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中华医学超声杂志(电子版) ›› 2016, Vol. 13 ›› Issue (02) : 134 -138. doi: 10.3877/cma.j.issn.1672-6448.2016.02.011

所属专题: 文献

腹部超声影像学

转移性小肝癌超声造影表现特征
张小龙1, 王文平1,(), 董怡1, 黄备建1, 陆清1, 毛枫1   
  1. 1. 200032 上海,复旦大学附属中山医院超声科 上海市影像医学研究所
  • 收稿日期:2015-08-06 出版日期:2016-02-01
  • 通信作者: 王文平
  • 基金资助:
    国家自然科学基金项目(81371577)

Characterization of small liver metastasis with contrast-enhanced ultrasonography

Xiaolong Zhang1, Wenping Wang1,(), Yi Dong1, Beijian Huang1, Qing Lu1, Feng Mao1   

  1. 1. Department of Ultrasound, Zhongshan Hospital, Fudan University; Shanghai Institute of Medical Imaging, Shanghai 200032, China
  • Received:2015-08-06 Published:2016-02-01
  • Corresponding author: Wenping Wang
  • About author:
    Corresponding author: Wang Wenping, Email:
引用本文:

张小龙, 王文平, 董怡, 黄备建, 陆清, 毛枫. 转移性小肝癌超声造影表现特征[J/OL]. 中华医学超声杂志(电子版), 2016, 13(02): 134-138.

Xiaolong Zhang, Wenping Wang, Yi Dong, Beijian Huang, Qing Lu, Feng Mao. Characterization of small liver metastasis with contrast-enhanced ultrasonography[J/OL]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2016, 13(02): 134-138.

目的

探讨转移性小肝癌的超声造影表现特征。

方法

回顾性分析复旦大学附属中山医院94个转移性小肝癌病灶及150个小肝细胞癌(HCC)病灶的超声造影图像,对比2组病灶超声造影的增强方式和时相变化(增强时间、达峰时间、等回声时间、低回声时间)。

结果

94个转移性小肝癌病灶中,66.0%(62/94)表现为整体增强,34.0%(32/94)表现为环状增强;150个小HCC病灶中,98.7%(148/150)表现为整体增强,1.3%(2/150)表现为环状增强,转移性小肝癌动脉期环状增强的比例显著高于小HCC(P<0.01)。转移性小肝癌的超声造影等回声时间、低回声时间、从等回声至低回声所经历的时间分别为(28.7±6.3)s、(39.1±16.2)s、(8.2±8.5)s;小HCC的超声造影等回声时间、低回声时间、从等回声至低回声所经历的时间分别为(35.8±12.5)s、(86.8±45.5)s、(52.5±44.2)s,转移性小肝癌的超声造影等回声时间、低回声时间及从等回声至低回声所经历的时间均短于小HCC(t=-8.722、-12.636、-10.571,P值均<0.01)。

结论

整体增强和环状增强均为转移性小肝癌的常见表现,增强方式和减退时间有助于转移性小肝癌和小HCC的鉴别,超声造影有助于转移性小肝癌的诊断。

Objective

To characterize the features of small liver metastasis with contrast-enhanced ultrasound (CEUS).

Methods

Ninty-four small liver metastasis and 150 small hepatocellular carcinoma (HCC) in Zhongshan Hospital were analyzed on CEUS. Enhancement patterns, the time to enhancement, time to peak, time to isoechogenity and time to hypoechogenity were compared between small liver metastasis and HCC.

Results

Ninty-four small liver metastasis showed total enhancement and rim-like enhancement at arterial phase, and the incidences were 66.0% (62/94) and 34.0% (32/94), respectively. One hundred and fifty small HCC showed total enhancement and rim-like enhancement at arterial phase, and the incidences were 98.7% (148/150) and 1.3% (2/150), respectively. Small liver metastasis had a significantly higher proportion of rim-like enhancement than that of small HCC (P<0.01). The time to isoechogenity, time to hypoechogenity and time from isoechogenity to hypoechogenity of small liver metastasis were shorter than those of small HCC, which were (28.7±6.3) s, (39.1±16.2) s, (8.1±8.5) s and (35.8±12.5) s, (86.8±45.5) s, (52.5±44.2) s, respectively (t=-8.722, -12.636 and -10.571, all P<0.01).

Conclusions

Both of the total and rim-like enhancement are common enhancement patterns of small liver metastasis in CEUS. Both of enhancement pattern and washout time are useful in differential diagnosis of small liver metastases and small HCC. CEUS can help to diagnose small liver metastasis.

图1 肺癌肝转移超声表现
图2 直肠癌肝转移超声表现
表1 转移性小肝癌与小HCC的超声造影时相变化(±s,s)
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