Evaluating fetal bladder development with three-dimensional ultrasound virtual organ computer-aided analysis

doi:10.3877/cma.j.issn.1672-6448.2016.05.006

Abstract

Abstract:

Objective

To evaluate the development of fetuses bladder by ultrasound virtual organ computer-aided analysis (VOCAL) technique, and establish the maximum and minimum bladder volume reference ranges of normal fetuses to conclude the relationship between the volume and gestational age.

Methods

From April, 2014 to November, a total of 345 normal fetuses at the 16-38^th gestational week (15 normal fetuses at each gestational week) underwent examinination in Shengjing Hospital of China Medical University and were selected. Maximum and minimum bladder volumes of fetuses were measured and the relationship between bladder volume and gestational age were analyzed.

Results

The maximum and minimum bladder volume were obtained in 345 fetuses at the 16-38^th gestational week, including average value, standard deviation and 95% confidence intervals. The maximum and minimum bladder volume of normal fetuses were curvilinearly associated with gestational age (R²_max=0.99, R²_min=0.98, all P<0.01).

Conclusion

Three dimensional ultrasound VOCAL technique can measure the bladder volume which is increasing with the gestational age.

Key words: Fetus, Urinary bladder, Ultrasonography, Prenatal

Xian Li, Bing Wang, Ailu Cai. Evaluating fetal bladder development with three-dimensional ultrasound virtual organ computer-aided analysis[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2016, 13(05): 349-352.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2016.05.006

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References 17

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孕周（周）	例数	最大值		最小值
孕周（周）	例数	±s	95%CI	±s	95%CI
16	15	0.77±0.14	0.09，2.51	0.42±0.09	0.37，0.65
17	15	1.15±0.25	0.45，2.83	0.51±0.09	0.37，0.63
18	15	2.66±0.26	1.13，3.14	0.51±0.08	0.38，0.63
19	15	3.76±0.33	1.95，4.20	0.60±0.06	0.40，0.65
20	15	4.57±0.29	2.92，5.17	0.63±0.06	0.43，0.68
21	15	5.55±0.27	4.03，6.25	0.66±0.06	0.48，0.72
22	15	6.54±0.26	5.27，7.52	0.69±0.04	0.53，0.77
23	15	7.52±0.29	6.62，8.87	0.71±0.04	0.59，0.83
24	15	8.53±0.29	8.07，10.31	0.73±0.04	0.66，0.90
25	15	9.79±0.64	9.59，11.82	0.75±0.07	0.74，0.98
26	15	10.82±0.36	11.17，13.39	0.83±0.05	0.83，1.07
27	15	13.84±0.19	12.79，15.01	1.07±0.07	0.92，1.16
28	15	14.71±0.36	14.43，16.65	1.12±0.05	1.02，1.26
29	15	16.68±0.36	16.07，18.03	1.23±0.05	1.13，1.37
30	15	19.91±0.86	17.71，19.95	1.39±0.05	1.24，1.48
31	15	20.40±0.34	19.31，21.57	1.48±0.05	1.35，1.59
32	15	22.57±0.39	20.88，23.14	1.64±0.04	1.46，1.71
33	15	23.52±0.12	22.39，24.65	1.72±0.04	1.58，1.82
34	15	24.84±0.47	23.83，26.07	1.87±0.03	1.70，1.94
35	15	26.03±0.26	25.16，27.41	1.93±0.02	1.82，2.06
36	15	27.52±0.26	26.37，28.66	2.07±0.03	1.94，2.18
37	15	28.67±0.31	27.42，29.80	2.15±0.03	2.05，2.30
38	15	29.38±0.18	28.26，30.85	2.27±0.04	2.15，2.43

孕周（周）	例数	最大值		最小值
孕周（周）	例数	±s	95%CI	±s	95%CI
16	15	0.77±0.14	0.09，2.51	0.42±0.09	0.37，0.65
17	15	1.15±0.25	0.45，2.83	0.51±0.09	0.37，0.63
18	15	2.66±0.26	1.13，3.14	0.51±0.08	0.38，0.63
19	15	3.76±0.33	1.95，4.20	0.60±0.06	0.40，0.65
20	15	4.57±0.29	2.92，5.17	0.63±0.06	0.43，0.68
21	15	5.55±0.27	4.03，6.25	0.66±0.06	0.48，0.72
22	15	6.54±0.26	5.27，7.52	0.69±0.04	0.53，0.77
23	15	7.52±0.29	6.62，8.87	0.71±0.04	0.59，0.83
24	15	8.53±0.29	8.07，10.31	0.73±0.04	0.66，0.90
25	15	9.79±0.64	9.59，11.82	0.75±0.07	0.74，0.98
26	15	10.82±0.36	11.17，13.39	0.83±0.05	0.83，1.07
27	15	13.84±0.19	12.79，15.01	1.07±0.07	0.92，1.16
28	15	14.71±0.36	14.43，16.65	1.12±0.05	1.02，1.26
29	15	16.68±0.36	16.07，18.03	1.23±0.05	1.13，1.37
30	15	19.91±0.86	17.71，19.95	1.39±0.05	1.24，1.48
31	15	20.40±0.34	19.31，21.57	1.48±0.05	1.35，1.59
32	15	22.57±0.39	20.88，23.14	1.64±0.04	1.46，1.71
33	15	23.52±0.12	22.39，24.65	1.72±0.04	1.58，1.82
34	15	24.84±0.47	23.83，26.07	1.87±0.03	1.70，1.94
35	15	26.03±0.26	25.16，27.41	1.93±0.02	1.82，2.06
36	15	27.52±0.26	26.37，28.66	2.07±0.03	1.94，2.18
37	15	28.67±0.31	27.42，29.80	2.15±0.03	2.05，2.30
38	15	29.38±0.18	28.26，30.85	2.27±0.04	2.15，2.43

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