Tissue motion tracking of mitral annular displacement in evaluation on left ventricular systolic function in patients with pre-apical hypertrophic cardiomyopathy

doi:10.3877/cma.j.issn.1672-6448.2015.10.010

Abstract

Abstract:

Objective

To investigate the value of left ventricular systolic function in patients with pre-apical hypertrophic cardiomyopathy (PAHCM) by tissue motion tracking of mitral annular displacement (TMAD).

Methods

26 cases in each group of PAHCM, hypertensive left ventricular hypertrophy (HLVH) and healthy volunteers were selected respectively. All of the subjects were examined by conventional echocardiography and store two-dimensional image of corresponding section. Using biplane Simpson method to measure left ventricular end-diastolic volume (EDV), left ventricular end-systolic volume (ESV) , stroke volume(SV) and left ventricular ejection fraction (LVEF). Mitral annulus systolic peak displacement (SD) and average peak displacement of six sites in three sections were automatic measured in QLAB 9.1 workstation.

Results

Compared with the control group, the difference was statistically significant at all points of SD and the average peak displacement in PAHCM group [(10.16±1.17) mm vs (13.09±1.25) mm, (9.03±1.35) mm vs (12.45±1.61) mm, (10.25±1.07) mm vs (12.53±1.29) mm, (10.54±1.01) mm vs (12.39±1.52) mm, (9.25±1.13) mm vs (13.09±1.75) mm, (9.95±0.83) mm vs (12.35±0.94) mm, (9.86±0.39) mm vs (12.65±0.68) mm, t=-8.74, -8.98, -6.92, -5.19, -9.37, -9.74, -18.02, P<0.05]. Compared with HLVH group, the difference was statistically significant at SD of inferoseptal, posterior wall, anteroseptal, anterior wall and the average peak displacement in PAHCM group [(10.16±1.17) mm vs (8.42±1.28) mm, (10.25±1.07) mm vs (8.36±1.20) mm, (10.54±1.01) mm vs (8.84±1.08) mm, (9.95±0.83) mm vs (8.58±1.09) mm, (9.86±0.39) mm vs (8.50±0.46) mm, t= 5.10, 6.00, 5.87, 5.11, 11.48, P<0.05], and the difference at SD of lateral and inferior wall was not statistically significant [ (9.03±1.35) mm vs (8.30±1.27) mm, (9.25±1.13) mm vs (8.52±1.21) mm, t=2.25, 2.27, P>0.05]. Compared with the control group, the difference was statistically significant at all points of SD and the average peak displacement in HLVH group [ (8.42±1.28) mm vs (13.09±1.25) mm, (8.30±1.27) mm vs (12.45±1.61) mm, (8.36±1.20) mm vs (12.53±1.29) mm, (8.84±1.08) mm vs (12.39±1.52) mm, (8.52±1.21) mm vs (13.09±1.75) mm, (8.58±1.09) mm vs (12.35±0.94) mm, (8.50±0.46) mm vs (12.65±0.68) mm, t=-13.27, -10.34, -12.09, -9.71, -10.93, -13.35, -25.59, P<0.05].

Conclusion

Compared with LVEF in PAHCM patients, using TMAD to measure mitral annular systolic displacement, which reflect the changes of left ventricular systolic function, is a more simple and sensitive new method.

Key words: Echocardiography, Pre-apical hypertrophic cardiomyopathy, Mitral annular displacement, Ventricle, Left, Systolic function

Guang Song, Jing Zhang, Weidong Ren, Hui Liu, Wei Qiao. Tissue motion tracking of mitral annular displacement in evaluation on left ventricular systolic function in patients with pre-apical hypertrophic cardiomyopathy[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2015, 12(10): 786-791.

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URL: https://chaosheng.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1672-6448.2015.10.010

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References 12

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组别	例数	男/女（例）	年龄（岁）	心率（次/分）	收缩压（mmHg）	舒张压（mmHg）	LVAMDd（mm）	LVPWDd（mm）	LVEDd （mm）
PAHCM组	26	5/21	49.85±17.77	73.65±9.25	119.15±5.60^a	74.62±6.01^a	11.88±1.31^b	7.54±1.33^a	47.58±3.51
HLVH组	26	5/21	51.27±16.89	75.46±4.22	157.81±11.88^c	87.77±4.52^c	12.00±1.39^c	12.54±1.42^c	48.35±2.86
健康对照组	26	6/20	45.42±16.25	73.27±8.92	119.23±5.98	71.92±3.92	8.00±1.27	7.23±0.99	46.81±3.12
检验值	?	χ²=0.07	F=0.16	F=0.59	F=186.18	F=77.95	F=77.08	F=144.82	F=1.53
P值	?	0.93	0.92	0.56	0.001	0.001	0.001	0.001	0.22
组别	例数	EDV（ml）	ESV（ml）	SV（ml）	LVEF（%）	LAAD（mm）	E（m/s）	A（m/s）	E/A
PAHCM组	26	80.92±5.93^ab	26.38±6.17^ab	54.54±5.58^ab	67.62±6.62	37.62±4.00^a	0.70±0.31	1.04±0.24^b	0.65±0.34^b
HLVH组	26	120.58±7.27^c	40.84±9.26^c	79.79±10.22^c	66.12±7.51	39.73±3.14^c	0.72±0.33	1.10±0.26^c	0.70±0.40^c
健康对照组	26	101.08±6.26	34.27±8.40	66.81±11.34	66.00±8.70	35.96±2.58	0.73±0.25	0.61±0.14	1.20±0.27
检验值	?	F=241.23	F=21.03	F=46.88	F=0.36	F=8.55	F=0.10	F=38.86	F=20.53
P值	?	0.001	0.001	0.001	0.70	0.001	0.90	0.001	0.001

组别	例数	男/女（例）	年龄（岁）	心率（次/分）	收缩压（mmHg）	舒张压（mmHg）	LVAMDd（mm）	LVPWDd（mm）	LVEDd （mm）
PAHCM组	26	5/21	49.85±17.77	73.65±9.25	119.15±5.60^a	74.62±6.01^a	11.88±1.31^b	7.54±1.33^a	47.58±3.51
HLVH组	26	5/21	51.27±16.89	75.46±4.22	157.81±11.88^c	87.77±4.52^c	12.00±1.39^c	12.54±1.42^c	48.35±2.86
健康对照组	26	6/20	45.42±16.25	73.27±8.92	119.23±5.98	71.92±3.92	8.00±1.27	7.23±0.99	46.81±3.12
检验值	?	χ²=0.07	F=0.16	F=0.59	F=186.18	F=77.95	F=77.08	F=144.82	F=1.53
P值	?	0.93	0.92	0.56	0.001	0.001	0.001	0.001	0.22
组别	例数	EDV（ml）	ESV（ml）	SV（ml）	LVEF（%）	LAAD（mm）	E（m/s）	A（m/s）	E/A
PAHCM组	26	80.92±5.93^ab	26.38±6.17^ab	54.54±5.58^ab	67.62±6.62	37.62±4.00^a	0.70±0.31	1.04±0.24^b	0.65±0.34^b
HLVH组	26	120.58±7.27^c	40.84±9.26^c	79.79±10.22^c	66.12±7.51	39.73±3.14^c	0.72±0.33	1.10±0.26^c	0.70±0.40^c
健康对照组	26	101.08±6.26	34.27±8.40	66.81±11.34	66.00±8.70	35.96±2.58	0.73±0.25	0.61±0.14	1.20±0.27
检验值	?	F=241.23	F=21.03	F=46.88	F=0.36	F=8.55	F=0.10	F=38.86	F=20.53
P值	?	0.001	0.001	0.001	0.70	0.001	0.90	0.001	0.001

组别	心尖部四腔心切面		心尖部三腔心切面		心尖部两腔心切面		均值
组别	后间壁	侧壁	后壁	前间壁	下壁	前壁	均值
PAHCM组	10.16±1.17^ab	9.03±1.35^b	10.25±1.07a^b	10.54±1.01^ab	9.25±1.13^b	9.95±0.83^ab	9.86±0.39^ab
HLVH组	8.42±1.28^c	8.30±1.27^c	8.36±1.20^c	8.84±1.08^c	8.52±1.21^c	8.58±1.09^c	8.50±0.46^c
正常对照组	13.09±1.25	12.45±1.61	12.53±1.29	12.39±1.52	13.09±1.75	12.35±0.94	12.65±0.68
F值	94.84	71.36	80.08	54.88	80.57	102.90	417.28
P值	0.001	0.001	0.001	0.001	0.001	0.001	0.001

组别	心尖部四腔心切面		心尖部三腔心切面		心尖部两腔心切面		均值
组别	后间壁	侧壁	后壁	前间壁	下壁	前壁	均值
PAHCM组	10.16±1.17^ab	9.03±1.35^b	10.25±1.07a^b	10.54±1.01^ab	9.25±1.13^b	9.95±0.83^ab	9.86±0.39^ab
HLVH组	8.42±1.28^c	8.30±1.27^c	8.36±1.20^c	8.84±1.08^c	8.52±1.21^c	8.58±1.09^c	8.50±0.46^c
正常对照组	13.09±1.25	12.45±1.61	12.53±1.29	12.39±1.52	13.09±1.75	12.35±0.94	12.65±0.68
F值	94.84	71.36	80.08	54.88	80.57	102.90	417.28
P值	0.001	0.001	0.001	0.001	0.001	0.001	0.001

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