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中华医学超声杂志(电子版) ›› 2025, Vol. 22 ›› Issue (11) : 1093 -1096. doi: 10.3877/cma.j.issn.1672-6448.2025.11.014

病例报告

丑角鱼鳞病产前超声表现二例
张涛, 陈欣林(), 黄慧   
  1. 430070 武汉,湖北省妇幼保健院超声诊断科
  • 收稿日期:2025-06-26 出版日期:2025-11-01
  • 通信作者: 陈欣林

Prenatal ultrasonographic findings in two cases of harlequin ichthyosis

Tao Zhang, Xinlin Chen()   

  • Received:2025-06-26 Published:2025-11-01
  • Corresponding author: Xinlin Chen
引用本文:

张涛, 陈欣林, 黄慧. 丑角鱼鳞病产前超声表现二例[J/OL]. 中华医学超声杂志(电子版), 2025, 22(11): 1093-1096.

Tao Zhang, Xinlin Chen. Prenatal ultrasonographic findings in two cases of harlequin ichthyosis[J/OL]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2025, 22(11): 1093-1096.

图1 先天性丑角鱼鳞病(病例1)超声图像。图a示胎儿头皮明显增厚;图b示胎儿双眼球前方均见一向前突起的团状稍高回声;图c示胎儿嘴唇增厚外翻;图d示胎儿胸腹部及背部皮肤增厚回声增强,多处回声连续性中断;图e示胎儿双手呈握拳状;图f示双足皮肤增厚
图2 先天性丑角鱼鳞病(病例1)引产后大体标本图像。图a示引产后大体标本头皮明显增厚,多处皲裂;双眼睑外翻,双眼外上方均见一红色肉样结构,张口,嘴唇增厚外翻;图b示大体标本全身皮肤铠甲样增厚,多处皲裂;图c示大体标本双手握拳状,指关节水肿;图d示小腿皮肤大片皲裂,双足挛缩
图3 先天性丑角鱼鳞病(病例2)超声及MRI图像。图a为超声图像示孕18+6周胎儿嘴唇稍增厚;图b为超声图像示孕24周胎儿嘴唇增厚外翻;图c为超声图像示孕24周胎儿头皮增厚;图d为超声图像示孕24周胎儿足底皮肤增厚;图e为三维超声显示胎儿嘴唇增厚外翻;图f为MRI显示胎儿头皮及足底皮肤增厚
图4 先天性丑角鱼鳞病(病例2)引产后大体标本图像。图a示引产后大体标本见头、面、耳皮肤呈淡黄色,嘴呈鱼嘴状,无鼻梁;图b示大体标本腹股沟区皮肤见较浅条状皲裂;图c显示双足屈曲;图d显示双手屈曲
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