Efficacy of ultrasound-guided pingyangmycin sclerotherapy in treatment of placental implantation

doi:10.3877/cma.j.issn.1672-6448.2021.09.008

Abstract

Abstract:

Objective

To evaluate the efficacy of ultrasound-guided pingyangmycin sclerotherapy for placenta accreta.

Methods

Twelve patients after childbirth were diagnosed with placenta accrete by color Doppler ultrasound and MRI at our hospital from January 2014 to October 2017. The efficacy of methotrexate was not satisfactory. Pingyangmycin was injected into the implanted placenta under the guidance of abdominal ultrasound. Then, the changes of human chorionic gonadotropin (HCG) in the blood, placental volume, and postoperative complications were observed.

Results

The HCG in the blood of the 12 patients were negative (21±11) days post sclerotherapy, with a decline rate of (99.95±0.07)%. The placental volume reduction rate was (59.59±8.18)%, and the implanted placenta had a relatively clear boundary with the uterine muscular wall. Three patients developed low fever 1-2 days post sclerotherapy. The thickness of the endometrium was about 0.5-0.8 cm about 1 week post curettage, and menstrual cramp occurred (32±13) days after curettage.

Conclusion

Ultrasound-guided Pingyangmycin sclerotherapy can effectively assist in the treatment of placental implantation.

Key words: Placenta accreta, Ultrasound guidance, Pingyangmycin

Junfeng Zhao, Linxue Qian, Xiaoqu Tan, Yujiang Liu. Efficacy of ultrasound-guided pingyangmycin sclerotherapy in treatment of placental implantation[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2021, 18(09): 858-861.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2021.09.008

https://chaosheng.cma-cmc.com.cn/EN/Y2021/V18/I09/858

Figures/Tables 4

References 15

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项目	平阳霉素注入第1次（共12例）	平阳霉素注入第2次（共12例）	平阳霉素注入第3次（共12例）	平阳霉素注入第4次（共5例）
血人绒毛膜促性腺激素下降率	55.98±22.15	82.13±13.11	98.33±0.68	99.95±0.07
胎盘植入体积缩小率	19.55±5.57	43.52±9.16	48.11±13.67	59.59±8.18

项目	平阳霉素注入第1次（共12例）	平阳霉素注入第2次（共12例）	平阳霉素注入第3次（共12例）	平阳霉素注入第4次（共5例）
血人绒毛膜促性腺激素下降率	55.98±22.15	82.13±13.11	98.33±0.68	99.95±0.07
胎盘植入体积缩小率	19.55±5.57	43.52±9.16	48.11±13.67	59.59±8.18

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