To discuss the value of the left ventricular global systolic function in patients with coronary atherosclerotic disease before and after percutaneous coronary intervention (PCI) operation by tissue automated motion tracking of mitral annular displacement (TMAD) .

Twenty-two patients (16 males and 6 females, age 39-67 years old) with coronary atherosclerotic heart disease in the department of cardiology of our hospital who were successfully undergone PCI and successfully tracked for 6 months (coronary artery stenosis≥70%, which were confirmed by coronary angiography) , and 35 normal controls (25 males and 10 females, age 33-59 years old) were enrolled in this study. After routine echocardiography, left ventricular ejection fraction (LVEF) was measured by biplane Simpson's method. Apical four-chamber, three-chamber and two-chamber two-dimensional dynamic images were stored (the images of patients with coronary atherosclerotic disease were stored before operation and at 6 months after operation) , which lasted three to five consecutive cardiac cycles. The parameters were obtained using offline Qlab 7.0 software: maximal systolic displacement (Ds) of every annulus, systolic displacement of the middle point (D-mid) , longitudinal fractional shortening (FSL) , then the mean of Ds, D-mid and FSL were calculated respectively. The parameters of TMAD between normal controls and the CAD group were compared. Correlation analysis of parameters of TMAD and LVEF were made.

Compared with normal controls, LAd, LVd, LVEDV and LVESV in CAD group increased [(3.43±0.17) cm vs (3.66±0.21) cm, (4.60±0.23) cm vs (4.89±0.43) cm, (82.51±6.22) ml vs (88.47±9.71) ml, (25.81±3.81) ml vs (38.90±7.24) ml], while LVEF [(64.75±3.43) % vs (56.41±7.17) %] decreased ( t=-3.24, -2.67, -2.60, -6.50 and 5.53, P<0.05) . At 6 months after operation, LAd, LVd, LVEDV and LVESV [(3.57±0.18) cm, (4.76±0.31) cm, (86.86±8.69) ml, (37.08±8.31) ml] decreased, while LVEF (58.85±6.19) % increased (t=2.33, 2.79, 2.48, 3.18 and -2.12, P<0.05 for all) . The mean of Ds for normal controls, CAD group before and after operation were (13.09±1.34) mm, (10.78±1.59) mm, and (13.57±1.19) mm; the mean of D-mid for normal controls, CAD group before and after operation were (13.75±1.59) mm, (11.36±2.63) mm and (14.23±1.48) mm. The mean of FSL for normal controls, CAD group before and after operation were (17.32±2.41) %, (13.56±2.52) % and (16.29±1.77) %. The mean of Ds, D-mid, and FSL signifycantly decreased in CAD group compared with those of normal controls (t=4.19, 4.47 and 4.72, P<0.05 for all) . The mean of Ds, D-mid and FSL signifycantly increased in CAD group after operation compared with those before operation (t=-7.55, -7.48 and -6.82, P<0.05 for all) . There were no significant difference between CAD group after operation and normal controls for the mean of Ds, D-mid and FSL (t=-1.47, -1.10 and -1.44, P>0.05) . There was correlation between the mean of Ds, D-mid, FSL and LVEF (r=0.72, 0.71 and 0.83, P<0.001) in CAD group after operation.

The left ventricular global systolic function was obviously improved in CAD patients after PCI operation. TMAD technology could be used for assessment of left ventricular global systolic function in CAD patients after PCI operation.