Comparative study of enhanced ultrasound and contrast-enhanced helical CT in diagnosis of renal masses

doi:10.3877/cma.j.issn.1672-6448.2022.11.014

Abstract

Abstract:

Objective

To evaluate the value of contrast-enhanced helical computed tomography (CECT) and enhanced ultrasound (CEUS) in differentiating benign and malignant renal masses.

Methods

We retrospectively analyzed 48 patients with renal masses diagnosed by pathology at the First Affiliated Hospital of Harbin Medical University from September 2020 to March 2021, all of whom underwent CEUS and CECT examinations, and CEUS with Sonazoid. These patients were divided into either a benign group (n=10) or a malignant group (n=38) according to the pathological results. The diagnostic efficacy of the two imaging methods and the difference in the detection rates of malignant enhancement signs between them were compared by χ² test. The mean enhancement duration of Sonazoid-CEUS in normal renal parenchyma was statistically calculated.

Results

Hyper-enhancement, inhomogeneous enhancement, fast fill in, and fast wash out showed higher diagnostic value in renal malignant tumors. The positive rate of "hyper-enhancement" in CEUS was obviously higher than that in CECT (92.11% vs 73.68%, χ²=4.547, P=0.33). CEUS had high application value in the diagnosis of benign and malignant renal tumors. The accuracy and specificity of CEUS were higher than those of CECT (95.83% vs 93.75%; 90.00% vs 80.00%), and its sensitivity was the same as that of CECT (97.37% vs 97.37%), the differences were not statistically significant (P＞0.05). The mean duration of Sonazoid-CEUS enhancement in normal renal parenchyma was (6.43±1.20) min, with 34 patients (70.83%, 34/48) exceeding 7 min.

Conclusion

CEUS with Sonazoid prolongs the enhancement time of renal tumors and renal parenchyma. It has similar diagnostic efficacy to CECT in the assessment of benign and malignant renal tumors.

Key words: Renal masses, Sonazoid, Contrast-enhanced ultrasound, Diagnosis

Xiangru Dong, Yinzhu Chu, Fuxin Li, Feng Zhang, Yuying Zhang, Changjun Wu. Comparative study of enhanced ultrasound and contrast-enhanced helical CT in diagnosis of renal masses[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2022, 19(11): 1238-1243.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2022.11.014

https://chaosheng.cma-cmc.com.cn/EN/Y2022/V19/I11/1238

Figures/Tables 5

References 13

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检查方法	准确性	敏感度	特异度	阳性预测值	阴性预测值
CEUS	95.83（46/48）	97.37（37/38）	90.00（9/10）	97.37（37/38）	90.00（9/10）
CECT	93.75（45/48）	97.37（37/38）	80.00（8/10）	94.87（37/39）	88.89（8/9）
χ²值	0.211	0.000	0.392	0.320	0.006
P值	0.500	0.753	0.500	0.510	0.737

检查方法	准确性	敏感度	特异度	阳性预测值	阴性预测值
CEUS	95.83（46/48）	97.37（37/38）	90.00（9/10）	97.37（37/38）	90.00（9/10）
CECT	93.75（45/48）	97.37（37/38）	80.00（8/10）	94.87（37/39）	88.89（8/9）
χ²值	0.211	0.000	0.392	0.320	0.006
P值	0.500	0.753	0.500	0.510	0.737

检查方法	例数	高增强	不均匀增强	快进	快出
CEUS	38	35（92.11）	26（68.42）	33（86.84）	24（63.15）
CECT	38	28（73.68）	29（76.32）	30（78.95）	30（78.95）
χ²值		4.547	0.592	0.835	2.303
P值		0.033	0.442	0.361	0.129

检查方法	例数	高增强	不均匀增强	快进	快出
CEUS	38	35（92.11）	26（68.42）	33（86.84）	24（63.15）
CECT	38	28（73.68）	29（76.32）	30（78.95）	30（78.95）
χ²值		4.547	0.592	0.835	2.303
P值		0.033	0.442	0.361	0.129

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