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Chinese Journal of Medical Ultrasound (Electronic Edition) ›› 2020, Vol. 17 ›› Issue (11): 1142-1144. doi: 10.3877/cma.j.issn.1672-6448.2020.11.016

Special Issue:

• Interventional Ultrasound • Previous Articles     Next Articles

Application value of ultrasound-guided needle biopsy in diagnosis of non-mass breast lesions

Chuanghua Chen1, Jianhua Fang1,(), Chenke Xu1, Wei Wang1, Fanlei Kong1, Hong Sun1   

  1. 1. Department of Ultrasound, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
  • Received:2020-02-15 Online:2020-11-01 Published:2020-11-01
  • Contact: Jianhua Fang
  • About author:
    Corresponding author: Fang Jianhua, Email:

Abstract:

Objective

To assess the diagnostic value of ultrasound-guided needle biopsy in non-mass breast lesions.

Methods

Ninety-three patients with 93 non-mass breast lesions that were classified as Breast Imaging Report and Data System (BI-RADS) 4a and above at the Department of Ultrasound, Hangzhou First People's Hospital were selected from January 2017 to December 2018. All lesions underwent ultrasound-guided needle biopsy and were confirmed by surgical pathology. The fourfold table was used to assess the diagnostic value of ultrasound-guided needle biopsy in non-mass breast lesions.

Results

The surgical pathology results showed that there were 47 malignant lesions and 46 benign lesions. In contrast, the results of ultrasound-guided needle biopsy showed 43 malignant lesions and 50 benign lesions. Four malignant lesions were missed by biopsy, which were classified as BI-RADS 4b by ultrasound but finally confirmed as ductal carcinoma in situ in three cases and invasive carcinoma in one case by surgical pathology. The sensitivity of ultrasound-guided needle biopsy was 91.4% (43/47), the specificity was 100% (46/46), the false negative rate was 8.6% (4/47), and the diagnostic accuracy rate was 95.7% (89/93).

Conclusion

Although ultrasound-guided needle biopsy has a certain false negative rate in the diagnosis of non-mass breast lesions, it has appreciated diagnostic value with regard to a relatively high specificity, sensitivity, and diagnostic accuracy rate.

Key words: Breast diseases, Ultrasonography, interventional, Biopsy, needle

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