Value of Q-analysis real-time elasticity in differentiating between benign and malignant thyroid nodules

doi:10.3877/cma.j.issn.1672-6448.2015.05.014

Abstract

Abstract:

Objective

To investigate the value of Q-analysis real-time elasticity in differentiating between benign and malignant thyroid nodules.

Methods

Eighty-six thyroid nodules in 62 patients with pathologic diagnosis were included in this study and were examined using Q-analysis real-time elasticity. The real-time elasticity features were observed and the quantitative index including the whole elasticity rate and the local elasticity rate were compared between benign and malignant nodules.

Results

There were 51 benign and 35 malignant nodules according to histopathological examination. The Q-analysis curve of real-time elasticity of benign nodules was smoother and with lower peak, compared with that of malignant nodules. The whole elasticity rate of malignant nodules were significantly higher than that of benign nodules (3.59±0.84 vs 2.32±0.56, P=0.000). And the local elasticity rate of malignant nodules were significantly higher than that of benign nodules (3.96±1.32 vs 2.39±0.58, P=0.000). The cutoff point of whole elasticity rate for the differential diagnosis was 3.25 with sensitivity, specificity and diagnostic accuracy as 71.4%, 96.1% and 86.0% respectively. The cutoff point of local elasticity rate for the differential diagnosis was 3.45 with sensitivity, specificity and diagnostic accuracy as 68.6%, 96.1% and 84.9% respectively. The diagnostic efficiency of whole elasticity rate and local elasticity rate had no significant difference (P=0.591).

Conclusions

Q-analysis real-time elasticity could provide the real-time elasticity features of thyroid nodules. The whole and local elasticity rate as the quantitative index contributed to the differential diagnosis of benign and malignant thyroid nodules.

Key words: Thyroid nodules, Elasticity imaging techniques, Ultrasonography.

Yingying Yang, Kairong Lei, Xuchu Wu, Jingjing Long, Fangli Ye, Yating Yang, Keqin Cui, Chengfu Song. Value of Q-analysis real-time elasticity in differentiating between benign and malignant thyroid nodules[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2015, 12(07): 564-567.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2015.05.014

https://chaosheng.cma-cmc.com.cn/EN/Y2015/V12/I07/564

Figures/Tables 3

References 11

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组别	个数	整体弹性比值	局部弹性比值
恶性结节	35	3.59±0.84	3.96±1.32
良性结节	51	2.32±0.56	2.39±0.58
t值	?	8.307	6.837
P值	?	0.000	0.000

组别	个数	整体弹性比值	局部弹性比值
恶性结节	35	3.59±0.84	3.96±1.32
良性结节	51	2.32±0.56	2.39±0.58
t值	?	8.307	6.837
P值	?	0.000	0.000

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