Diagnostic value of ultrasonic elastosonography in choroidal melanoma

doi:10.3877/cma.j.issn.1672-6448.2017.10.004

Chinese Journal of Medical Ultrasound (Electronic Edition) ›› 2017, Vol. 14 ›› Issue (10): 734-737. doi: 10.3877/cma.j.issn.1672-6448.2017.10.004

Special Issue: ；

• Superficial Parts Ultrasound • Previous Articles Next Articles

Diagnostic value of ultrasonic elastosonography in choroidal melanoma

Wei Chen¹, Wenli Yang¹^,^†(), Dongjun Li¹, Ziyang Wang¹, Qi Zhao¹, Yifeng Li¹, Rui Cui¹, Lin Shen¹

^1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing 100730, China

Received:2017-07-27 Online:2017-10-01 Published:2017-10-01
Contact: Wenli Yang
About author:
Corresponding author: Yang Wenli, Email: yangwl_tr@163.com

Abstract

Abstract:

Objective

To explore the diagnostic value of ultrasonic elastography in choroidal melanoma.

Methods

A total of 96 cases (97 eyes) of choroidal melanoma were included in present study from June 2016 to June 2017 in Eye Center of Beijing Tongren Hospital, Capital Medical University. The control group consisted of 18 patients with choroidal hemangioma (18 eyes). All eyes were examined by color Doppler ultrasound and ultrasonic elastosonography. The strain ratio of the tumor and surrounding normal tissue was calculated for each case. By comparing the strain ratio between choroidal melanoma and choroidal hemangioma, the diagnostic value of ultrasound elastography in choroidal melanoma was investigated.

Results

The strain ratios of the two groups were 39.51±15.79 for choroidal melanoma and 13.15±10.40 for choroidal hemangioma. The independent sample t-test was performed between the two sets of data. The difference of the strain ratio between choroidal melanoma and choroidal hemangioma was statistically significant (t=6.802, P<0.001).

Conclusions

The stiffness of ocular malignant tumor (choroidal melanoma) is significantly higher than that in intraocular benign tumor (choroidal hemangioma). Ultrasonic elastography can be used as an important examination for the diagnosis and differential diagnosis of choroidal melanoma.

Key words: Choroidal melanoma, Choroidal hemangioma, Strain ratio, Ultrasonic elastosonography

Wei Chen, Wenli Yang, Dongjun Li, Ziyang Wang, Qi Zhao, Yifeng Li, Rui Cui, Lin Shen. Diagnostic value of ultrasonic elastosonography in choroidal melanoma[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2017, 14(10): 734-737.

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References 21

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