切换至 "中华医学电子期刊资源库"

中华医学超声杂志(电子版) ›› 2016, Vol. 13 ›› Issue (03) : 213 -217. doi: 10.3877/cma.j.issn.1672-6448.2016.03.010

所属专题: 妇产科超声影像学 文献 妇产科超声

妇产科超声影像学

胎儿肺部肿瘤超声诊断与临床意义
王平1, 邓学东2,(), 殷林亮2   
  1. 1. 215163 江苏省苏州市高新区东渚医院超声科
    2. 215002 南京医科大学附属苏州医院 苏州市立医院超声中心
  • 收稿日期:2015-12-30 出版日期:2016-03-01
  • 通信作者: 邓学东
  • 基金资助:
    苏州市临床医学中心资助项目(Szzx201505)

Prenatal diagnosis of fetal lung masses by ultrasonography and its clinical significance

Ping Wang1, Xuedong Deng2,(), Linliang Yin2   

  1. 1. Department of Ultrasound, Dongzhu Hospital, Suzhou 215163, China
    2. Center for Medical Ultrasound, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou 215002, China
  • Received:2015-12-30 Published:2016-03-01
  • Corresponding author: Xuedong Deng
  • About author:
    Corresponding author: Deng Xuedong, Email:
引用本文:

王平, 邓学东, 殷林亮. 胎儿肺部肿瘤超声诊断与临床意义[J/OL]. 中华医学超声杂志(电子版), 2016, 13(03): 213-217.

Ping Wang, Xuedong Deng, Linliang Yin. Prenatal diagnosis of fetal lung masses by ultrasonography and its clinical significance[J/OL]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2016, 13(03): 213-217.

目的

分析胎儿肺部肿瘤超声声像图特征及临床预后。

方法

对2011年6月1日至2013年5月31日南京医科大学附属苏州医院产前超声检查发现肺部肿瘤的38例胎儿均随访至产后或引产后,与出生后CT或引产后尸检结果对照,分析胎儿肺部肿瘤产前超声声像图特征。

结果

38例肺肿瘤胎儿中产前超声显示20例为肺囊腺瘤,其中Ⅰ型4例,声像图表现为多囊样无回声区;Ⅱ型7例,声像图表现为混合性回声;Ⅲ型9例,声像图表现为增强回声。超声检查后孕妇选择终止妊娠2例,引产胎儿尸检证实均为肺囊腺瘤;6例临床随访过程中胎儿肺部肿瘤消失;11例胎儿顺产后CT检查证实为肺囊腺瘤;1例超声检查后失访。其余18例产前超声显示为隔离肺,肿瘤呈楔形高回声,边界清,彩色多普勒血流成像显示为体循环血供;超声检查后15例胎儿顺产,9例临床随访过程中隔离肺消失,6例产后CT检查证实为隔离肺,3例超声检查后失访。与产后和引产后检查结果对照,34例临床病理资料完整的肺肿瘤胎儿中产前超声正确诊断肺囊腺瘤19例(19/19),隔离肺15例(15/15)。

结论

胎儿肺部疾病产前超声可表现为各种类型的肺部肿瘤图像,早期正确诊断对胎儿预后和临床处理有重要指导意义。

Objective

To analyze the ultrasonographic features of fetal lung masses and their clinical prognosis.

Methods

There were total 38 fetuses with lung masses detected by prenatal ultrasonography in Suzhou Hospital Affiliated to Nanjing Medical University during June 1st 2011 to May 31st 2013. They were followed up to birth or induction of labor. Prenatal ultrasonographic features were analyzed by comparing to the CT examinations after birth or autopsy.

Results

Among 38 fetuses, there were 20 fetuses with cystic adenomatoid malformation (CAM) and 18 with pulmonary sequestration (PS) diagnosed by prenatal ultrasonography, and most of them were confirmed by CT after birth or autopsy. Their ultrasonogrphic characteristics and outcome were as followings. (1) Among 20 fetuses with CAM, there were 4 cases of CAM type Ⅰ, and their ultrasonography showed polycystic anechoic areas. Ultrasonography showed mixed echoic areas in 7 cases of type Ⅱ, and hyperechoic areas in 9 cases of type Ⅲ. After prenatal ultrasonography, 2 cases chose termination of pregnancy and were confirmed by autopsy. Lung masses in 6 cases disappeared gradually during follow up. Eleven cases were confirmed as CAM by CT after birth. However 1 case was missed follow-up. (2) Ultrasonography showed well-defined wedge-shaped hyper echo in 18 cases of PS, and color Doppler flow imaging (CDFI) showed that their blood supply were all from systemic circulation. Among 15 cases who underwent natural labor, masses in 9 cases disappeared during follow-up, and 6 cases were confirmed by CT after birth. The other 3 cases were missed.

Conclusions

Fetal lung masses have different ultrasonographic characteristics. Early and exact diagnosis has great significance for fetal prognosis and clinical management.

图6 胎儿隔离肺,二维超声显示左侧胸腔隔离肺(双箭头所示),彩色多普勒血流成像示腹主动脉血供(单箭头所示)
表1 38例胎儿肺部肿瘤产前超声诊断
表2 38例肺部肿瘤胎儿临床检查及随访结果(例)
[1]
李胜利. 胎儿畸形产前诊断学[M]. 北京: 人民军医出版社, 2008: 234-256.
[2]
Sanders RC. Prenatal ultrasonic detection of anomalies with a lethal or disastrous outcome [J]. Radiol Clin North Am, 1990, 28(1): 163-177.
[3]
邓学东. 产前超声诊断与鉴别诊断[M]. 北京: 人民军医出版社, 2013: 93-94.
[4]
姜小力, 邓学东, 凌晨, 等. 胎儿肺部病变产前超声表现与临床预后[J/CD]. 中华医学超声杂志:电子版, 2012, 9(7): 602-607.
[5]
Peranteau WH, Merchant AM, Hedrick HL, et al. Prenatal course and postnatal management of peripheral bronchial atresia: association with congenital cystic adenomatoid malformation of the lung [J]. Fetal Diagn Ther, 2008, 24(3): 190-196.
[6]
Mahle WT, Rychik J, Tian ZY, et al. Echocardiographic evaluation of the fetus with congenital cystic adenomatoid malformation [J]. Ultrasound Obstet Gynecol, 2000, 16(7): 620-624.
[7]
Kulkarni SS, Teoh WH, Sia AT, et al. Ruptured uterine artery pseudoaneurysm: an overlooked cause of late postpartum haemorrhage [J]. Acta Anaesthesiol Belg, 2013, 64(4): 159-162.
[8]
殷林亮, 邓学东, 唐亚奇, 等. 胎儿肺囊腺瘤畸形的超声诊断与分型[J/CD]. 中华医学超声杂志:电子版, 2012, 9(6): 529-534.
[9]
Goldstein E, Savel RH, Ruggiero M, et al. Pulmonary sequestration: an aberrant systemic blood supply demonstrated by computed tomographic angiography with 3-dimensional reconstruction [J]. Ann Thorac Surg, 2007, 84(4): 1402.
[10]
陈欣林, 张磊, 吴绪峰, 等. 超声血管增强技术诊断胎儿隔离肺 [J]. 中国介入影像与治疗学, 2009, 6(6): 545-547.
[11]
夏薇, 夏风, 刘芳, 等. 胎儿肺隔离症超声与磁共振诊断应用分析[J/CD]. 中华医学超声杂志:电子版, 2015, 12(5): 379-382.
[12]
杜燕飞, 李传亭, 滕剑波. 产前超声及磁共振成像在胎儿肺隔离症诊断中的价值探讨 [J]. 医学影像学杂志, 2014, 24(9): 1580-1582.
[13]
郑菊, 谢红宁, 李丽娟, 等. 胎儿先天性膈疝及其相关异常的产前诊断 [J]. 中华围产医学杂志, 2010, 13(2): 98-101.
[14]
高虹, 袁桂生, 杨小红.胎儿左侧膈疝合并隔离肺超声表现一例[J/CD]. 中华医学超声杂志:电子版, 2013, 10(7): 599-600.
[15]
Lopoo JB, Goldstein RB, Lipshutz GS, et al. Fetal pulmonary sequestration: a favorable congenital lung lesion [J]. Obstet Gynecol, 1999, 94(4): 567-571.
[16]
张波, 杨太珠. 胎儿隔离肺的超声诊断与分析 [J]. 中国超声医学杂志, 2010, 26(7): 658-660.
[17]
Desai S, Dusmet M, Ladas G, et a1. Secondary vascular changes in pulmonary sequestrations [J]. Histopathology, 2010, 57(1): 121-127.
[1] 戴飞, 赵博文, 潘美, 彭晓慧, 陈冉, 田园诗, 狄敏. 胎儿心脏超声定量多参数对主动脉缩窄胎儿心脏结构及功能的诊断价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(10): 950-958.
[2] 杜祖升, 赵博文, 张帧, 潘美, 彭晓慧, 陈冉, 毛彦恺. 应用二维斑点追踪成像技术评估孕周及心尖方向对中晚孕期正常胎儿左心房应变的影响[J/OL]. 中华医学超声杂志(电子版), 2024, 21(09): 843-851.
[3] 杨忠, 时敬业, 邓学东, 姜纬, 殷林亮, 潘琦, 梁泓, 马建芳, 王珍奇, 张俊, 董姗姗. 产前超声在胎儿22q11.2 微缺失综合征中的应用价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(09): 852-858.
[4] 张商迪, 赵博文, 潘美, 彭晓慧, 陈冉, 毛彦恺, 陈阳, 袁华, 陈燕. 中晚孕期胎儿心房内径定量评估心房比例失调胎儿心脏畸形的价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 785-793.
[5] 顾莉莉, 姜凡. 安徽省超声产前筛查切面图像质量现状调查情况及分析[J/OL]. 中华医学超声杂志(电子版), 2024, 21(07): 671-674.
[6] 王秋莲, 张莹, 李春敏, 徐树明, 张玉奇. 胎儿主动脉弓部梗阻伴发复杂心内畸形的产前超声诊断及漏误诊分析[J/OL]. 中华医学超声杂志(电子版), 2024, 21(07): 718-725.
[7] 曾晴, 文华轩, 袁鹰, 廖伊梅, 秦越, 罗丹丹, 梁美玲, 李胜利. 经腹二维超声评价胎儿大脑外侧裂的新参数——外侧裂平台角度[J/OL]. 中华医学超声杂志(电子版), 2024, 21(05): 454-459.
[8] 王水清, 赵博文, 潘美, 彭晓慧, 陈冉, 马明明, 狄敏. 16~40周正常胎儿左心房后间隙指数及其Z评分的定量研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(05): 460-469.
[9] 项文静, 徐燕, 茹彤, 郑明明, 顾燕, 戴晨燕, 朱湘玉, 严陈晨. 神经学超声检查在产前诊断胼胝体异常中的应用价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(05): 470-476.
[10] 罗刚, 泮思林, 孙玲玉, 李志新, 陈涛涛, 乔思波, 庞善臣. 一种新型语义网络分析模型对室间隔完整型肺动脉闭锁和危重肺动脉瓣狭窄胎儿右心发育不良程度的评价作用[J/OL]. 中华医学超声杂志(电子版), 2024, 21(04): 377-383.
[11] 张帧, 赵博文, 潘美, 彭晓慧, 陈冉, 田园诗, 陈阳. 二维斑点追踪技术评价正常中晚孕期胎儿右心房功能的初步研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(04): 384-390.
[12] 张盼盼, 赵博文, 潘美, 彭晓慧, 陈冉, 田园诗, 林仙方, 惠姗姗, 沈婷婷. 胎儿左心房后间隙指数在胎儿肺动脉瓣缺如综合征中的应用价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(04): 391-398.
[13] 王濛, 王華麟, 王鉴, 孙锟. 先天性心脏病宫内诊疗现状与展望[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(05): 481-485.
[14] 徐婷婷, 詹泳池, 王晓东, 刘兴会. 电子胎心监测结果出现正弦波形的胎母输血综合征围生期结局分析[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(04): 382-389.
[15] 吴少敏, 张世豪, 刘炳光, 李婵, 尹嘉敏, 郑昌业, 黄素然. 胎儿巨大蛛网膜囊肿并文献复习[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(04): 390-397.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?