切换至 "中华医学电子期刊资源库"

中华医学超声杂志(电子版) ›› 2016, Vol. 13 ›› Issue (10) : 726 -730. doi: 10.3877/cma.j.issn.1672-6448.2016.10.003

所属专题: 文献

外周血管超声影像学

原发性静脉平滑肌肿瘤的多模态超声影像特征
张梅1, 黄景1, 周琛云1, 刘春乘1, 文晓蓉1,()   
  1. 1. 610041 成都,四川大学华西医院超声科
  • 收稿日期:2016-07-23 出版日期:2016-10-01
  • 通信作者: 文晓蓉

Multimodal sonographyimage characteristics of primary vein smooth muscle tumors

Mei Zhang1, Jing Huang1, Chenyun Zhou1, Chuncheng Liu1, Xiaorong Wen1,()   

  1. 1. Department of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China
  • Received:2016-07-23 Published:2016-10-01
  • Corresponding author: Xiaorong Wen
  • About author:
    Corresponding author: Wen Xiaorong, Email:
引用本文:

张梅, 黄景, 周琛云, 刘春乘, 文晓蓉. 原发性静脉平滑肌肿瘤的多模态超声影像特征[J]. 中华医学超声杂志(电子版), 2016, 13(10): 726-730.

Mei Zhang, Jing Huang, Chenyun Zhou, Chuncheng Liu, Xiaorong Wen. Multimodal sonographyimage characteristics of primary vein smooth muscle tumors[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2016, 13(10): 726-730.

目的

分析原发性静脉平滑肌肿瘤的多模态声像图特征,以提高对该类疾病的认识,减少误诊。

方法

收集2010年1月至2016年1月在四川大学华西医院就诊的经病理证实为原发性静脉肿瘤的患者9例,其中静脉平滑肌瘤6例,平滑肌肉瘤3例。采用高分辨率灰阶超声检查在横切面及纵切面显示病变部位及大小,观察受累静脉是否增粗;采用多普勒超声观察静脉病变内有无动脉血流信号;注射超声造影剂声诺维2.4 ml后观察静脉内肿块的强化模式。

结果

本组平滑肌瘤患者6例,其中前臂头静脉3例,颈外静脉2例,右侧髂内静脉平滑肌瘤经下腔静脉延伸至右心房1例。4例静脉管径增粗;全部病例管腔内弱回声充填;彩色血流成像显示3例平滑肌瘤内部可见较丰富的动脉血流信号;所有平滑肌瘤在动脉期呈均匀高增强,静脉期呈较均匀低增强。本组3例髂-股静脉平滑肌肉瘤。静脉管径增粗呈瘤样扩张;管腔内查见不均质弱回声完全性充填;肿块内部可见较丰富的动脉血流信号;肿块在动脉期呈不均匀高增强,静脉期呈不均匀低增强,2例肿块内可见片状不强化区。

结论

静脉管径增粗对原发性静脉平滑肌肿瘤有"预警"作用;肿块内动脉血流信号对静脉肿瘤的诊断有重要价值;超声造影对鉴别血栓与肿瘤有决定性意义。

Objective

To evaluate the features of primary smooth muscle tumor originating from venous system based on the multimodal ultrasonographic images, and further to enhance the understanding of this entity with less misdiagnosis.

Methods

A total of nine patients with smooth muscle tumor, who referred to our hospital between January 2010 and January 2016, were enrolled in this study. Diagnosis was made by histopathologic findings, including 6 cases of leiomyoma and 3 cases of leiomyosarcoma. High-resolution gray-scale ultrasonography was used to assess the location and size of the tumor, as well as to identify whether the involved vein dilated or not. Doppler ultrasonography was used to detect the arterial blood flow signals in the tumor. SonoVue was injected to evaluate the enhancement mode of the tumor.

Results

Among the 9 patients, there were 6 patients with leiomyoma, of which 3 cases involving cephalic vein, 2 cases involving external jugular vein and 1 case involving internal iliac vein (extend to right atrium through inferior vena cava). Hypo-echoic mass was demonstrated in all cases, and venous dilation was found in 4 cases. Abundant arterial blood flow signals were detected in 3 cases by Doppler ultrasonography. All the tumors presented with high-level of enhancement in the arterial phase and low-level enhancement in the venous phase. In addition, there were 3 patients with leiomyosarcoma involving femoral vein or iliac vein. The characteristics of leiomyosarcoma including aneurismal dilation of the involved vein, inhomogeneous mass with hypo-echoic signals, abundant arterial blood flow signals and leiomyosarcoma-liked enhancement mode. However, there were 2 patients presented with regional non-enhancement mode.

Conclusions

We concluded that venous dilation may be a useful clue for the diagnosis of primary smooth muscle tumor originating from venous system. An arterial blood flow signal is an important feature of this lesion. Ultrasonography can be utilized to differentiate between tumor and thrombus.

图1~5 患者,女,57岁,右侧髂内静脉平滑肌瘤沿髂总静脉、下腔静脉延伸至右心房多模态超声图像。图1 为灰阶超声示右侧髂内静脉及髂总静脉内肿块完全充填;图2 为灰阶超声示下腔静脉及右心房内肿块;图3 为彩色多普勒超声示右髂内静脉肿块无血流信号;图4 为超声造影动脉期右髂静脉肿块内不均匀高增强(参照周围组织);图5 为超声造影静脉期右髂静脉肿块内为不均匀低增强(参照周围组织)。
图6~10 患者,男,75岁,左侧髂-股静脉平滑肌肉瘤的多模态超声表现。图6 为灰阶超声示静脉管腔明显增粗,内见不均匀回声肿块充填,最大直径38 mm;图7 为彩色血流显像显示肿块内见较丰富的血流信号;图8 为PW提示肿块内探及低阻动脉频谱(RI:0.56);图9 为超声造影显示动脉期肿块呈不均匀高增强,肿块内部有大片无增强坏死区;图10 为超声造影显示静脉期肿块呈不均匀低增强,肿块内部有大片无增强区;PW为脉冲多普勒
[1]
Polizzi V, Pergolini A, Zampi G, et al. Intravenous leiomyomatosis extending to the heart: a multimodality imaging approach [J]. Herz, 2014, 39(6): 720-721.
[2]
Massi D, Franchi A, Alos L, et al. Primary cutaneous leiomyosarcoma: clinicopathological analysis of 36 cases [J]. Histopathology, 2010, 56(2): 251-262.
[3]
Fornaris RJ, Rivera M, Jiménez L, et al. Multimodality Evaluation of Intravenous Leiomyomatosis: A Rare, Benign but Potentially Life-Threatening Tumor [J]. Am J Case Rep, 2015, 16: 794-800.
[4]
Al-Saif OH, Sengupta B, Amr S, et al. Leiomyosarcoma of the infra-renal inferior vena cava [J]. Am J Surg, 2011, 201(2): e18-e20.
[5]
Stoleriu C, Rizas K, Gawaz M, et al. Intracaval and intracardiac leiomyomatosis of uterine origin [J]. BMJ Case Rep, 2013.
[6]
Bousquet JC, Goze A, Hassan M, et al. Leiomyosarcoma of the inferior vena cava. Ultrasonographic appearance [J]. J Ultrasound Med, 1987, 6(1): 7-12.
[7]
Perisano C, Maffulli N, Colelli P, et al. Misdiagnosis of soft tissue sarcomas of the lower limb associated with deep venous thrombosis: report of two cases and review of the literature [J]. BMC MusculoskeletDisord, 2013, 14: 64.
[8]
Ceyhan M, Danaci M, Elmali M, et al. Leiomyosarcoma of the inferior vena cava [J]. Diagn Interv Radiol, 2007, 13(3): 140-143.
[9]
Bieliuniene E, Kavaliauskiene G, Mitraite D, et al. Leiomyosarcoma of the inferior vena cava [J]. Medicina (Kaunas), 2010, 46(3): 200-203.
[10]
Hemant D, Krantikumar R, Amita J, et al. Primary leiomyosarcoma of inferior vena cava, a rare entity: Imaging features [J]. AustralasRadiol, 2001, 45(4): 448-451.
[11]
Sidhu PS, Choi BI, Nielsen MB. The EFSUMB Guidelines on the Non-hepatic Clinical Applications of Contrast Enhanced Ultrasound (CEUS): a new dawn for the escalating use of this ubiquitous technique [J]. Ultraschall Med, 2012, 33(1): 5-7.
[1] 魏淑婕, 惠品晶, 丁亚芳, 张白, 颜燕红, 周鹏, 黄亚波. 单侧颈内动脉闭塞患者行颞浅动脉-大脑中动脉搭桥术的脑血流动力学评估[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1046-1055.
[2] 杨水华, 何桂丹, 覃桂灿, 梁蒙凤, 罗艳合, 李雪芹, 唐娟松. 胎儿孤立性完全型肺静脉异位引流的超声心动图特征及高分辨率血流联合时间-空间相关成像的应用[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1061-1067.
[3] 张璇, 马宇童, 苗玉倩, 张云, 吴士文, 党晓楚, 陈颖颖, 钟兆明, 王雪娟, 胡淼, 孙岩峰, 马秀珠, 吕发勤, 寇海燕. 超声对Duchenne肌营养不良儿童膈肌功能的评价[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1068-1073.
[4] 张宝富, 俞劲, 叶菁菁, 俞建根, 马晓辉, 刘喜旺. 先天性原发隔异位型肺静脉异位引流的超声心动图诊断[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1074-1080.
[5] 朱连华, 费翔, 韩鹏, 姜波, 李楠, 罗渝昆. 高帧频超声造影在胆囊息肉样病变中的鉴别诊断价值[J]. 中华医学超声杂志(电子版), 2023, 20(09): 904-910.
[6] 张梅芳, 谭莹, 朱巧珍, 温昕, 袁鹰, 秦越, 郭洪波, 侯伶秀, 黄文兰, 彭桂艳, 李胜利. 早孕期胎儿头臀长正中矢状切面超声图像的人工智能质控研究[J]. 中华医学超声杂志(电子版), 2023, 20(09): 945-950.
[7] 陈舜, 薛恩生, 叶琴. PDCA在持续改进超声危急值管理制度中的价值[J]. 中华医学超声杂志(电子版), 2023, 20(09): 974-978.
[8] 周钰菡, 肖欢, 唐毅, 杨春江, 周娟, 朱丽容, 徐娟, 牟芳婷. 超声对儿童髋关节暂时性滑膜炎的诊断价值[J]. 中华医学超声杂志(电子版), 2023, 20(08): 795-800.
[9] 刘欢颜, 华扬, 贾凌云, 赵新宇, 刘蓓蓓. 颈内动脉闭塞病变管腔结构和血流动力学特征分析[J]. 中华医学超声杂志(电子版), 2023, 20(08): 809-815.
[10] 郏亚平, 曾书娥. 含鳞状细胞癌成分的乳腺化生性癌的超声与病理特征分析[J]. 中华医学超声杂志(电子版), 2023, 20(08): 844-848.
[11] 张丽丽, 陈莉, 余美琴, 聂小艳, 王婧玲, 刘婷. PDCA循环法在超声浅表器官亚专科建设中的应用[J]. 中华医学超声杂志(电子版), 2023, 20(07): 717-721.
[12] 黄应雄, 叶子, 蒋鹏, 詹红, 姚陈, 崔冀. 急性肠系膜静脉血栓形成致透壁性肠坏死的临床危险因素分析[J]. 中华普通外科学文献(电子版), 2023, 17(06): 413-421.
[13] 李建美, 邓静娟, 杨倩. 两种术式联合治疗肝癌合并肝硬化门静脉高压的安全性及随访评价[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 41-44.
[14] 莫闲, 杨闯. 肝硬化患者并发门静脉血栓危险因素的Meta分析[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 678-683.
[15] 刘飞, 王影新, 马骍, 辛灵, 程元甲, 刘倩, 王悦, 张军军. 不同介质腔内心电图定位技术在乳腺癌上臂输液港植入术中应用的随机对照研究[J]. 中华临床医师杂志(电子版), 2023, 17(07): 760-764.
阅读次数
全文


摘要