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中华医学超声杂志(电子版) ›› 2022, Vol. 19 ›› Issue (06) : 597 -599. doi: 10.3877/cma.j.issn.1672-6448.2022.06.020

病例报告

筛状桑葚亚型甲状腺乳头状癌一例并文献复习
杨景茹1, 禹静1, 张月娟1, 李建省1, 宁春平1, 李秀梅1, 牛晓燕1,()   
  1. 1. 266003 青岛大学附属医院超声科
  • 收稿日期:2020-08-17 出版日期:2022-06-01
  • 通信作者: 牛晓燕

Cribriform-morular variant of papillary thyroid carcinoma: a case report and literature review

Jingru Yang1, Jing Yu1, Yuejuan Zhang1   

  • Received:2020-08-17 Published:2022-06-01
引用本文:

杨景茹, 禹静, 张月娟, 李建省, 宁春平, 李秀梅, 牛晓燕. 筛状桑葚亚型甲状腺乳头状癌一例并文献复习[J]. 中华医学超声杂志(电子版), 2022, 19(06): 597-599.

Jingru Yang, Jing Yu, Yuejuan Zhang. Cribriform-morular variant of papillary thyroid carcinoma: a case report and literature review[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2022, 19(06): 597-599.

图1 CT及超声显示腹腔占位。图a为CT示左下腹巨大软组织密度团块,与周围肠管分界不清;图b为超声示左下腹巨大实性不均质回声团块注:Mass为团块;RK为右肾;LR为左肾
图2 肠镜及胃镜检查提示胃息肉、结肠息肉,行内镜下息肉电切术。图a为结肠镜下见全大肠弥漫性分布大小不等的息肉;图b为胃镜下见胃底弥漫性分布大小不等的息肉;图c为内镜下息肉热活检钳电切术后图像
图3 甲状腺结节(筛状桑葚亚型甲状腺乳头状癌)超声图像。图a,b分别为结节的超声纵切面和横切面图像,超声示甲状腺结节纵横比<1,边界清晰,边缘规则,内部呈略低回声,见多发小囊变区,无钙化灶;图c为彩色多普勒示结节内部血流信号较丰富
图4 筛状桑葚亚型甲状腺乳头状癌穿刺活检及甲状腺切除术后病理图像。图a为细针穿刺细胞学病理图像示平铺团片状的肿瘤细胞(HE ×100);图b为组织病理学图像示肿瘤细胞呈实性及筛状排列(HE ×100);图c为免疫组化示β-catenin异常阳性表达于细胞核(EnVison ×100);图d为免疫组化示甲状腺转录因子1(TTF-1)阳性表达于肿瘤细胞核(EnVison ×100);图e为免疫组化示肿瘤细胞不表达甲状腺球蛋白(TG阴性)(EnVison ×100);图f为免疫组化示雌激素受体(PR)阳性表达于肿瘤细胞核(EnVison ×100)
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