Quantitative evaluation of carotid plaque vulnerability by using GSM based on three dimensional ultrasound

doi:10.3877/cma.j.issn.1672-6448.2017.01.008

Abstract

Abstract:

Objective

To quantitatively evaluate the vulnerability of carotid plaques in patients with acute ischemic cerebral infarction by using Gray-scale median (GSM) based on Three-dimensional ultrasound (3D-US).

Methods

Totally 207 patients were examined with carotid plaques in the PLA Army General Hospital from December 2015 to August 2016, including 102 patients with acute cerebralischemic stroke (cerebral infarction group) and 105 patients without cerebral infarction (control group). The Vascular plaque quantification (VPQ) software was applied to acquire GSM value of carotid plaques automatically.

Results

The GSM value of carotid plaques in cerebral infarction group was significantly lower than that in control group (44.78±11.58 vs 54.36±11.99, t=7.70, P<0.01), and the low density lipoprotein in the cerebral infarction group was significantly higher than that in the control group [(3.51±1.20) mmol/L vs (3.10±1.07) mmol/L, t=1.58, P<0.05]. There was no significant difference between the two groups in age, gender, body mass index, smoking, drinking, history of diabetes, history of hypertension, systolic blood pressure, diastolic blood pressure, triglyceride, total cholesterol, high density lipoprotein, plaque thickness, plaque area stenosis rate and plaque volume (all P>0.05).

Conclusion

The GSM value of carotid plaques based on 3D-US-VPQ technology can effectively reflect the vulnerability of carotid plaques, and may be valuable in the risk assessment of carotid plaques.

Key words: Carotid artery diseases, Echocardiography, three-dimensional, Brain infarction

Xiuling Wang, Minyu Zhang, Guichun Ding, Hongbin Wang, Jianhua Wang. Quantitative evaluation of carotid plaque vulnerability by using GSM based on three dimensional ultrasound[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2017, 14(01): 23-28.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2017.01.008

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References 20

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组别	例数	年龄（岁，±s）	男性（例，%）	BMI（kg/m²，±s）	吸烟（例，%）	饮酒（例，%）	糖尿病（例，%）	高血压病（例，%）
脑梗死组	102	68.4±10.3	58（56.9）	25.59±3.00	33（32.4）	15（14.3）	39（38.2）	68（66.7）
对照组	105	65.4±10.6	63（60.0）	25.99±4.65	37（35.2）	21（20.6）	28（26.7）	61（58.1）
统计值	?	t=1.47	χ²=0.21	t=1.31	χ²=0.19	χ²=1.43	χ²=3.16	χ²=1.62
P值	?	>0.05	>0.05	>0.05	>0.05	>0.05	>0.05	>0.05
组别	例数	收缩压（mmHg，±s）	舒张压（mmHg，±s）	TG（mmol/L，±s）	TC（mmol/L，±s）	LDL（mmol/L，±s）	HDL（mmol/L，±s）
脑梗死组	102	146.27±12.94	89.03±12.41	1.77±0.55	4.75±0.96	3.51±1.20	1.08±0.54
对照组	105	143.75±13.28	86.21±11.54	1.71±0.48	5.07±1.08	3.10±1.07	1.26±0.45
统计值	?	t=1.39	t=1.41	t=0.59	t=1.89	t=1.58	t=1.86
P值	?	>0.05	>0.05	>0.05	>0.05	<0.05	>0.05

组别	例数	年龄（岁，±s）	男性（例，%）	BMI（kg/m²，±s）	吸烟（例，%）	饮酒（例，%）	糖尿病（例，%）	高血压病（例，%）
脑梗死组	102	68.4±10.3	58（56.9）	25.59±3.00	33（32.4）	15（14.3）	39（38.2）	68（66.7）
对照组	105	65.4±10.6	63（60.0）	25.99±4.65	37（35.2）	21（20.6）	28（26.7）	61（58.1）
统计值	?	t=1.47	χ²=0.21	t=1.31	χ²=0.19	χ²=1.43	χ²=3.16	χ²=1.62
P值	?	>0.05	>0.05	>0.05	>0.05	>0.05	>0.05	>0.05
组别	例数	收缩压（mmHg，±s）	舒张压（mmHg，±s）	TG（mmol/L，±s）	TC（mmol/L，±s）	LDL（mmol/L，±s）	HDL（mmol/L，±s）
脑梗死组	102	146.27±12.94	89.03±12.41	1.77±0.55	4.75±0.96	3.51±1.20	1.08±0.54
对照组	105	143.75±13.28	86.21±11.54	1.71±0.48	5.07±1.08	3.10±1.07	1.26±0.45
统计值	?	t=1.39	t=1.41	t=0.59	t=1.89	t=1.58	t=1.86
P值	?	>0.05	>0.05	>0.05	>0.05	<0.05	>0.05

组别	斑块数	GSM	斑块厚度（mm）	面积狭窄率（%）	斑块体积（mm³）
脑梗死组	180	44.78±11.58	3.49±1.00	52.4±9.3	190.40±60.69
对照组	179	54.36±11.99	3.30±0.85	49.7±9.3	179.38±63.54
t值	?	7.70	1.16	1.44	1.59
P值	?	<0.01	>0.05	>0.05	>0.05

组别	斑块数	GSM	斑块厚度（mm）	面积狭窄率（%）	斑块体积（mm³）
脑梗死组	180	44.78±11.58	3.49±1.00	52.4±9.3	190.40±60.69
对照组	179	54.36±11.99	3.30±0.85	49.7±9.3	179.38±63.54
t值	?	7.70	1.16	1.44	1.59
P值	?	<0.01	>0.05	>0.05	>0.05

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