Preliminary application of virtual touch tissue quantification imaging in diagnosis of IgA nephropathy

doi:10.3877/cma.j.issn.1672-6448.2015.05.013

Abstract

Abstract:

Objective

To evaluate the value of virtual touch quantization (VTQ) imaging in diagnosis of IgA nephropathy.

Methods

The clinical data of 85 patients with IgA nephropathy were analyzed, who were treated in Capital Medical University Affiliate Beijing Chaoyang Hospital from December 2013 to July 2014. The patients who was with critical condition, unable to cooperate and with other pathological types were excluded. Finally 108 kidneys of IgA nephropathy with mesangial cell hyperplasia in 54 cases were included into the study. Meanwhile 108 kidneys in 54 volunteers who took the health physical examination in our hospital were taken as healthy controls. VTQ was performed in middle part of kidney and the measurements of shear wave velocity (SWV) was recorded. The mean SWV of renal parenchyma and collecting system was compared in different groups.

Results

The mean SWV measurement of renal parenchyma and collecting system in control group were (2.13±0.13) m/s, (1.15±0.02) m/s; the results in IgA nephropathy group were (3.07±0.62) m/s, (1.12±0.29) m/s. The mean SWV of renal collecting system was lower than that of renal parenchyma (t=-14.481, P<0.001). The mean SWV of renal parenchyma and collecting system in IgA Nephropathy group was higher than that in control group (t=-54.01, P<0.001). The renal parenchyma VTQ value positively correlated with the degree of renal insufficiency for patients with chronic kidney disease (CKD) (F=798.70, P<0.001). The interlobular arterial resistance index (RI) increased gradually with CKD stage, but no statistical differences were found.

Conclusion

In terms of early diagnosis and clinical staging, VTQ technology has some diagnostic value in evaluation of renal parenchymal damage for patients with IgA nephropathy.

Key words: Ultrasonography, Kidney failure, chronic, Nephrosis, Glomerulonephritis, IGA

Xiaoning Liang, Ruijun Guo, Shuo Li, Ying Zhang, Yan Zhang, Hong Sun. Preliminary application of virtual touch tissue quantification imaging in diagnosis of IgA nephropathy[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2015, 12(07): 559-563.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2015.05.013

https://chaosheng.cma-cmc.com.cn/EN/Y2015/V12/I07/559

Figures/Tables 5

References 12

1	Woolfson RG. Renal failure in atherosclerotic renovascular disease: pathogenesis, diagnosis, and intervention[J]. Postgrad Med J, 2001, 77(904): 68-74.
2	Ophir J, Cdspedes I, Ponnekanti H, et a1. Elastography: a quantitativemethod for imaging The elasticityofbiological tissues[J]. Ultrason Imaging, 1991, 13(2): 111-134.
3	Luks AM, Johnson RJ, Swenson ER. Chronic kidney diseaseat high altitude[J]. J Am Soc Nephrol, 2008, 19(12): 2262-2271.
4	Daniel L, Saingra Y, Griorgi R, et a1. Tubular lesions determine prognosis of IgA nephropathy[J]. Am J Kidney Dis, 2000, 35(1): 13-20.
5	全国eGFR课题协作组. MDRD方程在我国慢性肾脏病患者中的改良和评估[J]. 中华肾脏杂志, 2006, 22(10): 589-595.
6	MeraJ, Uchida S, Nagase M, Clinic opathologicstudy on prognosticmarker in Iga nephropathy[J]. Nephron, 2000, 84(2): 40-48.
7	黄朝兴，徐玉兰. IgA肾病520例临床病理分析[J]. 中华肾脏病杂志, 2004, 20(1): 23-25.
8	Lee SMK, Rao VM, Franklin WA, et a1. IgA nephropathy: morphologic predictorsofprogressive renaldisease[J]. Hum Pathol, 1982, 13: 314-322.
9	Haas M. Histologic subclassification of IgA nephropathy:aclinicopathologic study Kidney Dis[J]. 1997, 29: 829-842.
10	White SL, Polkinghorne KR, Atkins RC, et a1. Comparison of the prevalence and mortality risk of CKD in Australia using the CKD Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) Study GFR estimating equations: the AusDiab (Australian Diabetes, Obesity and Lifestyle) Study[J]. Am J Kidney Dis, 2010, 55(4): 660-670.
11	Madhok R, Tapasvi C, Prasad U, et a1. Acoustic radiation force impulse imaging of the liver: measurement of the noal meanvalues of the shearing wave velocity in ahealthy liver[J]. J Clin Diagn Res, 2013, 7(1): 39-42.
12	Gallotti A, Pozzi MuceUi R. Acoustic ra出ationforce impulse (ARFI) technique in ultrasound with Virtual touchtissue quantification of the upper abdomen[J]. Radiol Med, 2010, 115(6): 889-897.

组别	例数	肾实质	肾集合系统	t值	P值
健康对照组	54	2.13±0.13	1.15±0.02	54.01	<0.01
IgA肾病	54	3.07±0.62	1.12±0.29	26.09	<0.01
t值	?	14.481	0.820	?	?
P值	?	<0.01	>0.05	?	?

组别	例数	肾实质	肾集合系统	t值	P值
健康对照组	54	2.13±0.13	1.15±0.02	54.01	<0.01
IgA肾病	54	3.07±0.62	1.12±0.29	26.09	<0.01
t值	?	14.481	0.820	?	?
P值	?	<0.01	>0.05	?	?

分期	例数	肾实质	肾集合系统	RI值
1期	10	2.10±0.17	1.02±0.29	0.67±0.02
2期	19	2.87±0.02^a	1.11±0.36	0.67±0.07^a
3期	8	3.09±0.01^ab	0.98±0.49	0.79±0.03^ab
4期	12	3.82±0.07^abc	0.96±0.26	0.77±0.04^abc
5期	5	3.87±0.02^abcd	0.88±0.45	0.85±0.04^abcd
F值	?	798.70	0.752	26.13
P值	?	<0.001	>0.05	<0.001

分期	例数	肾实质	肾集合系统	RI值
1期	10	2.10±0.17	1.02±0.29	0.67±0.02
2期	19	2.87±0.02^a	1.11±0.36	0.67±0.07^a
3期	8	3.09±0.01^ab	0.98±0.49	0.79±0.03^ab
4期	12	3.82±0.07^abc	0.96±0.26	0.77±0.04^abc
5期	5	3.87±0.02^abcd	0.88±0.45	0.85±0.04^abcd
F值	?	798.70	0.752	26.13
P值	?	<0.001	>0.05	<0.001

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