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Chinese Journal of Medical Ultrasound (Electronic Edition) ›› 2017, Vol. 14 ›› Issue (10): 794-798. doi: 10.3877/cma.j.issn.1672-6448.2017.10.015

Special Issue:

• Obstetric and Gynecologic Ultrasound • Previous Articles     Next Articles

Value of ultrasound-guided fine needle aspiration cytology in the assessment of ovarian neoplasms and retroperitoneal metastatic lymph nodes

Junping Liu1,(), Weimin Mao2, Dong Xu3, Haimiao Xu4, Ye Cheng4, Hanmei Lou2, Liyu Chen5, Min Lyu5, Fang Cheng5   

  1. 1. Department of Interventional Ultrasound, Zhejiang Cancer Hospital, Hangzhou 310022, China; Zhejiang Key Laboratory of the Diagnosis & Treatment Technology on Thoracic Oncology, Hangzhou 310022, China
    2. Zhejiang Key Laboratory of the Diagnosis & Treatment Technology on Thoracic Oncology, Hangzhou 310022, China
    3. Department of Interventional Ultrasound, Zhejiang Cancer Hospital, Hangzhou 310022, China; Department of Gynecologic Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, China
    4. Department of Pathology, Zhejiang Cancer Hospital, Hangzhou 310022, China
    5. Department of Gynecologic Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, China
  • Received:2016-12-18 Online:2017-10-01 Published:2017-10-01
  • Contact: Junping Liu
  • About author:
    Corresponding author: Liu Junping, Email:

Abstract:

Objective

To evaluate the diagnostic value of ultrasound-guided fine needle aspiration cytology(US-FNAC)in the assessment of radiologically detected ovarian neoplasms and retroperitoneal metastatic lymph nodes.

Methods

FNAC was performed under ultrasound guidance on 126 patients suspected of ovarian neoplasms and retroperitoneal metastatic lymph nodes. Cytologic examination was performed after staining smears with the haematoxylin and eosin method. Clinical data were retrieved from the medical records and all cytological specimens were reviewed. In these cases, the cytologic findings were correlated with histology of the primary tumor and were compared with surgical pathology.

Results

Satisfactory sampling was obtained in 86.2% of punctures, and cytological diagnosis was made in 85.7% cases. The size of the lymph nodes punctured was less than 20 mm in 93.5% cases, with the sensitivity of 81.6%、86.2%, specificity of 95.8%、100.0%, positive predictive value of 98.3%、100.0%, negative predictive value of 63.9%、33.3%, and accuracy of 85.3%、87.1%. Seven patients presented slight abdominal discomfort, and relieved without clinical treatment.

Conclusions

The fine needle aspiration technique has excellent positive predictive value and low morbidity. US-FNAC, as the valuable investigation, is not only useful in the diagnosis of ovarian masses and lymph nodes but can also help in choosing appropriate management. From our experience, US-FNAC can be added in follow-up of selected patients in whom the cytological identification of such masses and nodes is significant for the patient′s treatment.

Key words: Retroperitoneal lymph nodes, Ovarian oncology, Ultrasound, Fine needle aspiration cytology, Clinical value

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