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中华医学超声杂志(电子版) ›› 2019, Vol. 16 ›› Issue (12) : 931 -936. doi: 10.3877/cma.j.issn.1672-6448.2019.12.009

所属专题: 文献

心血管超声影像学

成人冠状动脉瘘的超声心动图与CT血管造影影像学特征及诊断效能分析
郭芳琪1, 刁宗平1, 王文文2, 季秀凤1, 赵佳琦1,()   
  1. 1. 200003 上海,海军军医大学附属长征医院超声诊断科
    2. 200003 上海,海军军医大学附属长征医院影像科
  • 收稿日期:2019-04-10 出版日期:2019-12-01
  • 通信作者: 赵佳琦
  • 基金资助:
    国家自然科学基金(81501492)

Echocardiography and computed tomography angiography for diagnosing coronary artery fistula in adults: imaging features and diagnostic efficacy

Fangqi Guo1, Zongping Diao1, Wenwen Wang2, Xiufeng Ji1, Jiaqi Zhao1,()   

  1. 1. Department of Ultrasound, Changzheng Hospital Affiliated to Naval Military Medical University, Shanghai 200003, China
    2. Department of Radiology, Changzheng Hospital Affiliated to Naval Military Medical University, Shanghai 200003, China
  • Received:2019-04-10 Published:2019-12-01
  • Corresponding author: Jiaqi Zhao
  • About author:
    Corresponding author: Zhao Jiaqi, Email:
引用本文:

郭芳琪, 刁宗平, 王文文, 季秀凤, 赵佳琦. 成人冠状动脉瘘的超声心动图与CT血管造影影像学特征及诊断效能分析[J]. 中华医学超声杂志(电子版), 2019, 16(12): 931-936.

Fangqi Guo, Zongping Diao, Wenwen Wang, Xiufeng Ji, Jiaqi Zhao. Echocardiography and computed tomography angiography for diagnosing coronary artery fistula in adults: imaging features and diagnostic efficacy[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2019, 16(12): 931-936.

目的

分析成人冠状动脉瘘的超声心动图以及冠状动脉CT血管造影(CTA)表现特征,并探讨超声心动图与冠状动脉CTA对成人冠状动脉瘘的诊断价值。

方法

回顾性选取2011年1月至2018年12月于海军军医大学附属长征医院就诊的疑似冠状动脉瘘患者30例。所有患者均行经胸超声心动图和冠状动脉CTA检查,并最终经手术或冠状动脉造影确诊。以手术结果或冠状动脉造影检查作为"金标准",最终确诊冠状动脉瘘患者23例,非冠状动脉瘘患者7例。分析23例冠状动脉瘘患者的超声心动图和冠状动脉CTA表现特征,并对超声心动图和冠状动脉CTA诊断冠状动脉瘘的效能进行比较分析。

结果

23例冠状动脉瘘患者中,超声心动图准确诊断20例,漏诊3例,其中2例为左冠状动脉-肺动脉瘘,1例为右冠状动脉-右心室瘘;冠状动脉CTA准确诊断22例,漏诊1例为左冠状动脉-肺动脉瘘。以手术结果或冠状动脉造影为"金标准",超声心动图诊断冠状动脉瘘的敏感度、特异度、阳性预测值、阴性预测值和准确性分别为86.96%、71.43%、90.90%、62.50%、83.33%;冠状动脉CTA诊断冠状动脉瘘的敏感度、特异度、阳性预测值、阴性预测值和准确性分别为95.65%、85.71%、95.65%、85.71%、93.33%。超声心动图与CTA这2种方法的诊断结果分别与"金标准"比较,一致性均较高,Kappa值分别为0.757、0.911(P均<0.001)。

结论

冠状动脉CTA和超声心动图2种影像学检查方法各有优势,对冠状动脉瘘均具有较好的诊断价值,可为冠状动脉瘘的诊断提供有效和可靠的信息和参考依据。

Objective

To analyze the imaging characteristics and diagnostic value of echocardiography and computed tomography angiography (CTA) in coronary artery fistula in adults.

Methods

Thirty patients with suspected coronary artery fistula admitted to Changzheng Hospital Affiliated to Naval Medical University from January 2011 to December 2018 were retrospectively selected. All patients underwent transthoracic echocardiography and CTA, and were eventually diagnosed by surgery or coronary angiography. Twenty-three patients with coronary artery fistula and seven patients with non-coronary artery fistula were diagnosed based on surgical exploration or coronary angiography. The efficacy of echocardiography and CTA in the diagnosis of coronary artery fistula was analyzed and compared.

Results

Of the 23 patients with coronary artery fistula, 20 were accurately diagnosed by echocardiography and 3 had a misdiagnosis, of whom 2 were misdiagnosed as having left coronary artery-pulmonary artery fistula, and 1 was misdiagnosed as having right coronary artery-right ventricular fistula. Of the 23 patients with coronary artery fistula, 22 were accurately diagnosed by coronary CTA, and 1 was misdiagnosed with left coronary artery-pulmonary artery fistula. Taking surgical results or coronary angiography as the "gold standard", the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of echocardiography for diagnosing coronary artery fistula were 86.96%, 71.43%, 90.90%, 62.50%, and 83.33%, respectively; the corresponding percentages of coronary CTA were 95.65%, 85.71%, 95.65%, 85.71%, and 93.33%, respectively. Both methods had a good consistency with the gold standard (κ1=0.757, P<0.001; κ2=0.911, P<0.001).

Conclusion

Both echocardiography and CTA are of good value for the diagnosis of coronary artery fistula, and can provide effective and reliable information for the diagnosis of this disease.

图1 冠状动脉瘘超声心动图表现。图a~c为右冠状动脉-右心房瘘,其中图a为大动脉短轴切面(绿色箭头所示为右冠状动脉起始部瘤样扩张;红色箭头所示为向右心房膨出并可见明显缺口),图b为彩色多普勒血流可见一粗大的五彩血流束引流入右心房(箭头所示),图c为频谱多普勒探及以舒张期为主的连续性血流频谱,左向右分流,血流速度约4.7 m/s,瞬间峰值压差约88 mmHg(1 mmHg=0.133 kPa);图d~f为右冠状动脉-右心室瘘,其中图d为左心室长轴切面显示右冠状动脉起始部内径明显扩张,呈瘤样改变,图e为心尖四腔心切面显示右心室内探及红色为主的异常血流束,走形扭曲,沿室间隔进入右心室(箭头所示),图f为频谱多普勒探及连续性频谱,血流速度最高达1.7 m/s;图g~i为左冠状动脉-肺动脉瘘,其中图g为大动脉短轴切面显示左冠状动脉起始部明显扩张,图h为舒张期可见肺动脉主干外侧紧靠肺动脉瓣处一异常蓝色血流注入,开口于肺动脉瓣下(箭头所示),图i为收缩期可见肺动脉干外侧紧靠肺动脉瓣处花色瘘口血流
图2 冠状动脉瘘的CT血管造影表现。图a~b为左冠状动脉-右心房瘘,其中图a为CT容积再现图像显示左冠状动脉起始部瘤样扩张延长,迂曲走行(箭头所示),图b为最大密度投影图像显示左冠状动脉增粗、膨大,末端与右心房异常相通(红色箭头所示为左冠状动脉起始部,绿色箭头所示为右心房);图c~d为左冠状动脉-肺动脉瘘,其中图c为CT容积再现及横轴位图像显示源于左前降支近段见一分支迂曲向上走形,匍匐在肺动脉主干表面,局部呈结节状膨大并凸起(箭头所示),图d为最大密度投影图像显示75%R-R间期时相的横轴位图像可见肺动脉内造影剂"喷射征"(箭头所示)
表1 超声心动图与冠状动脉CTA对冠状动脉瘘的诊断结果分析(例)
表2 超声心动图与冠状动脉CTA对冠状动脉瘘的诊断效能分析(%)
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