切换至 "中华医学电子期刊资源库"
高级检索
中华医学超声杂志（电子版）

中华医学超声杂志（电子版） ›› 2023, Vol. 20 ›› Issue (12) : 1312 -1316. doi: 10.3877/cma.j.issn.1672-6448.2023.12.017

综述

斑点追踪超声心动图在肥厚型心肌病不良心血管事件风险评估中的应用进展
夏靖涵1, 尹立雪2, 李明星1, 李文华3,†()   
  1. 1. 646000　泸州，西南医科大学附属医院超声医学科
    2. 610072　成都，四川省医学科学院·四川省人民医院（电子科技大学附属医院）心血管超声及心功能科　超声心脏电生理学与生物力学四川省重点实验室　四川省心血管病临床医学研究中心（国家心血管疾病临床医学研究中心四川分中心）
    3. 646000　泸州，西南医科大学附属医院超声医学科;610072　成都，四川省医学科学院·四川省人民医院（电子科技大学附属医院）心血管超声及心功能科　超声心脏电生理学与生物力学四川省重点实验室　四川省心血管病临床医学研究中心（国家心血管疾病临床医学研究中心四川分中心）
  • 收稿日期:2023-03-17 出版日期:2023-12-01
  • 通信作者: 李文华
  • 基金资助:
    四川省科技厅-四川省自然科学基金(2023NSFSC0641)

Progress in application of speck-tracking echocardiography in risk assessment of adverse cardiovascular events in hypertrophic cardiomyopathy

Jinghan Xia, Lixue Yin, Mingxing Li   

  • Received:2023-03-17 Published:2023-12-01
全文 ( ) 下载PDF ( ) 导出引用
引用本文：

夏靖涵, 尹立雪, 李明星, 李文华. 斑点追踪超声心动图在肥厚型心肌病不良心血管事件风险评估中的应用进展[J]. 中华医学超声杂志（电子版）, 2023, 20(12): 1312-1316.

Jinghan Xia, Lixue Yin, Mingxing Li. Progress in application of speck-tracking echocardiography in risk assessment of adverse cardiovascular events in hypertrophic cardiomyopathy[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2023, 20(12): 1312-1316.

肥厚型心肌病（hypertrophic cardiomyopathy，HCM）是临床最常见的遗传性心肌病，其发病率为1/500~1/200。绝大多数呈常染色体显性遗传，研究证实40%~60%的HCM是由编码心肌肌小节收缩蛋白的基因突变所致。成人HCM诊断标准如下：排除其他心脏、系统性或代谢性疾病导致左心室肥厚的情况，二维超声心动图或心血管磁共振成像显示左心室任意节段的舒张末期最大室壁厚度≥15 mm，有家族史或基因检测阳性时≥13 mm。针对儿童HCM，左心室厚度超过同龄、同性别和同体表面积儿童平均值两个标准差（Z值>2）用于具有明确家族史或基因型阳性儿童的早期诊断；Z值>2.5适用于无家族史且无症状儿童HCM的早期识别。

图1 左心室局部和整体纵向应变分析。图a、b、c分别为心尖两腔、三腔、四腔切面的节段纵向应变值；图d为18节段纵向应变峰值牛眼图和整体纵向应变峰值
图2 左心室局部和整体圆周应变分析。图a、b、c分别为二尖瓣、乳头肌、心尖水平短轴切面的节段圆周应变值；图d为18节段圆周应变峰值牛眼图和整体圆周应变峰值
图3 右心室纵向应变分析。图a为心尖四腔切面下心内膜斑点追踪；图b为纵向应变曲线及应变值
图4 左心房纵向应变分析。图a为心尖四腔切面下心内膜斑点追踪；图b是以左心室舒张末期为零应变点的应变曲线和测值；图c为以左心房收缩期起始为零应变点的应变曲线和测值
1
Maron BJ, Desai MY, Nishimura RA, et al. Diagnosis and evaluation of hypertrophic cardiomyopathy: JACC state-of-the-art review [J]. J Am Coll Cardiol, 2022, 79(4): 372-389.
2
Geske JB, Ommen SR, Gersh BJ. Hypertrophic cardiomyopathy: clinical update [J]. JACC Heart Fail, 2018, 6(5): 364-375.
3
Ommen SR, Mital S, Burke MA, et al. 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines [J]. Circulation, 2020, 142(25): e533-e557.
4
唐璐, 周年伟, 蒋英英, 等. 肥厚型心肌病的基因型与表型分析[J]. 中华超声影像学杂志, 2020, 29(3): 219-223.
5
Lee HJ, Kim J, Chang SA, et al. Major clinical issues in hypertrophic cardiomyopathy [J]. Korean Circ J, 2022, 52(8): 563-575.
6
贾梅, 李晴, 叶晶晶, 等.三维斑点追踪显像对成人肥厚型心肌病患者左室心肌应变、扭转运动与其形态及整体收缩功能的关联性研究[J].中华超声影像学杂志, 2021, 30(5): 369-375.
7
Muraru D, Niero A, Rodriguez-Zanella H, et al. Three-dimensional speckle-tracking echocardiography: benefits and limitations of integrating myocardial mechanics with three-dimensional imaging [J]. Cardiovasc Diagn Ther, 2018, 8(1): 101-117.
8
赵洁, 王静, 刘丽文, 等.三维斑点追踪技术对于携带MYH7基因突变的肥厚型心肌病患者预后评估的价值[J].中华心血管病杂志, 2020, 48(4): 287-293.
9
Badano LP, Kolias TJ, Muraru D, et al. Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging [J]. Eur Heart J Cardiovasc Imaging, 2018, 19(6): 591-600.
10
邢长洋, 袁丽君, 张宇新, 等. 欧洲心血管影像协会/美国超声心动图学会《二维斑点追踪超声心动图应用于左心房及右心应变成像的规范化共识》解读[J/OL].中华医学超声杂志(电子版), 2021, 18(12): 1135-1139.
11
Voigt JU, Cvijic M. 2- and 3-dimensional myocardial strain in cardiac health and disease [J]. JACC Cardiovasc Imaging, 2019, 12(9): 1849-1863.
12
Cameli M, Mandoli GE, Sciaccaluga C, et al. More than 10 years of speckle tracking echocardiography: Still a novel technique or a definite tool for clinical practice? [J]. Echocardiography, 2019, 36(5): 958-970.
13
Teixeira R. Three-dimensional speckle tracking echocardiography: The future is now [J]. Rev Port Cardiol (Engl Ed), 2018, 37(4): 339-340.
14
Moore B, Semsarian C, Chan KH, et al. Sudden cardiac death and ventricular arrhythmias in hypertrophic cardiomyopathy [J]. Heart Lung Circ, 2019, 28(1): 146-154.
15
Task Force M, Elliott PM, Anastasakis A, et al. 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC) [J]. Eur Heart J, 2014, 35(39): 2733-2779.
16
Verge MP, Cochet H, Reynaud A, et al. Characterization of hypertrophic cardiomyopathy according to global, regional, and multi-layer longitudinal strain analysis, and prediction of sudden cardiac death [J]. Int J Cardiovasc Imaging, 2018, 34(7): 1091-1098.
17
Candan O, Gecmen C, Kahyaoglu M, et al. Left atrial dysfunction as marker of arrhythmic events in patients with hypertrophic cardiomyopathy [J]. Anatol J Cardiol, 2022, 26(10): 771-777.
18
Candan O, Gecmen C, Kalayci A, et al. Left ventricular twist in hypertrophic cardiomyopathy : Predictor of nonsustained ventricular tachycardia [J]. Herz, 2019, 44(3): 238-246.
19
Haland TF, Almaas VM, Hasselberg NE, et al. Strain echocardiography is related to fibrosis and ventricular arrhythmias in hypertrophic cardiomyopathy [J]. Eur Heart J Cardiovasc Imaging, 2016, 17(6): 613-621.
20
Hopman L, Mulder MJ, Van Der Laan AM, et al. Left atrial strain is associated with arrhythmia recurrence after atrial fibrillation ablation: Cardiac magnetic resonance rapid strain vs. feature tracking strain [J]. Int J Cardiol, 2023, 378: 23-31.
21
Candan O, Gecmen C, Kahyaoglu M, et al. Clinical utility of left atrial asynchrony and mechanical function in patients with hypertrophic cardiomyopathy [J]. Acta Cardiol Sin, 2022, 38(2): 141-150.
22
Pezel T, Venkatesh BA, De Vasconcellos HD, et al. Left atrioventricular coupling index as a prognostic marker of cardiovascular events: the MESA study [J]. Hypertension, 2021, 78(3): 661-671.
23
Wabich E, Zienciuk-Krajka A, Nowak R, et al. Comprehensive echocardiography of left atrium and left ventricle using modern techniques helps in better revealing atrial fibrillation in patients with hypertrophic cardiomyopathy [J]. Diagnostics (Basel), 2021, 11(7): 1288.
24
Kawakami H, Ramkumar S, Nolan M, et al. Left atrial mechanical dispersion assessed by strain echocardiography as an independent predictor of new-onset atrial fibrillation: a case-control study [J]. J Am Soc Echocardiogr, 2019, 32(10): 1268-1276.e1263.
25
Park JJ, Park JB, Park JH, et al. Global longitudinal strain to predict mortality in patients with acute heart failure [J]. J Am Coll Cardiol, 2018, 71(18): 1947-1957.
26
Hiemstra YL, Debonnaire P, Van Zwet EW, et al. Development of and progression of overt heart failure in nonobstructive hypertrophic cardiomyopathy [J]. Am J Cardiol, 2018, 122(4): 656-662.
27
Hiemstra YL, Debonnaire P, Bootsma M, et al. Prevalence and prognostic implications of right ventricular dysfunction in patients with hypertrophic cardiomyopathy [J]. Am J Cardiol, 2019, 124(4): 604-612.
28
Rowin EJ, Maron BJ, Wells S, et al. Usefulness of global longitudinal strain to predict heart failure progression in patients with nonobstructive hypertrophic cardiomyopathy [J]. Am J Cardiol, 2021, 151: 86-92.
29
Jain V, Ghosh R, Gupta M, et al. Contemporary narrative review on left atrial strain mechanics in echocardiography: cardiomyopathy, valvular heart disease and beyond [J]. Cardiovasc Diagn Ther, 2021, 11(3): 924-938.
30
Rosca M, Popescu BA, Beladan CC, et al. Left atrial dysfunction as a correlate of heart failure symptoms in hypertrophic cardiomyopathy [J]. J Am Soc Echocardiogr, 2010, 23(10): 1090-1098.
31
Lee HJ, Kim HK, Rhee TM, et al. Left atrial reservoir strain-based left ventricular diastolic function grading and incident heart failure in hypertrophic cardiomyopathy [J]. Circ Cardiovasc Imaging, 2022, 15(4): e013556.
32
Rakesh K, Rajesh GN, Vellani H. 3D speckle tracking echocardioimagedata strain pattern in hypertrophic cardiomyopathy and its relation with sudden cardiac death risk markers [J]. Indian Heart J, 2021, 73(4): 451-457.
33
黎梦, 章子铭, 吕清, 等.三维斑点追踪技术评价肥厚型心肌病患者左心室心肌力学特点[J/OL].中华医学超声杂志(电子版), 2021, 18(3): 250-257.
34
付海蓉, 胡冬梅, 孟海生, 等.三维斑点追踪技术评价左室射血分数正常的肥厚型心肌病患者左心室心肌收缩特性研究[J].中国社区医师, 2020, 36(4): 137-138.
35
周金玲, 王凤, 白晖, 等.三维斑点追踪成像评价肥厚型心肌病患者左室扭转功能[J].临床超声医学杂志, 2019, 21(10): 739-742.
36
纳丽莎, 贾梅, 朱睿, 等.三维斑点追踪超声心动图定量评价成人肥厚型心肌病早期左室心肌收缩力学变化[J].宁夏医学杂志, 2019, 41(12): 1060-1063.
37
李慕子, 李慧, 孟红, 等.实时三维超声心动图自动定量技术评价肥厚型心肌病患者左心房容积及功能的应用价值[J].中国循环杂志, 2022, 37(5): 487-493.
38
Liu Q, Chen L, Liu X, et al. Evaluation of left ventricular myocardial work in patients with hyperthyroidism with different heart rates with noninvasive pressure-strain loop based on two-dimensional speck tracking imaging [J]. Quant Imaging Med Surg, 2023, 13(4): 2248-2261.
39
Hiemstra YL, Van Der Bijl P, El Mahdiui M, et al. Myocardial work in nonobstructive hypertrophic cardiomyopathy: implications for outcome [J]. J Am Soc Echocardiogr, 2020, 33(10): 1201-1208.
40
张苗, 袁建军, 王一洒, 等. 压力-应变环在评价肥厚型心肌病左室心肌做功中的应用[J]. 中华超声影像学杂志, 2020, 29(7): 576-580.
41
Galli E, Vitel E, Schnell F, et al. Myocardial constructive work is impaired in hypertrophic cardiomyopathy and predicts left ventricular fibrosis [J]. Echocardiography, 2019, 36(1): 74-82.
No related articles found!
阅读次数
全文


摘要

版权所有 中华医学会 中华医学电子音像出版社有限责任公司  京ICP备14006079号-1  网络出版服务许可证：(署)网出证(京)字第075号