Clinical and ultrasound imaging features of pancreatic acinar cell carcinoma

doi:10.3877/cma.j.issn.1672-6448.2017.06.007

Abstract

Abstract:

Objective

To explore the clinical and sonographic characteristics of pancreatic acinar cell carcinoma (PACC).

Methods

The clinical data and abdominal sonographic findings of 13 cases of PACC identified with pathology were reviewed, including contrast-enhanced ultrasound (CEUS) images. There were 9 males and 4 females with the average of 53.9 years old. Symptoms included upper abdominal pain, nausea, chest distress and weight loss.

Results

The serum level of tumor maker was elevated in only 5 cases. Eight masses (61.5%) were located in the pancreatic body-tail, 4 (30.8%) in the head, the whole pancreas was involved in 1 case. The mean maximal diameter was 8.0 cm. Four lesions (30.8%) presented as solid-cystic mass. Well-defined border was showed in 6 cases (60.0%). Exophytic type was observed in 5 cases (38.5%). Pancreatic ductal dilation was seen in 3 cases (23.1%), in which 2 cases showed obstruction of common biliary duct. Liver metastasis was assessed in 4 patients (30.8%), and lymph node metastasis in 3 cases (23.1%). Vessels were invaded in 4 cases (30.8%). In 2 cases by CEUS, one showed arterial iso-enhancement, the other with strong enhancement.

Conclusion

Certain characteristic clinical and ultrasonographic features could be revealed in PACC, as a sizable, exophytic, solid-cystic and relatively hypervascular mass with well-definded border.

Key words: Ultrasonography, Pancreatic neoplasms, Carcinoma, acinar cell

Li Tan, Ke Lyu, Guangxi Zhong, Jing Zhang, Qing Zhang, Mengsu Xiao, Yang Gui, Guili Zhou, Yuxin Jiang. Clinical and ultrasound imaging features of pancreatic acinar cell carcinoma[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2017, 14(06): 428-432.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2017.06.007

https://chaosheng.cma-cmc.com.cn/EN/Y2017/V14/I06/428

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