探讨超声造影（CEUS）在中央型肺癌伴阻塞性肺不张中的应用价值。

对2015年7月至2017年10月杭州市第一人民医院收治的36例临床病理诊断明确且超声下能显示的中央型肺癌伴肺不张患者进行CEUS检查，分析中央型肺癌开始增强时间、肺不张组织开始增强时间及两者的达峰时间及消退时间，并观察病灶的增强模式。

CEUS对所有36例患者（100%）均能很好地区分中央型肺癌和肺不张。与肺不张组织相比，32例患者（88.9%）中央型肺癌病灶呈现"慢进快出"的增强模式，4例（11.1%）呈现"快进慢出"的增强模式。18例（50.0%）表现为均匀低增强，12例（33.3%）呈不均匀低增强，4例（11.1%）呈均匀高增强，2例（5.6%）呈不均匀高增强；所有36例患者中央型肺癌病灶开始增强时间为10~15 s，32例患者（88.9%）肺不张组织增强时间为10 s内，4例患者（11.1%）肺不张组织开始增强时间为10~18 s。

CEUS能够很好区分肿瘤组织和肺不张组织，对发现隐匿在肺不张中的肿瘤具有很好的临床应用价值。

To evaluate the clinical value of contrast-enhanced ultrasonography (CEUS) in the diagnosis of central lung cancer with obstructive atelectasis.

During the period from July 2015 to October 2017, 36 central lung cancer patients with atelectasis were admitted to the First People′s Hospital of Hangzhou. All the patients were diagnosed by clinical pathology, and the lesions can be demonstrated by ultrasound. CEUS was performed on all the patients. After the examination, the time from which central lung cancer began to increase, the time at which the lungs began to inflate, and the peak and disappearance time of both were analyzed, and the enhancement pattern of the lesions were observed.

CEUS clearly distinguished central lung cancer and atelectasis in all the 36 (100%) patients. CEUS showed central lung cancer as ″slow-in and fast-out″ mode in 32 of 36 patients, and as ″fast-out and fast-in″ mode in the remaining four cases. Among all patients, 18 had uniform low enhancement, 12 had non-uniform low enhancement, 4 had uniform high enhancement, and 2 had non-uniform high enhancement. The onset enhancement time was 4-10 seconds in 32 patients, and 10-18 seconds in 4 cases. The onset enhancement time of the tumor tissue was 10-15 seconds.

CEUS can distinguish tumor tissue from atelectasis and is helpful in discovering tumor tissue hidden in atelectasis.