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中华医学超声杂志(电子版) ›› 2017, Vol. 14 ›› Issue (10) : 730 -733. doi: 10.3877/cma.j.issn.1672-6448.2017.10.003

所属专题: 文献

浅表器官超声影像学

常规超声与彩色多普勒及超声造影在视网膜下出血诊断中的应用价值
沈琳1, 杨文利1,(), 李栋军1, 王子杨1, 陈伟1, 赵琦1, 李逸丰1, 崔蕊1   
  1. 1. 100730 北京,首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科学与视觉科学重点实验室
  • 收稿日期:2017-07-12 出版日期:2017-10-01
  • 通信作者: 杨文利

Diagnostic value of conventional ultrasound, color Doppler ultrasonography and contrast-enhanced ultrasound in sub-retinal hemorrhage

Lin Shen1, Wenli Yang1,(), Dongjun Li1, Ziyang Wang1, Wei Chen1, Qi Zhao1, Yifeng Li1, Rui Cui1   

  1. 1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing 100730, China
  • Received:2017-07-12 Published:2017-10-01
  • Corresponding author: Wenli Yang
  • About author:
    Corresponding author: Yang Wenli, Email:
引用本文:

沈琳, 杨文利, 李栋军, 王子杨, 陈伟, 赵琦, 李逸丰, 崔蕊. 常规超声与彩色多普勒及超声造影在视网膜下出血诊断中的应用价值[J]. 中华医学超声杂志(电子版), 2017, 14(10): 730-733.

Lin Shen, Wenli Yang, Dongjun Li, Ziyang Wang, Wei Chen, Qi Zhao, Yifeng Li, Rui Cui. Diagnostic value of conventional ultrasound, color Doppler ultrasonography and contrast-enhanced ultrasound in sub-retinal hemorrhage[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2017, 14(10): 730-733.

目的

探讨常规超声、彩色多普勒及超声造影在视网膜下出血诊断中的应用价值。

方法

选取2015年1月至2016年12月在首都医科大学附属北京同仁医院就诊的怀疑视网膜下出血患者26例(26只眼),行常规超声、彩色多普勒及超声造影检查,记录病史、常规超声、彩色多普勒及超声造影表现,并通过χ2检验分析3种超声检查法在视网膜下出血的检出率。所有患者均经临床治疗及随诊确诊为视网膜下出血。

结果

26例(26只眼)常规超声可探及球壁占位性病变,平均基底径(5.31±2.21)mm,平均高度(1.97±0.98)mm。病变位置:其中,22例(22只眼,84.6%)位于后极部球壁,2例(2只眼,7.7%)位于赤道部球壁,2例(2只眼,7.7%)位于周边部球壁。病变形态:其中,7例(7只眼,26.9%)呈半球形,10例(10只眼,38.5%)呈扁平形,9例(9只眼,34.6%)为不规则形。病变内回声:12例(12只眼,46.2%)内回声均匀呈中低回声,14例(14只眼,53.8%)内回声不均匀。病变界限:17例(17只眼,65.4%)边界清晰,9例(9只眼,34.6%)边界不清。继发改变:6例(6只眼,23.1%)伴有视网膜脱离,玻璃体内均可探及不同程度的弱点状回声。23例(23只眼,88.5%)病变表面探及血流信号,病变内部无血流信号。所有病变均可见表面造影剂填充,而病变内部无造影剂填充。彩色多普勒与超声造影对视网膜下出血检出率显著高于常规超声(57.7% vs 88.5%,57.7% vs 100%),差异均有统计学意义(χ2=4.543、5.334,P均<0.01)。

结论

彩色多普勒与超声造影对视网膜下出血的临床诊断价值高于常规超声,其中超声造影具备更高的应用价值。

Objective

To explore the value of conventional ultrasound, color Doppler ultrasound and contrast-enhanced ultrasound (CEUS) in the diagnosis of sub-retinal hemorrhage.

Methods

A total of 26 patients with sub-retinal hemorrhage were examined by conventional ultrasound, color Doppler ultrasound and CEUS. The results of medical history, ultrasound, color Doppler ultrasound and CEUS were recorded and analyzed. And the difference of the detection rate between the three methods was analyzed by χ2 test.

Results

The mean fundus diameter of the sub-retinal hemorrhage was (5.31±2.21) mm, and the mean height was (1.97±0.98) mm. In twenty-two eyes (84.6%) the lesions were located in the posterior pole of the ocular wall, while in two eyes (7.7%) the lesions were located in the equator and peripheral of the ocular wall. Seven eyes (26.9%) had dome-shaped mass, ten eyes (38.5%) had flat-shaped mass, and nine eyes (34.9%) had irregular-shaped mass. The echogenecity of the lesions was homogeneous in twelve eyes (46.2%), and heterogeneous in fourteen eyes (53.8%). The lesions showed clear margin in seventeen eyes (65.4%). Blood flow signals can be detected in twenty-three eyes (88.5%). The surface of the lesions was filled by contrast-medium in all cases. The detection rate of sub-retinal hemorrhage with color Doppler and contrast-enhanced ultrasound was higher than that of conventional ultrasound, and the difference was statistically significant.

Conclusion

Color Doppler ultrasonography and CEUS can provide a powerful basis for the clinical diagnosis of sub-retinal hemorrhage, while CEUS has higher application value.

图4~6 患者,女,64岁,左眼突然视力下降1月余。图4常规超声:玻璃体内弱点状回声(积血),不规则隆起病变,内回声不均匀,边界清晰,病变表面可见带状回声(视网膜脱离);图5彩色多普勒血流成像:带状回声上可见血流信号,病变内部无血流信号;图6超声造影:带状回声上见造影剂填充,病变内部无造影剂填充
[1]
杨文利,李栋军,魏文斌. 超声造影剂时间-强度曲线在眼内肿瘤诊断与鉴别诊断的应用 [J]. 中华眼底病杂志, 2012, 28(6):569-572.
[2]
Hochman MA, Seery CM, Zarbin MA. Pathophysiology and management of subretinal hemorrhage [J]. Surv Ophthalmol, 1997, 42(3):195-213.
[3]
Choi YJ, Hyun J, Choi KS, et a1. Bullous hemorrhagic retinal detachment because of massive subretinal hemorrhagein patients with age-related maeular degeneration [J]. Retina, 2013, 33(7):1365-1374.
[4]
Coppens G, Spielberg L, Leys A. Polypoidal choroidal vasculopathy, diagnosis and management [J]. Bull Soc Belge Ophtalmol, 2011, (317):39-44.
[5]
文峰,张熊泽. 提高对视网膜出血的分类及临床意义的认识 [J]. 眼科, 2009, 18(4):221-224.
[6]
丛春霞,林锦缦,王兰惠, 等. 自发性视网膜下大量出血七例的临床和病理学观察 [J]. 中华眼科杂志, 2014, 50(10):737-742.
[7]
李超,孔德兰,卢娜, 等. 彩色多普勒在脉络膜血管瘤诊断中的应用 [J]. 中国实用眼科杂志, 2005, 23(12):1317-1319.
[8]
Cheung CM, Chee SP. Posterior scleritis in children: clinical features andtreatment [J]. Ophthalmology, 2012, 119(1):59-65.
[9]
Phillips P, Gardner E. Contrast-agent detection and quantification [J]. EBr Radiol, 2004, 14 Suppl 8:P4-P10.
[10]
李栋军,王燕霞,杨文利, 等. 超声造影在眼部占位疾病诊断的应用 [J]. 眼科, 2010, 19(4):240-243.
[11]
佘海澄,李栋军,杨文利, 等. 脉络膜血管瘤的超声造影特征 [J]. 中华实验眼科杂志, 2015, 33(1):51-54.
[12]
Hou J, Tao Y, Li XX, et al. Clinical charactersistics of polypoidal choroidal vasculopathy in Chinese patients [J]. Graefes Arch Clin Exp Ophthalmol, 2001, 249(7):975-979.
[13]
Nakashizuka H, Mitsumata M, Okisaka S, et al. Clinicopathologic findings in polypoidal choroidal vasculopathy [J]. Invest Ophthalmol Vis Sci, 2008, 49(11):4729-4737.
[14]
Kuroiwa S, Tateiwa H, Hisatomi T, et al. Pathologial features of surgically excised polypoidal choroidal vasculopathy membranes [J]. Clin Exp Ophthalmol, 2004, 32(3):297-302.
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