对比彩色多普勒血流成像（CDFI）技术与超微血管成像（SMI）技术在甲状腺乳头状癌（PTC）病灶中血管分级及血流显示率方面的差异，探讨SMI技术在甲状腺乳头状癌诊断中的应用。

选取2015年6月至2015年12月在首都医科大学附属北京朝阳医院经穿刺或手术病理证实为PTC患者50例，共61个病灶。按照Adler分级标准，CDFI与SMI技术分别观察同一病灶的血流情况，采用χ²检验比较2种技术在血管分级及血流显示率方面的差异。

CDFI技术血流模式检出病灶血管0 ~Ⅰ级33个，Ⅱ~Ⅲ级28个；SMI技术血流模式检出病灶血管0 ~Ⅰ级6个，Ⅱ~Ⅲ级55个，CDFI与SMI 2种技术对病灶血流分级的比较，差异有统计学意义（χ²=27.475，P<0.01）；CDFI技术显示50例甲状腺乳头状癌内部或周边呈点状、短棒状血流信号，5例病灶显示内部呈分支状血流信号；SMI技术显示42个病灶内部或周边呈点状、短棒状血流信号，17个病灶内部呈分支状血流信号，2种技术检验甲状腺乳头状癌血流显示情况的比较，差异有统计学意义（χ²=7.011，P<0.01）。

与传统CDFI技术相比，SMI技术具有较高血流敏感度，可清晰显示甲状腺乳头状癌病灶内微小杂乱血管，为甲状腺乳头状癌诊断提供了可靠的血管方面的依据。其血流显示率与超声造影强化方式类似，因而具有广阔的研究前景。

To compare the difference between color Doppler flow imaging (CDFI) and superb microvascular imaging (SMI) in the evaluation of vascular grading and the display rate of vascular in papillary thyroid carcinoma (PTC).

Between June 2015 and December 2015 in Beijing Chaoyang Hosptial, 50 patients with 61 thyroid nodules were detected by ultrasonography, and pathologic types were confirmed as PTC. CDFI and SMI were used to evaluation the same nodule respectively according to Adler′s grading criteria. The different flow characteristics were analyzed by the χ² test.

In CDFI, the vascular grading of 33 patients were 0 ~Ⅰ and these of 28 patients were Ⅱ~Ⅲ by CDFI. In SMI, the vascular grading of 6 patients were 0 ~Ⅰ and these of 55 patients were Ⅱ~Ⅲ by SMI. There was a significant difference between CDFI and SMI for vascular grading (χ²=27.475, P<0.01). In CDFI, 50 patients with PTC showed punctiform and rod-like flow signals, and 5 patients showed more detail internal small branches by CDFI. In SMI, 42 patients with PTC showed punctiform and rod-like flow signals, and 17 patients showed more detail internal small branches. There was a significant difference between CDFI and SMI about the display rate of vascular (χ²=7.011, P<0.01).

Compared with CDFI, SMI is highly improved blood flow sensitivity. It can provide more detail internal small branches in PTC. The characteristics of vascular distribution are similar to strengthening mode of contrast-enhanced ultrasound in PTC, therefore, SMI is worth to further research.