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Chinese Journal of Medical Ultrasound (Electronic Edition) >

2021 , Vol. 18 >Issue 05: 487 - 494

DOI: https://doi.org/10.3877/cma.j.issn.1672-6448.2021.05.009

Abdominal Ultrasound

Contrast-enhanced ultrasound for evaluation of efficacy of transcatheter hepatic artery embolization in patients with hepatocellular carcinoma

  • Peng Han ,
  • Xiang Fei ,
  • Bo Jiang ,
  • Chong He ,
  • Yukun Luo ,
  • Zhijun Wang
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  • 1. Department of Ultrasound, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
    2. Department of Interventional Radiology, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China

Received date: 2019-10-28

  Online published: 2021-06-10

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Abstract

Objective

To investigate the feasibility of evaluating the effect of embolization by transhepatic arterial contrast-enhanced ultrasonography immediately after transarterial chemoembolization (TACE) to predict the short-term curative effect for hepatocellular carcinoma (HCC).

Methods

A total of 50 HCC lesions in 39 patients treated by TACE underwent transhepatic artery contrast-enhanced ultrasonography before and immediately after operation at the First Medical Center of Chinese PLA General Hospital from September 2018 to March 2019. According to the maximum area ratio of internal enhancement of the tumor after surgery and before surgery and the maximum covering ratio of drainage area before and after surgery, Spearman correlation analysis was used to compare MRI results within 1 to 3 months after TACE between groups.

Results

The effect of embolization evaluated by immediate postoperative tumor enhancement ratio and postoperative covering ratio of drainage area was related to the short-term curative effect judged by modified response evalution criteria in solid tumors (mRECIST), and the postoperative covering ratio of drainage area had a more significant correlation (r=0.516, P＜0.001 and r=0.716, P＜0.001, respectively).

Conclusion

The evaluation of embolization effect immediately after TACE by transhepatic artery contrast-enhanced ultrasonography has a high correlation with the short-term curative effect evaluated by mRECIST, which can provide a good imaging reference value for predicting the short-term curative effect after tumor operation.

Key words： Transhepatic artery contrast-enhanced ultrasonography; Hepatocellular carcinoma; Transarterial chemoembolization

Cite this article

Peng Han , Xiang Fei , Bo Jiang , Chong He , Yukun Luo , Zhijun Wang . Contrast-enhanced ultrasound for evaluation of efficacy of transcatheter hepatic artery embolization in patients with hepatocellular carcinoma[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2021 , 18(05) : 487 -494 . DOI: 10.3877/cma.j.issn.1672-6448.2021.05.009

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