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中华医学超声杂志（电子版）

中华医学超声杂志（电子版） ›› 2018, Vol. 15 ›› Issue (08) : 625 -628. doi: 10.3877/cma.j.issn.1672-6448.2018.08.013

所属专题： 文献；

介入超声影像学

超声引导下经皮注射聚桂醇治疗腹、盆腔囊性病变的临床研究
李晓红1,†(), 严继萍2, 王军1, 苏卉1, 袁佩华1, 巩媛媛1   
  1. 1. 030006　山西省煤炭中心医院超声科
    2. 030012　山西省人民医院超声科
  • 收稿日期:2018-07-04 出版日期:2018-08-01
  • 通信作者: 李晓红

Ultrasound-guided percutaneous lauromacrogol injection therapy for abdominal and pelvic cystic lesions

Xiaohong Li1,†(), Jiping Yan2, Jun Wang1, Hui Su1, Peihua Yuan1, Yuanyuan Gong1   

  1. 1. Department of Ultrasound, Shanxi Coal Center Hospital, Taiyuan 030006, China
    2. Department of Ultrasound, Shanxi Provincial People′s Hospital, Taiyuan 030012, China
  • Received:2018-07-04 Published:2018-08-01
  • Corresponding author: Xiaohong Li
  • About author:
    Corresponding author: Li Xiaohong, Email:
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李晓红, 严继萍, 王军, 苏卉, 袁佩华, 巩媛媛. 超声引导下经皮注射聚桂醇治疗腹、盆腔囊性病变的临床研究[J]. 中华医学超声杂志（电子版）, 2018, 15(08): 625-628.

Xiaohong Li, Jiping Yan, Jun Wang, Hui Su, Peihua Yuan, Yuanyuan Gong. Ultrasound-guided percutaneous lauromacrogol injection therapy for abdominal and pelvic cystic lesions[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2018, 15(08): 625-628.

目的

探讨超声引导下经皮聚桂醇治疗不同大小腹、盆腔囊性病变的治疗疗效及其安全性。

方法

选取2012年12月至2014年12月在山西煤炭中心医院就诊的腹、盆腔囊性病变患者76例，其中肝囊肿23例、肾囊肿16例、卵巢巧克力囊肿23例、子宫切除术后淋巴囊肿8例及盆腔包裹性积液6例。所有患者均行超声引导下腹、盆腔囊性病变聚桂醇硬化剂治疗。按病变大小分为囊肿最大径≥8 cm组（29例）与囊肿最大径<8 cm组（47例）。同时观察治疗的不良反应及安全性。治疗后3个月、6个月及12个月超声随访观察治疗疗效，囊肿完全消失为治愈，囊肿较治疗前体积缩小程度大于75%但未完全消失为有效。

结果

聚桂醇治疗腹、盆腔囊性病变效果明显，治疗后3个月及6个月治疗总有效率分别达96.1%及100%；治疗后12个月治愈率达100%。治疗后3个月及6个月，囊肿最大径<8 cm组疗效明显优于囊肿最大径≥8 cm组（χ2=18.86、9.80，P均<0.01）。2组间不良反应发生率无显著差异（P=0.893）。

结论

超声引导下经皮聚桂醇治疗腹、盆腔囊性病变简便易行，疗效显著，安全性好，不良反应少；对于囊肿病变较大者，长期疗效也较为理想，值得临床推广应用。

关键词: 超声引导, 囊性病变, 聚桂醇, 硬化治疗
Objective

To assess the therapeutic effects and safety of ultrasound-guided percutaneous lauromacrogol injection therapy for abdominal and pelvic cystic lesions with different sizes.

Methods

Twenty-three cases of hepatic cysts, 16 cases of renal cysts, 23 cases of endometrial cysts of the ovary, 8 cases of lymphatic cysts after uterectomy and 6 cases of pelvic fluid collections were included in this study. All the patients were treated at the Shanxi Coal Center Hospital from December 2012 to December 2014 using ultrasound-guided percutaneous sclerosing lauromacrogol injection therapy. The lesions were grouped as a cyst diameter≥8 cm group and a cyst diameter<8 cm group. The side effects and safety were observed. The therapeutic effects was observed and evaluated using conventional ultrasound 3, 6 and 12 months after treatment. The cyst was considered cured if it completely disappeared and effective if it shrank more than 75% in volume but did not completely disappeared.

Results

The therapeutic effects of sclerosing lauromacrogol injection therapy for abdominal and pelvic cystic lesions were significant, with a total effective rate of 96.1% and 100%, respectively, at 3 and 6 months after treatment. The cure rate was 100% at 12 months after treatment. The therapeutic effects at 3 and 6 months for the cyst diameter<8 cm group were significantly higher than those for the cyst diameter≥8 cm group (P<0.01). The rates of adverse effects had no significant difference between the two groups (P<0.01).

Conclusion

Ultrasound-guided percutaneous lauromacrogol injection therapy for abdominal and pelvic cystic lesions is a simple, convenient, feasible, and effective method with little side effects.

Key words: Ultrasound-guided, Cystic lesions, Lauromacrogol, Sclerotheraphy
图1 肾囊肿超声引导下聚桂醇治疗前后对比图像。图1a为治疗前常规超声显示左肾囊肿，最大径8.5 cm；图1b为聚桂醇治疗后3个月超声显示囊肿完全消失
表1 76例囊性病变患者超声引导下聚桂醇治疗后疗效比较（例）
组别 例数 治疗后3个月 治疗后6个月 治疗后12个月
治愈 有效 无效 治愈 有效 无效 治愈 有效 无效
囊肿最大径≥8 cm组 29 12 14 3 18 11 0 29 0 0
囊肿最大径<8 cm组 47 41 6 0 43 4 0 47 0 0
χ2值 ? 18.86 9.80 ? ? ?
P值 ? 0.000 0.002 ? ? ?
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