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心血管超声影像学

缩窄性心包炎超声心动图漏诊分析

  • 谭焜月 1 ,
  • 郭静 1 ,
  • 赵正凯 2 ,
  • 蔡秋艺 2 ,
  • 王淑珍 1 ,
  • 高小强 1 ,
  • 熊峰 , 1,
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  • 1.610031 成都市第三人民医院心内科 成都市心血管病研究所
  • 2.610031 成都市第三人民医院放射影像科
熊峰,Email:xiong.
Xiong Feng, Email:xiong.

Copy editor: 汪荣

网络出版日期: 2025-04-01

基金资助

四川省自然科学基金面上项目(2024NSFSC0646)成都市第三人民医院院内科研项目(CSYYN-01-2023-066)

版权

版权归中华医学会所有。 未经授权,不得转载、摘编本刊文章,不得使用本刊的版式设计。 除非特别声明,本刊刊出的所有文章不代表中华医学会和本刊编委会的观点。

Causes of missed diagnosis of constrictive pericarditis by echocardiography

  • Kunyue Tan 1 ,
  • Jing Guo 1 ,
  • Zhengkai Zhao 2 ,
  • Qiuyi Cai 2 ,
  • Shuzhen Wang 1 ,
  • Xiaoqiang Gao 1 ,
  • Feng Xiong , 1,
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  • 1.Department of Cardiology,The Third People's Hospital of Chengdu,Chengdu 610031,China
  • 2.Department of Radiology,The Third People's Hospital of Chengdu,Chengdu 610031,China

Online published: 2025-04-01

Copyright

Copyright by Chinese Medical Association No content published by the journals of Chinese Medical Association may be reproduced or abridged without authorization. Please do not use or copy the layout and design of the journals without permission. All articles published represent the opinions of the authors, and do not reflect the official policy of the Chinese Medical Association or the Editorial Board, unless this is clearly specified.

摘要

目的

分析超声心动图漏诊的缩窄性心包炎患者的临床及影像学特征。

方法

回顾性纳入2020 年1 月至2024 年12 月于成都市第三人民医院就诊的缩窄性心包炎患者共92 例。所有患者均最终经手术及术后病理证实,诊断明确。所有患者均行超声心动图及CT 检查,其中82 例首次超声心动图检查确诊缩窄性心包炎(超声诊断组),10 例首次检查漏诊(超声漏诊组)。对比分析2 组的临床及影像学特征。

结果

与超声诊断组比较,漏诊组患者病程较短[9.00(11.00)个月 vs 2.50(7.90)个月,P<0.05]。超声诊断组中有更高比例的患者合并肝静脉扩张(31.7%,26/82)、腹腔积液(54.9%,45/82)及胸腔积液(73.2%,60/82),2 组比较差异有统计学意义(P均<0.05)。与超声诊断组比较,漏诊组心脏形态改变较不明显。超声诊断组与漏诊组的左心房前后径[41.00(8.30)mm vs 37.50(4.30)mm,P<0.05]、左心室舒张末期内径[40.50(4.00)mm vs 45.50(4.30)mm,P<0.05]、右心房横径[41.00(7.00)mm vs 36.50(9.00)mm,P<0.05]、右房室角[(80.71±30.55)°vs(106.50±35.87)°,P<0.05]、心尖球形指数[69.00(29.00) vs 84.00(25.00),P<0.05]及左心室质量指数 [(69.79±15.91)g/m2vs(84.51±13.53)g/m2P<0.05]比较,差异均有统计学意义。2 组患者心包均增厚,但漏诊组不合并心包钙化。超声诊断组与漏诊组行心包剥脱术后围术期死亡率[(3.7%,3/82)vs (0,0/10),P>0.05]及不良事件发生率差异无统计学意义。

结论

缩窄性心包炎的超声心动图表现具有一定特征性,但临床实践中存在漏诊。漏诊病例多为病程早期患者,这部分患者虽有心包增厚,但无心包钙化,同时心脏形态改变不明显,临床症状相对较轻。结合患者病史特征进行多模态影像学评估比单一依赖超声心动图更有利于做出正确诊断。

本文引用格式

谭焜月 , 郭静 , 赵正凯 , 蔡秋艺 , 王淑珍 , 高小强 , 熊峰 . 缩窄性心包炎超声心动图漏诊分析[J]. 中华医学超声杂志(电子版), 2025 , 22(02) : 139 -145 . DOI: 10.3877/cma.j.issn.1672-6448.2025.02.007

Abstract

Objective

To analyze the causes of missed diagnosis of constrictive pericarditis by echocardiography, and investigate the safety of pericardiectomy in patients with atypical constrictive pericarditis.

Methods

A total of 92 patients with constrictive pericarditis who visited the Third People's Hospital of Chengdu from January 2020 to December 2024 were retrospectively included.All patients underwent echocardiography and CT examination.Based on the first echocardiographic examination, the patients were divided into an accurate diagnosis group(n=82)and a missed diagnosis group(n=10),and the clinical and imaging characteristics of the two groups were compared and analyzed.

Results

Compared to the accurate diagnosis group, the missed diagnosis group had a shorter disease course [9.00(11.00)months vs 2.50(7.90)months, P<0.05] and milder liver function impairment.The accurate diagnosis group exhibited higher proportions of hepatic vein dilation, ascites, and pleural effusion (all P<0.05).The missed diagnosis group demonstrated milder cardiac morphological changes, including the changes of left atrial size [41.00(8.30)mm vs 37.50(4.30)mm, P<0.05], left ventricular size [40.50(4.00)mm vs 45.50(4.30)mm, P<0.05], right atrial size [41.00(7.00)mm vs 36.50(9.00)mm,P<0.05], right atrioventricular angle [(80.71±30.55)° vs(106.50±35.87)°, P<0.05], apical sphericity index [69.00(29.00) vs 84.00(25.00), P<0.05], and left ventricular mass index [(69.79±15.91)g/m2 vs(84.51±13.53)g/m2P<0.05].Both groups had thickened pericardium, but the missed diagnosis group did not have calcifled pericardium.Postoperative mortality [3.7% (3/82) vs 0 (0/10)] and adverse event rates showed no signiflcant difference between the two groups (P>0.05).

Conclusion

Echocardiography exhibits characteristic flndings for constrictive pericarditis, but misdiagnosis occurs in clinical practice.Missed cases are often early-stage patients with pericardial thickening but no calciflcation, subtle cardiac morphological changes, and milder symptoms.Multimodal imaging evaluation combined with clinical history can improve diagnostic accuracy compared with reliance on echocardiography alone.

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