Evaluation of cardiovascular systemic function in uraemia patients by wave intensity

doi:10.3877/cma.j.jssn.2095-5820.2016.05.009

Abstract

Abstract:

Objective

To investigate the clinical value of wave intensity technique in evaluating cardiovascular system function in uraemia patients.

Methods

Thirty patients with uraemia (uraemia group) in Renal Department of Internal Medicine and 30 healthy individuals (normal control group) in Health examination center underwent examination by wave intensity in this study in Affiliated Hospital of North Sichuan Medical College from January 2014 to June. Cardiac function and arterial elasticity parameters were evaluated by this technology. The following heart parameters were obtained, including instantaneous acceleration wave intensity (W1), instantaneous deceleration wave intensity (W2), negative wave area (NA), the time between electrocardiogram R wave apex and W1 wave apex (R-W1) and internal time between W1-W2 wave (W1-W2). And the arterial elasticity parameters were stiffness parameter (β), elastic coefficient (Ερ), pulse wave velocity (PWVβ), compliance (AC) and argumentation index (AI). At the same time LVDd, IVS, LVPWT and LVEF were measured by M-mode ultrasonography in left ventricular long-axis view. KVMI was calculated. Independent samples t-test was used to compare the changes of WI curve parameters in uraemia group and normal control group.

Results

In uraemia group LVDd, LVPWT, LVMI, W1, W2, NA, β, Ερ and PWVβ were significantly higher than those in the normal control group [(52.23±6.25) mm vs (44.20±2.20) mm, (10.67±1.45) mm vs (8.90±1.06) mm, (177034.05±44729.42) g/m² vs (97542.50±15278.82) g/m², (15.14±8.76) mmHg?m/s³ vs (6.75±4.13) mmHg?m/s³, (1 mmHg=0.133 kPa), (3.55±2.92) mmHg?m/s³ vs (1.53±1.00) mmHg?m/s³, (78.28±58.08) mmHg?m/s² vs (41.10±24.47) mmHg?m/s², 9.35±4.13 vs 5.98±1.53, (146.66±74.06) kPa vs (75.72±19.63) kPa, (7.16±1.60) m/s vs (5.41±0.66) m/s, (t=6.638, 5.393, 9.211, 4.900, 3.703, 3.274, 4.334, 5.237, 5.718, all P<0.05)], but W1-W2 was markedly decreased [(237.03±23.72) ms vs (278±50.94) ms, t=-4.165, P<0.05)]. However, there were no significant differences between two groups for R-W1, AC, IVS, AI [(102.28±13.98) ms vs (113.69±32.71) ms, (0.86±0.37) mm²/kPa vs (0.88±0.23) mm²/kPa, (11.30±1.88) mm vs (8.97±1.40) mm, 15.13±10.85 vs 15.08±28.54, t=-1.814, -0.251, 5.453, 0.010, all P>0.05].

Conclusion

Wave intensity technique can noninvasively detect cardiac function, peripheral resistance, as well as elasticity of artery, and can also provide important clinical information for progress and intervention treatment of uraemia.

Key words: Ultrasonography, Uraemia, Heart, Arteries

Xiaoyan Zheng, Peng Gu, Ying Tang, Ling Li, Peng He. Evaluation of cardiovascular systemic function in uraemia patients by wave intensity[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2016, 13(05): 366-370.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.jssn.2095-5820.2016.05.009

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Figures/Tables 3

References 12

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组别	例数	平均年龄（岁）	肌酐（μmol/L）	心率（次/min）	收缩压（mmHg）	舒张压（mmHg）	体表面积（m²）
尿毒症组	30	47.27±12.65	885.84±337.134	82.58±13.86	154.36±23.01	91.06±13.02	1.59±0.16
健康对照组	30	43.27±10.93	62.38±14.44	67.45±11.90	114.18±9.54	79.15±7.43	1.64±0.13
t值	?	1.375	12.422	4.754	9.265	4.562	-1.155
P值	?	>0.05	<0.05	<0.05	<0.05	<0.05	<0.05
组别	例数	LVEF	LVDd（mm）	IVS（mm）	LVPWT（mm）	LVMI
尿毒症组	30	60.35±9.54	52.23±6.25	11.30±1.88	10.67±1.45	177 034.05±44 729.42
健康对照组	30	63.5±3.88	44.20±2.20	8.97±1.40	8.90±1.06	97 542.50±15 278.82
t值	?	1.788	6.638	5.453	5.393	9.211
P值	?	>0.05	<0.05	>0.05	<0.05	<0.05

组别	例数	平均年龄（岁）	肌酐（μmol/L）	心率（次/min）	收缩压（mmHg）	舒张压（mmHg）	体表面积（m²）
尿毒症组	30	47.27±12.65	885.84±337.134	82.58±13.86	154.36±23.01	91.06±13.02	1.59±0.16
健康对照组	30	43.27±10.93	62.38±14.44	67.45±11.90	114.18±9.54	79.15±7.43	1.64±0.13
t值	?	1.375	12.422	4.754	9.265	4.562	-1.155
P值	?	>0.05	<0.05	<0.05	<0.05	<0.05	<0.05
组别	例数	LVEF	LVDd（mm）	IVS（mm）	LVPWT（mm）	LVMI
尿毒症组	30	60.35±9.54	52.23±6.25	11.30±1.88	10.67±1.45	177 034.05±44 729.42
健康对照组	30	63.5±3.88	44.20±2.20	8.97±1.40	8.90±1.06	97 542.50±15 278.82
t值	?	1.788	6.638	5.453	5.393	9.211
P值	?	>0.05	<0.05	>0.05	<0.05	<0.05

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