To assess the value of ultrasound-guided percutaneous lung biopsy in the diagnosis of peripheral lung lesions(PPL).

A total of 176 PPL patients with complete clinical data were selected at the Second Affiliated Hospital of Xi'an Jiaotong University from January 2015 to December 2019. All patients were clearly diagnosed as having PPL by chest CT and other imaging examinations, and underwent ultrasound-guided percutaneous lung biopsy and surgical treatment to obtain final pathological results. The success rate of ultrasound-guided puncture was calculated. Using the final postoperative pathological results as the gold standard, the performance of ultrasound-guided percutaneous lung biopsy in the diagnosis of PPL was assessed.The incidence of complications after puncture was also recorded.

Of the 176 patients included, biopsies were successfully in obtained in 172 cases, with a success rate of 97.72% (172/176). Compared with the final postoperative pathological results, 168 cases were diagnosed correctly by ultrasound-guided needle biopsy, with a diagnostic accuracy rate of 97.67% (168/172). The remaining four cases of lung adenocarcinoma with necrotic infection were diagnosed as inflammatory necrotic tissue by needle biopsy. Taking the postoperative pathological results as the gold standard, the sensitivity, specificity, negative predictive value, and positive predictive value of ultrasound-guided percutaneous lung puncture in diagnosing peripheral lung malignant tumors were 96.77% (120/124), 100% (48/48), 92.31 % (48/52), and 100% (120/120), respectively. After ultrasound-guided percutaneous lung biopsy,9 cases developed a small amount of pneumothorax, 8 developed a small amount of pleural effusion, and 6 had blood shot sputum. The complication rate was 13.07% (23/176).

Ultrasound-guided percutaneous lung biopsy is a minimally invasive, convenient, and safe examination technique. It has high diagnostic efficiency for PPL and has important clinical application value in the pathological diagnosis and treatment of PPL.