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中华医学超声杂志(电子版) ›› 2020, Vol. 17 ›› Issue (10) : 1011 -1015. doi: 10.3877/cma.j.issn.1672-6448.2020.10.014

所属专题: 文献

小儿超声影像学

速度向量成像技术对早产儿动脉导管未闭左心房功能的评价
房亮1, 管向红1, 白春强1, 徐安娜1, 吴文瑛1,()   
  1. 1. 067000 承德医学院附属医院南区超声科
  • 收稿日期:2020-06-30 出版日期:2020-10-01
  • 通信作者: 吴文瑛
  • 基金资助:
    承德市科学技术研究与发展计划项目(201701A049)

Evaluation of left atrial function in preterm infants with patent ducuts arteriosus by vector velocity imaging

Liang Fang1, Xianghong Guan1, Chunqiang Bai1, Anna Xu1, Wenying Wu1,()   

  1. 1. Department of Ultrasound, Affiliated Hospital of Chengde Medical College, Chengde 067000, China
  • Received:2020-06-30 Published:2020-10-01
  • Corresponding author: Wenying Wu
  • About author:
    Corresponding author: Wu Wenying, Email:
引用本文:

房亮, 管向红, 白春强, 徐安娜, 吴文瑛. 速度向量成像技术对早产儿动脉导管未闭左心房功能的评价[J]. 中华医学超声杂志(电子版), 2020, 17(10): 1011-1015.

Liang Fang, Xianghong Guan, Chunqiang Bai, Anna Xu, Wenying Wu. Evaluation of left atrial function in preterm infants with patent ducuts arteriosus by vector velocity imaging[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2020, 17(10): 1011-1015.

目的

应用速度向量成像(VVI)技术评价早产儿动脉导管未闭(PDA)对左心房功能的影响。

方法

分析2017年2月至2019年7月在承德医学院附属医院出生的<37周的符合标准的122例早产儿的临床资料,于出生后3 d及1个月进行超声心动图检查,根据是否存在PDA分为对照组(40例)、PDA闭合组(cPDA组,38例)和PDA开放组(oPDA组,44例)。所有病例进行常规超声心动图检查,并应用VVI技术测量左房存储功能(LASs、LASRs)、左房管道功能(LASe、LASRe)和左房收缩功能(LASa、LASRa)参数。对3组上述各指标进行统计比较分析。

结果

新生儿出生后3 d,cPDA组和oPDA组LASs(26.0%±2.8%、25.3%±3.5%)、LASa(-17.3%±2.0%、-16.8%±2.6%)和LASRa[(-2.47±0.40)s-1、(-2.41±0.39)s-1]均低于对照组[28.2%±5.1%、-19.4%±3.4%和(-2.73±0.42)s-1](均P<0.05)。1个月后,cPDA组各参数均恢复至正常,与对照组相比差异均无统计学意义(均P>0.05),但oPDA组LASs、LASRs、LASa和LASRa仍均显著低于对照组(均P<0.05)。

结论

早产儿PDA时左房收缩及存储功能降低,随着PDA的关闭,左房功能得以改善。

Objective

To assess left atrial (LA) function in preterm infants with patent ductus arteriosus (PDA) using vector velocity imaging (VVI).

Methods

One hundred and twenty-two preterm infants (<37 gestational weeks of age) were recruited in this study, and echocardiography was performed at both 3 days and 1 month after birth. The preterm infants were divided into three groups according to PDA size and closure during follow-up: control group (40 cases), closing PDA (cPDA) group (38 cases), and open PDA (oPDA) group (44 cases). LA longitudinal global strain (S) and strain rate (SR) were recorded at different cardiac cycle. LA strain (LASs) and LA strain rate (LASRs) were measured at ventricular systole, which represented LA reservoir function, LASe and LASRe were measured at early diastole, which represented the LA conduit function, and LASa and LASRa were measured at late diastole, which represented the LA contraction function. The LA function parameters were compared among the three groups.

Results

At day 3, in the cPDA and oPDA groups, the LASs (26.0%±2.8%, 25.3%±3.5%), LASa (-17.3%±2.0%, -16.8%±2.6%), and LASRa [(-2.47±0.40) s-1, (-2.41±0.39) s-1] were all much lower than those in the control group [28.2%±5.1%, (-19.4%±3.4%) s-1, and (-2.73±0.42) s-1] (P<0.05 for all). At 1 month, the values in the cPDA group returned to normal, but in the oPDA group, LASs, LASRs, LASa, and LASRa were still significantly lower than those in the control group (P<0.05 for all).

Conclusion

VVI is a useful tool for evaluating LA function. PDA in preterm infants results in left heart volume overload and decreased LA reservoir and contraction function. The LA function might be improved after PDA closure.

图3 应用速度向量成像(VVI)技术描记心尖三腔心切面超声图
图4 左心房应变图 LASs为心室收缩期左房应变峰值,代表左房存储功能;LASe为心室舒张早期左房应变峰值,代表左房管道功能;LASa为心室舒张晚期(即心房收缩期)左房应变峰值,代表左房收缩功能
图5 左心房应变率图 LASRs为心室收缩期左房应变率峰值,代表左房存储功能;LASRe为心室舒张早期左房应变率峰值,代表左房管道功能;LASRa为心室舒张晚期(即心房收缩期)左房应变率峰值,代表左房收缩功能
表1 3组早产儿出生后3 d及1个月传统超声心动图参数比较(±s
表2 3组早产儿出生后3 d及1个月左房不同时相应变及应变率比较(±s
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