The value of contrast-enhanced ultrasound and contrast-enhanced CT in the differential diagnosis of benign and malignant gallbladder diseases

doi:10.3877/cma.j.issn.1672-6448.2018.04.004

Abstract

Abstract:

Objective

To comparatively analyze the image characteristic of contrast-enhanced ultrasound (CEUS) and contrast-enhanced computed tomography (CECT), and explore the diagnostic value of the two methods in benign and malignant lesions of gallbladder.

Methods

comparative analysis the image characteristic of CEUS and CECT, the preoperative diagnostic results of 86 cases of gallbladder diseases were confirmed by pathology.

Results

The enhancement patterns of CEUS and CECT in benign and malignant lesions of gallbladder are similar. The sensitivity, specificity and accuracy of CEUS were 77.9% (53/68), 77.8% (14/18), 77.9% (67/86), respectively. The sensitivity, specificity and accuracy of CECT were 75% (51/68), 55.6% (10/18), 70.9% (61/86), respectively. The sensitivity, specificity and accuracy of the combination of CEUS and CECT were 83.8% (57/68), 55.6% (10/18), 77.9% (67/86), respectively. The accuracy of the combination of CEUS and CECT was higher than that of CECT in the diagnosis of malignant gallbladder lesions [(53.9±10.00) s vs (35.50±6.72) s], the differences were statistically significant (t=6.729, P<0.001).

Conclusions

The enhancement patterns of CEUS and CECT in benign and malignant gallbladder lesions are similar. The combination of CEUS and CECT is helpful for improving the diagnostic accuracy of malignant gallbladder lesions. CEUS and CECT could corroborate and complement each other, and provide more valuable information for the differential diagnosis of benign and malignant gallbladder lesions.

Key words: Ultrasonography, Contrast media, Gallbladder disease

Chunlin Tang, Yanli Guo, Ping Chen, Kaixuan Chen, Ying Tan, Zhaohui Chen, Yan Wang, Qiangwei Liu, Ye Zou, Hongyue Zeng. The value of contrast-enhanced ultrasound and contrast-enhanced CT in the differential diagnosis of benign and malignant gallbladder diseases[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2018, 15(04): 251-257.

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References 15

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检查方法	敏感度	特异度	准确性
CEUS	77.9%（53/68）	77.8%（14/18）	77.9%（67/86）
CECT	75.0%（51/68）	55.6%（10/18）	70.9%（61/86）
CEUS/CECT	83.8%（57/68）	55.6%（10/18）	77.9%（67/86）

检查方法	敏感度	特异度	准确性
CEUS	77.9%（53/68）	77.8%（14/18）	77.9%（67/86）
CECT	75.0%（51/68）	55.6%（10/18）	70.9%（61/86）
CEUS/CECT	83.8%（57/68）	55.6%（10/18）	77.9%（67/86）

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