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Chinese Journal of Medical Ultrasound (Electronic Edition) ›› 2021, Vol. 18 ›› Issue (03): 285-289. doi: 10.3877/cma.j.issn.1672-6448.2021.03.008

Special Issue:

• Obstetric and Gynecologic Ultrasound • Previous Articles     Next Articles

Prenatal ultrasound diagnosis and literature analysis of fetal congenital cataract

Jiaju Guo1, Yue Qin2, Shengli Li2,()   

  1. 1. Department of Ultrasound, Shenzhen Renai Hospital, Shenzhen 518000, China
    2. Department of Ultrasound, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen 518028, China
  • Received:2019-11-20 Online:2021-03-01 Published:2021-04-23
  • Contact: Shengli Li

Abstract:

Objective

To investigate the classification of congenital cataract, and to analyze the clinical outcome of congenital cataract.

Methods

Sonographic features and clinical outcomes of four cases of congenital cataract diagnosed by prenatal ultrasound at Shenzhen Renai Hospital between January and December 2017 were analyzed.

Results

Prenatal ultrasound indicated that one of the four cases had dense echogenic structure, which was type 1. One case of type 2 presented hyperechogenic spot in the lens. The "double ring" sign was found in 2 cases, which was type 3. Three cases were isolated cataract, and of which maternal TORCH screens were negative. One case was associated with cerebellar hemorrhage and fetal anemia, and umbilical cord blood test of rubella virus (IgM) was positive after induced labor. Clinical outcomes: the pregnancy was terminated in 2 cases, 1 case refused follow-up, and 1 case died after birth due to intrauterine hypoxia.

Conclusion

Congenital cataract is an abnormal disease of lens development. Prenatal ultrasound presents dense echogenic structure, hyperechogenic spot or "double ring" sign in the lens. Combined with detailed anatomical and etiological examination, it can provide more information for prenatal consultation and early referral and intervention treatment of congenital cataract after birth.

Key words: Ultrasonography, prenatal, Congenital cataract, Etiology, Postnatal outcome

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