Characterization of small liver metastasis with contrast-enhanced ultrasonography

doi:10.3877/cma.j.issn.1672-6448.2016.02.011

Abstract

Abstract:

Objective

To characterize the features of small liver metastasis with contrast-enhanced ultrasound (CEUS).

Methods

Ninty-four small liver metastasis and 150 small hepatocellular carcinoma (HCC) in Zhongshan Hospital were analyzed on CEUS. Enhancement patterns, the time to enhancement, time to peak, time to isoechogenity and time to hypoechogenity were compared between small liver metastasis and HCC.

Results

Ninty-four small liver metastasis showed total enhancement and rim-like enhancement at arterial phase, and the incidences were 66.0% (62/94) and 34.0% (32/94), respectively. One hundred and fifty small HCC showed total enhancement and rim-like enhancement at arterial phase, and the incidences were 98.7% (148/150) and 1.3% (2/150), respectively. Small liver metastasis had a significantly higher proportion of rim-like enhancement than that of small HCC (P<0.01). The time to isoechogenity, time to hypoechogenity and time from isoechogenity to hypoechogenity of small liver metastasis were shorter than those of small HCC, which were (28.7±6.3) s, (39.1±16.2) s, (8.1±8.5) s and (35.8±12.5) s, (86.8±45.5) s, (52.5±44.2) s, respectively (t=-8.722, -12.636 and -10.571, all P<0.01).

Conclusions

Both of the total and rim-like enhancement are common enhancement patterns of small liver metastasis in CEUS. Both of enhancement pattern and washout time are useful in differential diagnosis of small liver metastases and small HCC. CEUS can help to diagnose small liver metastasis.

Key words: Ultrasonography, Contrast media, Liver neoplasms, Neoplasms metastasis

Xiaolong Zhang, Wenping Wang, Yi Dong, Beijian Huang, Qing Lu, Feng Mao. Characterization of small liver metastasis with contrast-enhanced ultrasonography[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2016, 13(02): 134-138.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2016.02.011

https://chaosheng.cma-cmc.com.cn/EN/Y2016/V13/I02/134

Figures/Tables 3

References 14

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组别	病灶个数	开始增强时间	达峰时间	等回声时间	低回声时间	等回声至低回声时间
转移性小肝癌	94	18.2±4.4	22.9±5.6	28.7±6.3	39.1±16.2	8.2±8.5
小HCC	150	17.6±4.6	23.0±5.6	35.8±12.5	86.8±45.5	52.5±44.2
t值	?	0.940	-0.196	-8.722	-12.636	-10.571
P值	?	>0.05	>0.05	<0.01	<0.01	<0.01

组别	病灶个数	开始增强时间	达峰时间	等回声时间	低回声时间	等回声至低回声时间
转移性小肝癌	94	18.2±4.4	22.9±5.6	28.7±6.3	39.1±16.2	8.2±8.5
小HCC	150	17.6±4.6	23.0±5.6	35.8±12.5	86.8±45.5	52.5±44.2
t值	?	0.940	-0.196	-8.722	-12.636	-10.571
P值	?	>0.05	>0.05	<0.01	<0.01	<0.01

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