切换至 "中华医学电子期刊资源库"

中华医学超声杂志(电子版) ›› 2022, Vol. 19 ›› Issue (05) : 416 -421. doi: 10.3877/cma.j.issn.1672-6448.2022.05.005

妇产科超声影像学

卵巢过度刺激伴附件扭转的超声表现及结局分析
涂鹏1, 董虹美1, 唐静1, 钟春燕1, 冉素真1,()   
  1. 1. 401147 重庆市妇幼保健院超声科
  • 收稿日期:2020-06-19 出版日期:2022-05-01
  • 通信作者: 冉素真
  • 基金资助:
    重庆市技术创新与应用发展专项(cstc2019jscx-msxmX0235)

Ultrasonographic findings and outcomes of ovarian hyperstimulation syndrome with adnexal torsion

Peng Tu1, Hongmei Dong1, Jing Tang1, Chunyan Zhong1, Suzhen. Ran1,()   

  1. 1. Department of Ultrasound, Chongqing Maternal and Child Health Hospital, Chongqing 401147, China
  • Received:2020-06-19 Published:2022-05-01
  • Corresponding author: Suzhen. Ran
引用本文:

涂鹏, 董虹美, 唐静, 钟春燕, 冉素真. 卵巢过度刺激伴附件扭转的超声表现及结局分析[J]. 中华医学超声杂志(电子版), 2022, 19(05): 416-421.

Peng Tu, Hongmei Dong, Jing Tang, Chunyan Zhong, Suzhen. Ran. Ultrasonographic findings and outcomes of ovarian hyperstimulation syndrome with adnexal torsion[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2022, 19(05): 416-421.

目的

探讨卵巢过度刺激(OHSS)患者发生附件扭转的超声诊断要点。

方法

回顾性分析2016年1月至2020年4月重庆市妇幼保健院15例超声诊断为OHSS伴附件扭转患者的临床资料及超声图像特征,并随访患者后期结局,分析病例误诊原因。采用两样本配对Wilcoxon检验比较卵巢患侧和对侧的差异。

结果

15例患者中,12例手术治疗(1例误诊),3例保守观察。手术治疗者中11例确诊为附件扭转,扭转角度为180°~1080°,均为单侧发病,右侧7例(63.6%),左侧4例(36.4%);2例(18.2%)为单纯卵巢扭转,9例(81.8%)为输卵管、韧带合并卵巢扭转。3例保守观察者后期症状好转至消失。1例误诊病例为宫内合并宫外复合妊娠。附件扭转手术确诊患者超声表现主要为患侧卵巢较对侧卵巢明显增大[8.5(7.5,10.3)cm vs 5.8(4.3,7.3)cm],差异具有统计学意义(Z=-2.58,P=0.010)。扭转蒂部结构呈“漩涡征”,血流信号较对侧减少或者消失,存在盆腔积液;扭转蒂部结构的“漩涡征”可作为OHSS患者发生附件扭转的直接且特异性征象。

结论

超声特征性图像可帮助OHSS伴附件扭转的诊断,同时对卵巢活性进行初步判定;扫查过程中应结合临床病史及超声特征,避免误诊,为患者争取临床处理时间。

Objective

To explore the key points of ultrasound diagnosis of adnexal torsion (AT) in patients with ovarian hyperstimulation (OHSS).

Methods

A retrospective analysis was carried out on the clinical medical records and ultrasonic features of 15 patients diagnosed with OHSS with AT at Chongqing Maternal and Child Health Hospital from January 2016 to April 2020. Their outcomes were followed, and the causes of misdiagnosis were analyzed. The difference between the affected ovary and contralateral ovary was compared by two-sample paired Wilcoxon test.

Results

Among the 15 patients included, 12 were treated by surgery (1 case was misdiagnosed), and 3 underwent follow-up observation. Eleven of the patients treated by surgery were diagnosed with AT, with torsion angle ranging from 180° to 1080°. All of them had unilateral onset, including 7 cases (63.6%) on the right side and 4 (36.4%) on the left side. There were 2 cases (18.2%) with ovarian torsion alone, and 9 cases (81.8%) with fallopian tube, ligament, and ovarian torsion. The symptoms of 3 patients improved or disappeared after clinical follow-up observation. One case was misdiagnosed as intrauterine complicated with extrauterine pregnancy. In the patients diagnosed with AT, ultrasonography showed significant enlargement of the ovary on the affected side [8.5 (7.5, 10.3) cm vs 5.8 (4.3, 7.3) cm], the difference was statistically significant (Z=-2.58, P=0.010 ). The torsion pedicle structure showed the "vortex sign", decreased or disappeared blood flow signals, and pelvic effusion compared with the opposite side. The "vortex sign" of the torsion pedicle structure can be a direct and specific sign of AT in OHSS patients.

Conclusion

Ultrasound can be used to diagnose OHSS with AT and preliminarily judge the ovarian activity. During scanning, clinical history and ultrasonic characteristics should be combined to avoid misdiagnosis, so as to give timely clinical treatment for patients.

图1 患者取卵术后19 h、腹痛3 h,双侧卵巢及蒂扭转超声图像特征。图a为患者双侧卵巢彩色多普勒图像:双侧卵巢均增大,卵巢实质内呈取卵术后多个囊泡样结构改变;彩色多普勒可见患侧(右侧图像)卵巢血流信号较对侧减少。图b为三维超声(OmniView模式)蒂扭转长轴图像(白色箭头所示);图c为二维超声显示蒂扭转横切面“漩涡征”图像(测量键所示)
表1 患侧卵巢及对侧卵巢大小对比[cm,MQR)]
图2 不同附件扭转角度患者蒂扭转二维超声图像(测量键及箭头所示)。图a患者蒂扭转180°,显示附件区增粗的管状结构,内可见多个“小囊泡样回声”;图b患者蒂扭转360°,显示附件区包块样结构,内呈“同心圆”状;图c患者蒂扭转720°,呈“漩涡征”图像;图d患者蒂扭转900°,显示附件区包块样结构内呈“同心圆”状及部分内可见小囊泡样结构
图3 卵巢过度刺激综合征蒂扭转患者术中及病理图像。图a术中见患侧卵巢增大,患侧输卵管、卵巢外观均呈蓝紫色,扭转720°(箭头所示);图b为卵巢间质水肿、出血病理图(HE×100);图c为输卵管间质水肿、出血病理切片图(HE×100)
1
王雅琴, 杨菁, 徐望明, 等. 超促排卵后卵巢扭转五例临床分析 [J]. 中华妇产科杂志, 2012, 47(8): 612-615.
2
Spitzer D, Wirleitner B, Steiner H, et al. Adnexal torsion in pregnancy after assisted reproduction - case study and review of the literature [J]. Geburtshilfe Frauenheilkd, 2012, 72(8): 716-720.
3
Rackow BW, Patrizio P. Successful pregnancy complicated by early and late adnexal torsion after in vitro fertilization [J]. Fertil Steril, 2007, 87(3): 697.e9-12.
4
Moro F, Bolomini G, Sibal M, et al. Imaging in gynecological disease (20): clinical and ultrasound characteristics of adnexal torsion [J]. Ultrasound Obstet Gynecol, 2020, 56(6): 934-943.
5
Valsky DV, Cohen SM, Hamani Y, et al. Whirlpool sign in the diagnosis of adnexal torsion with atypical clinical presentation [J]. Ultrasound Obstet Gynecol, 2009, 34(2):239-242.
6
Rostamzadeh A, Mirfendereski S, Rezaie MJ, et al. Diagnostic efficacy of sonography for diagnosis of ovarian torsion [J]. Pak J Med Sci, 2014, 30(2): 413-416.
7
Melcer Y, Sarig-Meth T, Maymon R, et al. Similar but different: a comparison of adnexal torsion in pediatric, adolescent, and pregnant and reproductive-age women [J]. J Womens Health (Larchmt), 2016, 25(4): 391-396.
8
Asch E, Wei J, Mortele KJ, et al. Magnetic resonance imaging performance for diagnosis of ovarian torsion in pregnant women with stimulated ovaries [J]. Fertil Res Pract, 2017, 3: 13.
9
Gu X, Yang M, Liu Y, et al. The ultrasonic whirlpool sign combined with plasma d-dimer level in adnexal torsion [J]. Eur J Radiol, 2018, 109: 196-202.
10
张小莎, 罗德清, 陈欣林. 试管婴儿早孕期合并附件扭转1例 [J]. 中国产前诊断杂志(电子版), 2019, 11(4): 99-100.
11
谢忱忱, 董虹美. 38+5周孕妇卵巢囊肿蒂扭转超声表现1例 [J]. 实用妇科内分泌电子杂志, 2018, 5(33): 158.
12
张敏. 卵巢扭转的诊断及治疗进展 [J]. 海南医学, 2019, 30(21): 2828-2831.
13
张敏, 周启昌, 文烈明, 等. 漩涡征及滤泡环征诊断早期卵巢扭转 [J]. 中国医学影像技术, 2015, 31(4): 590-592.
14
Ghulmiyyah L, Nassar A, Sassine D, et al. Accuracy of pelvic ultrasound in diagnosing adnexal torsion [J]. Radiol Res Pract, 2019, 2019: 1406291.
15
顾小宁, 杨敏, 刘勇, 等. 血管蒂内血流信号超声分级联合腹痛激发-手术时间在卵巢蒂扭转时的临床意义 [J]. 中国超声医学杂志, 2017, 33(5): 450-452.
16
Ginath S, Shalev A, Ran K, et al. Differences between adnexal torsion in pregnant and nonpregnant women [J]. J Minh Invas Gyn, 2012, 19(6): 708-714.
[1] 张婉微, 秦芸芸, 蔡绮哲, 林明明, 田润雨, 金姗, 吕秀章. 心肌收缩早期延长对非ST段抬高型急性冠脉综合征患者冠状动脉严重狭窄的预测价值[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1016-1022.
[2] 任书堂, 刘晓程, 张亚东, 孙佳英, 陈萍, 周建华, 龙进, 黄云洲. 左心室辅助装置支持下单纯收缩期主动脉瓣反流的超声心动图特征[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1023-1028.
[3] 何金梅, 尹立雪, 谭静, 张文军, 王锐, 任梅, 廖明娇. 超声心肌做功技术对2型糖尿病患者潜在左心室心肌收缩功能损伤的评价[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1029-1035.
[4] 薛艳玲, 马小静, 谢姝瑞, 何俊, 夏娟, 何亚峰. 左心声学造影在急性心肌梗死合并室间隔穿孔中的应用价值[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1036-1039.
[5] 吕琦, 惠品晶, 丁亚芳, 颜燕红. 颈动脉斑块易损性的超声造影评估及与缺血性卒中的相关性研究[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1040-1045.
[6] 魏淑婕, 惠品晶, 丁亚芳, 张白, 颜燕红, 周鹏, 黄亚波. 单侧颈内动脉闭塞患者行颞浅动脉-大脑中动脉搭桥术的脑血流动力学评估[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1046-1055.
[7] 武玺宁, 欧阳云淑, 张一休, 孟华, 徐钟慧, 张培培, 吕珂. 胎儿心脏超声检查在抗SSA/Ro-SSB/La抗体阳性妊娠管理中的应用[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1056-1060.
[8] 杨水华, 何桂丹, 覃桂灿, 梁蒙凤, 罗艳合, 李雪芹, 唐娟松. 胎儿孤立性完全型肺静脉异位引流的超声心动图特征及高分辨率血流联合时间-空间相关成像的应用[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1061-1067.
[9] 张璇, 马宇童, 苗玉倩, 张云, 吴士文, 党晓楚, 陈颖颖, 钟兆明, 王雪娟, 胡淼, 孙岩峰, 马秀珠, 吕发勤, 寇海燕. 超声对Duchenne肌营养不良儿童膈肌功能的评价[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1068-1073.
[10] 张宝富, 俞劲, 叶菁菁, 俞建根, 马晓辉, 刘喜旺. 先天性原发隔异位型肺静脉异位引流的超声心动图诊断[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1074-1080.
[11] 丁雷, 罗文, 杨晓, 庞丽娜, 张佩蒂, 刘海静, 袁佳妮, 刘瑾. 高帧频超声造影在评价C-TIRADS 4-5类甲状腺结节成像特征中的应用[J]. 中华医学超声杂志(电子版), 2023, 20(09): 887-894.
[12] 张茜, 陈佳慧, 高雪萌, 赵傲雪, 黄瑛. 基于高帧频超声造影的影像组学特征鉴别诊断甲状腺结节良恶性的价值[J]. 中华医学超声杂志(电子版), 2023, 20(09): 895-903.
[13] 冯冰, 邹秋果, 梁振波, 卢艳明, 曾奕, 吴淑苗. 老年非特殊型浸润性乳腺癌超声征象与分子生物学指标的临床研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 48-51.
[14] 赵文毅, 邹冰子, 蔡冠晖, 刘永志, 温红. 超声应变力弹性成像联合MRI-DWI靶向引导穿刺在前列腺病变诊断中的应用[J]. 中华临床医师杂志(电子版), 2023, 17(9): 988-994.
[15] 薛念余, 张盛敏, 吴凌恒, 沙蕾, 童揽月, 沈崔琴, 李朝军, 杜联芳. 研究血清胆红素对2型糖尿病患者心脏结构发生改变前心肌功能的影响[J]. 中华临床医师杂志(电子版), 2023, 17(9): 1004-1009.
阅读次数
全文


摘要