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中华医学超声杂志(电子版) ›› 2018, Vol. 15 ›› Issue (05) : 343 -348. doi: 10.3877/cma.j.issn.1672-6448.2018.05.004

所属专题: 妇产科超声影像学 文献 妇产科超声

妇产科超声影像学

卵巢无性细胞瘤的超声表现
桂阳1, 杨萌1, 苏娜1, 齐振红1, 戴晴1, 姜玉新1,()   
  1. 1. 100730 中国医学科学院北京协和医学院 北京协和医院超声科
  • 收稿日期:2018-03-30 出版日期:2018-05-01
  • 通信作者: 姜玉新

The ultrasoundcharacteristics of ovarian dysgerminoma

Yang Gui1, Meng Yang1, Na Su1, Zhenhong Qi1, Qing Dai1, Yuxin Jiang1,()   

  1. 1. Department of Ultrasound, Pecking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
  • Received:2018-03-30 Published:2018-05-01
  • Corresponding author: Yuxin Jiang
  • About author:
    Corresponding author: Jiang Yuxin, Email:
引用本文:

桂阳, 杨萌, 苏娜, 齐振红, 戴晴, 姜玉新. 卵巢无性细胞瘤的超声表现[J]. 中华医学超声杂志(电子版), 2018, 15(05): 343-348.

Yang Gui, Meng Yang, Na Su, Zhenhong Qi, Qing Dai, Yuxin Jiang. The ultrasoundcharacteristics of ovarian dysgerminoma[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2018, 15(05): 343-348.

目的

探讨卵巢无性细胞瘤的超声声像图特征,总结诊断和鉴别诊断要点。

方法

回顾性分析2012年6月至2017年7月北京协和医院收治,经术后病理证实的21例卵巢无性细胞瘤患者22个肿瘤的超声表现及临床病理检查资料。

结果

21例卵巢无性细胞瘤患者多数(15/21)<30岁,平均年龄(25.7±9.0)岁;22个原发肿瘤体积较大,平均径线(10.6±3.6)cm,中位径线11.4 cm;超声均显示附件区实性为主、边界清晰的低回声肿物(单侧肿物20例,双侧肿物1例),部分(11/22)呈类圆形,部分(11/22)呈分叶状,内部回声不均匀,可见条索样中高回声、囊性变的无回声区或钙化成分;肿物内有较丰富的低阻血流。术前超声检查提示盆腹腔积液1例,腹膜后多发肿大淋巴结2例,术后证实转移3例。基因检查显示3例合并染色体异常。20例血清人绒毛膜促性腺激素(hCG)水平均有不同程度升高,为6.3~3800.5 IU/L。

结论

卵巢无性细胞瘤多为年轻女性患者,单侧原发病灶,超声表现为体积较大,以实性为主的低回声肿物,呈类圆形或分叶状结构,边界清晰,内部回声不均匀,可合并小无回声区及钙化灶,有较丰富的低阻血流,结合临床及血清hCG水平可做出初步诊断。

Objective

To explore the sonographic features of ovarian dysgerminoma and to evaluate the value of ultrasound in the diagnosis of ovarian dysgerminoma.

Methods

Between June 2012 and July 2017, 21 patients had surgically confirmed ovarian dysgerminoma in Pecking Union Medical College Hospital. The twenty-two lesions′ sonographic features and the Patients′ clinical characteristics were reviewed.

Results

Twenty-twoprimary lesions from 21 patients were sized 4.2-16.0 cm in meanand the median mean diameter was 11.4 cm, manifesting as well-defined mass. Half of the lesions were round (11/22) and half of the lesions were lobulated (11/22). The internal echo was mostly hypoechoic and heterogeneous, contained hyperechoic, anechoic or calcified components. Blood supplies of solid components were mainly rich with low resistance. Postoperative metastasis occurred in three cases, including one case of massive pelvic effusion and two cases of enlarged retroperitoneal lymph nodes in ultrasound. Three of them were diagnosed of chromosomal abnormalities in gene test. Elevated serum level of human chorionic gonadotropin (hCG) was observed in all patients, ranging from 6.3 to 3800.5 IU/L.

Conclusions

Patients with ovarian dysgerminoma were mainly of youth age. Ovariandysgerminoma have obvious ultrasonographic characteristics. Combined with serum hCG level, the accuracy of diagnosis could be improved.

图1~4 女性患者,20岁,盆腔巨大实性为主占位病变超声声像图及手术标本图。图1灰阶超声宽景成像示盆腔巨大低回声占位病变,呈类圆形;图2声像图示肿物内丰富条形血流;图3频谱图示瘤内低阻血流信号;图4肿物手术标本示包膜光滑,切面灰白、质中
图7,8 女性患者,31岁,盆腔巨大实性为主占位病变超声声像图。图7灰阶声像图示盆腔巨大低回声占位病变,呈分叶状,内部回声明显不均;图8彩色多普勒血流成像示肿物内粗大条形穿入血流信号
表1 21例患者22个附件区肿物超声声像图表现(个数,±s)
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