Feasibility of contrast-enhanced ultrasonography in evaluation of renal perfusion in spinal cord injured patients with hydronephrosis

doi:10.3877/cma.j.issn.1672-6448.2019.02.007

Abstract

Abstract:

Objective

To evaluate the feasibility of contrast-enhanced ultrasonography in assessing renal perfusion in patients with spinal cord injury complicated with hydronephrosis.

Methods

Sixteen patients with spinal cord injury complicated with hydronephrosis (study group) and nine patients with normal kidneys (control group) were routinely examined by ultrasound. Contrast-enhanced ultrasonography was performed and compared with the results of renography. The renal perfusion was observed, and the images were collected. Then, the region of interest (ROI) was selected in the renal cortex, and the time-intensity curve was plotted. The four parameters of the time-intensity curve, time to initial peak (TTP), peak intensity (DPI), slope of ascending curve, and area under the curve (AUC), were compared between the two groups by the independent-samples rank sum test. P<0.05 were considered statistically significant.

Results

In the study group, the TTP [right kidney: 11.94 (9.90-18.87); left kidney: 22.61 (11.84-28.20)] was significantly delayed, and the DPI [right kidney: 10.08 (9.34-11.04); left kidney: 9.17 (8.86-11.88)], slope of ascending curve [right kidney: 0.92 (0.66-1.13); left kidney: 0.47 (0.35-1.03)], and the AUC [right kidney: 836.01 (676.03-1050.95); left kidney: 906.56 (722.11-1043.17)] were significantly decreased when compared with the control group (Z=-3.114, -2.860, -3.001, -2.661, -3.608, -3.011, and -2.415, respectively; P<0.05 for all).

Conclusion

Contrast-enhanced ultrasonography can be used to evaluate renal perfusion in patients with spinal cord injury complicated with hydronephrosis.

Key words: Hydronephrosis, Contrast-enhanced ultrasonography, Renal perfusion, Spinal cord injury

Yushuang Liu, Wen He, Linggang Cheng, Xuemei Li, Hongxia Zhang. Feasibility of contrast-enhanced ultrasonography in evaluation of renal perfusion in spinal cord injured patients with hydronephrosis[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2019, 16(02): 115-119.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2019.02.007

https://chaosheng.cma-cmc.com.cn/EN/Y2019/V16/I02/115

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References 18

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组别		例数	RTTP（s）	RDPI（dB）	RA（dB/s）	RAUC（dBs）	LTTP（s）	LDPI（dB）	LA（dB/s）	LAUC（dBs）
SCI组		16	11.94（9.90~18.87）	10.08（9.34~11.04）	0.92（0.66~1.13）	836.01（676.03~1050.95）	22.61（11.84~28.20）	9.17（8.86~11.88）	0.47（0.35~1.03）	906.56（722.11~1043.17）
健康对照组		9	7.25（6.73~10.00）	11.98（10.85~12.98）	1.65（1.09~1.77）	1085.97（1008.18~1258.99）	7.85（6.74~8.67）	11.02（9.51~12.66）	1.40（1.23~1.54）	1065.55（1006.73~1265.16）
?	Z值	?	-3.114	-2.860	-3.001	-2.661	-3.608	-1.163	-3.011	-2.415
?	P值	?	0.002	0.004	0.003	0.008	0.000	0.245	0.003	0.016

组别		例数	RTTP（s）	RDPI（dB）	RA（dB/s）	RAUC（dBs）	LTTP（s）	LDPI（dB）	LA（dB/s）	LAUC（dBs）
SCI组		16	11.94（9.90~18.87）	10.08（9.34~11.04）	0.92（0.66~1.13）	836.01（676.03~1050.95）	22.61（11.84~28.20）	9.17（8.86~11.88）	0.47（0.35~1.03）	906.56（722.11~1043.17）
健康对照组		9	7.25（6.73~10.00）	11.98（10.85~12.98）	1.65（1.09~1.77）	1085.97（1008.18~1258.99）	7.85（6.74~8.67）	11.02（9.51~12.66）	1.40（1.23~1.54）	1065.55（1006.73~1265.16）
?	Z值	?	-3.114	-2.860	-3.001	-2.661	-3.608	-1.163	-3.011	-2.415
?	P值	?	0.002	0.004	0.003	0.008	0.000	0.245	0.003	0.016

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