The value of contrast-enhanced ultrasound combined with ultrasound elastography scores in differential diagnosis of breast imaging reporting and data system 3-4 breast lesions

doi:10.3877/cma.j.issn.1672-6448.2017.10.010

Abstract

Abstract:

Objective

To explore the value of contrast-enhanced ultrasound (CEUS) scores, ultrasonic elastography (UE) and their combined scores in diagnosing breast lesions of breast imaging reporting and data system (BI-RADS) 3-4.

Methods

From October 2015 to March 2016, 60 BI-RADS 3-4 solid breast masses diagnosed by conventional ultrasound underwent UE and CEUS. According to the relevant indicators, all cases were scored and proved by surgical pathology. The diagnostic sensitivity, specificity and accuracy of CEUS scores, UE and their combined scores were evaluated, and the receiver operating characteristic (ROC) curve was drawn.

Results

Twenty-nine benign and 31 malignant lesions were confirmed by pathology. The area under the ROC curve of CEUS combined with UE scores was 0.971 which was higher than that of CEUS Scores and UE alone (0.916 and 0.908, respectively). Moreover, the sensitivity, specificity and accuracy were 87.1%, 96.6% and 92.0% for CEUS combined with UE Scores, 77.4%, 93.1% and 85.0% for CEUS Scores, 74.2%, 93.1% and 83.3% for UE, respectively.

Conclusion

CEUS combined with UE scores can improve the differetial diagnostic accuracy for BI-RADS 3-4 breast lesions.

Key words: Breast lesions, Ultrasonic elastography, Contrast-enhanced ultrasound

Yutong Xu, Tingting An, Jiuwei Zhang, Xiuhua Yang. The value of contrast-enhanced ultrasound combined with ultrasound elastography scores in differential diagnosis of breast imaging reporting and data system 3-4 breast lesions[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2017, 14(10): 766-770.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2017.10.010

https://chaosheng.cma-cmc.com.cn/EN/Y2017/V14/I10/766

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References 14

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造影特征		乳腺病灶		χ²值	P值
造影特征		良性（29个）	恶性（31个）	χ²值	P值
增强顺序		?	?	?	?
?	向心性	3（10.3%）	22（70.9%）	22.656	<0.001
?	离心性或分散性	26（89.6%）	9（29.2%）	?	?
增强均匀性		?	?	?	?
?	均匀增强	23（79.4%）	8（25.8%）	17.176	<0.001
?	不均匀增强	6（20.7%）	23（74.1%）	?	?
灌注缺损		?	?	?	?
?	存在	6（20.6%）	19（61.3%）	10.162	<0.001
?	不存在	23（79.4%）	12（38.7%）	?	?
增强程度		?	?	?	?
?	高增强	8（27.6%）	20（64.5%）	8.210	0.004
?	等-低增强	21（72.4%）	11（35.5%）	?	?
周边或穿支血管		?	?	?	?
?	存在	5（17.2%）	20（64.6%）	13.777	<0.001
?	不存在	24（82.7%）	11（35.5%）	?	?
增强后肿物面积		?	?	?	?
?	无变化	27（93.1%）	10（32.3%）	23.466	<0.001
?	变大	2（6.9%）	21（67.7%）	?	?

造影特征		乳腺病灶		χ²值	P值
造影特征		良性（29个）	恶性（31个）	χ²值	P值
增强顺序		?	?	?	?
?	向心性	3（10.3%）	22（70.9%）	22.656	<0.001
?	离心性或分散性	26（89.6%）	9（29.2%）	?	?
增强均匀性		?	?	?	?
?	均匀增强	23（79.4%）	8（25.8%）	17.176	<0.001
?	不均匀增强	6（20.7%）	23（74.1%）	?	?
灌注缺损		?	?	?	?
?	存在	6（20.6%）	19（61.3%）	10.162	<0.001
?	不存在	23（79.4%）	12（38.7%）	?	?
增强程度		?	?	?	?
?	高增强	8（27.6%）	20（64.5%）	8.210	0.004
?	等-低增强	21（72.4%）	11（35.5%）	?	?
周边或穿支血管		?	?	?	?
?	存在	5（17.2%）	20（64.6%）	13.777	<0.001
?	不存在	24（82.7%）	11（35.5%）	?	?
增强后肿物面积		?	?	?	?
?	无变化	27（93.1%）	10（32.3%）	23.466	<0.001
?	变大	2（6.9%）	21（67.7%）	?	?

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