To observe wall motion, left ventricle volume, and complications in coronary heart disease (CHD) patients by left ventricular opacification (LVO) and assess the value of LVO examination in the diagnosis and treatment of CHD.

The differences of TTE and LVO were compared by the results of ESV, EDV, and LVEF, which were measured through biplane Simpson's method in 65 patients with CHD at Peking University People's Hospital from May 2016 to December 2018, using paired-samples t test and Chi-square test. We also observed the left ventricular structure and wall motion and analyzed the relationship between wall motion score index (WMSI) and LVEF through linear regression.

Left ventricular EDV and ESV measured by TTE were (90.77±35.17) ml and (49.20±29.56) ml, respectively; the corresponding values measured by LVO were (126.86±41.74) ml and (68.89±36.25) ml. There were significant differences in the values measured by TTE and LVO (t=-14.589, -8.780; P＜0.001). LVEF measured by TTE and LVO was classified into different groups, respectively (LVEF≥50%; LVEF=40%-49%; LVEF＜40%), and there was a significant difference in the composition of groups between them (χ²=28.685, P＜0.001). TTE suggested 11 cases of suspected left ventricular mural thrombosis, of which eight were confirmed by LVO, and another five cases were diagnosed by LVO. Twenty cases of left ventricular aneurysm were diagnosed by LVO, of which 11 were confirmed and 9 were missed by TTE. There was a significant difference between LVO and TTE in the diagnosis of CHD complications, apical thrombosis, and ventricular aneurysm (χ²=19.211, 22.234; P＜0.001). WMSI calculated by LVO and TTE was (1.68±0.43) and (1.50±0.24), respectively, and they both had a negative correlation with LVEF results [(48.50±13.49)% and (48.94±13.27)%; r=-0.630, -0.625; P＜0.01).

LVO allows to observe ventricular wall segment clearly, assessing left ventricular systolic function more accurately, and diagnose apical thrombosis and ventricular aneurysm more sensitively by visualizing left ventricular endocardial boundary in CHD patients.