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中华医学超声杂志(电子版) ›› 2022, Vol. 19 ›› Issue (08) : 813 -817. doi: 10.3877/cma.j.issn.1672-6448.2022.08.015

腹部超声影像学

肛瘘相关黏液腺癌的临床和超声影像特征
张光晨1, 崔立莎2, 王建新1, 初银珠1, 吴长君1,()   
  1. 1. 150001 哈尔滨医科大学附属第一医院超声科
    2. 150000 哈尔滨市第一医院消化内科
  • 收稿日期:2021-01-13 出版日期:2022-08-01
  • 通信作者: 吴长君

Clinical and ultrasonographic features of mucinous adenocarcinoma arising from anal fistula

Guangchen Zhang1, Lisha Cui2, Jianxin Wang1, Yinzhu Chu1, Changjun Wu1,()   

  1. 1. Department of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
    2. Department of Gastroenterology, Harbin First Hospital, Harbin 150000, China
  • Received:2021-01-13 Published:2022-08-01
  • Corresponding author: Changjun Wu
引用本文:

张光晨, 崔立莎, 王建新, 初银珠, 吴长君. 肛瘘相关黏液腺癌的临床和超声影像特征[J]. 中华医学超声杂志(电子版), 2022, 19(08): 813-817.

Guangchen Zhang, Lisha Cui, Jianxin Wang, Yinzhu Chu, Changjun Wu. Clinical and ultrasonographic features of mucinous adenocarcinoma arising from anal fistula[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2022, 19(08): 813-817.

目的

探讨肛瘘相关黏液腺癌的临床和超声影像特征。

方法

收集2014年5月至2020年12月于哈尔滨医科大学附属第一医院经手术病理确诊为肛瘘相关黏液腺癌的患者11例。所有患者术前均接受了经直肠超声、腹股沟淋巴结超声和肠镜检查,分析所有患者的临床和超声影像特征。

结果

所有患者的血清癌胚抗原(CEA)均有不同程度的升高,范围4.26~34.8 ng/ml(正常值为0~3.4 ng/ml),平均值为(12.3±8.4)ng/ml。所有患者的超声表现均为沿瘘管生长的海绵样混合回声团块,其中4例出现了腹股沟淋巴结转移。

结论

经直肠超声对于肛瘘相关黏液腺癌的诊断具有较好的应用价值,与血清CEA相结合,可能有助于提高诊断准确性。

Objective

To investigate the clinical and ultrasonographic features of mucinous adenocarcinoma arising from anal fistula.

Methods

From May 2014 to December 2020, 11 patients with mucinous adenocarcinoma arising from anal fistula diagnosed by pathology at the First Affiliated Hospital of Harbin Medical University were collected. All patients underwent transrectal ultrasound, inguinal lymph node ultrasound, and enteroscopy before operation, and the clinical and ultrasonic image characteristics of all patients were analyzed.

Results

Serum carcinoembryonic antigen (CEA) levels in all patients increased in varying degrees, ranging from 4.26 to 34.8 ng/ml (normal value: 0 to 3.4 ng/ml), with an average value of (12.3±8.4) ng/ml. The sonographic findings of all patients were sponge-like solid-cystic masses growing along the fistula, of which four cases had inguinal lymph node metastasis.

Conclusion

Transrectal ultrasound has good value in the diagnosis of mucinous adenocarcinoma arising from anal fistula. Transrectal ultrasound combined with serum CEA may help to improve the diagnostic accuracy.

图1 肛瘘病灶大体外观示外口处可见黏液和血性分泌物(箭头所示)
图2 肛瘘病灶大体外观示外口处可见隆起型包块(箭头所示)
表1 11例肛瘘相关MA患者的临床资料和超声表现
图3 经直肠超声示病灶沿瘘管生长(白色箭头为病灶,绿色三角为瘘管)
图4 经直肠超声示病灶内见大小不等的囊性小房,呈海绵样改变(白色箭头为病灶)
图5 经直肠超声示病灶后方回声增强(白色箭头所示)
图6 经直肠超声示病灶实性部分可见丰富血流信号(白色箭头所示)
图7 误诊为肛瘘相关黏液腺癌病灶的经直肠超声图像。超声示病灶内薄而均匀的分隔(白色箭头所示)和实性部分(绿色三角所示),其中实性部分未见血流信号,术后病理证实为凝血块
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