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中华医学超声杂志(电子版) ›› 2018, Vol. 15 ›› Issue (08) : 616 -619. doi: 10.3877/cma.j.issn.1672-6448.2018.08.010

所属专题: 文献

妇产科超声影像学

卵巢透明细胞癌临床与超声图像分析
刘伟1, 李长虹1, 林颖奇1, 周钦英1, 钱林学1,()   
  1. 1. 100050 首都医科大学附属北京友谊医院超声科
  • 收稿日期:2018-01-10 出版日期:2018-08-01
  • 通信作者: 钱林学

The research on clinical and ultrasonographic features of ovarian clear cell carcinoma

Wei Liu1, Changhong Li1, Yingqi Lin1, Qinying Zhou1, Linxue Qian1,()   

  1. 1. Dipatment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
  • Received:2018-01-10 Published:2018-08-01
  • Corresponding author: Linxue Qian
  • About author:
    Corresponding author: Qian Linxue, Email:
引用本文:

刘伟, 李长虹, 林颖奇, 周钦英, 钱林学. 卵巢透明细胞癌临床与超声图像分析[J]. 中华医学超声杂志(电子版), 2018, 15(08): 616-619.

Wei Liu, Changhong Li, Yingqi Lin, Qinying Zhou, Linxue Qian. The research on clinical and ultrasonographic features of ovarian clear cell carcinoma[J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2018, 15(08): 616-619.

目的

探讨卵巢透明细胞癌(OCCC)超声声像图特点,为卵巢透明细胞癌的早期诊断提供依据。

方法

对2005年1月至2017年5月经首都医科大学附属北京友谊医院临床诊治及手术病理确诊为卵巢透明细胞癌的45例患者超声声像图特点进行回顾性分析。

结果

45例卵巢透明细胞癌患者的46个病灶(单侧卵巢病灶44例,双侧卵巢病灶1例)中32个(69.6%)形态规则,14个(30.4%)形态不规则;40个(87.0%)病灶边界清晰,6个(13.0%)病灶边界不清晰。病灶最大径4.8~17.6 cm,平均(10.2±3.4)cm;其中以实性为主的病灶15个(32.6%),以囊性为主的病灶12个(26.1%),囊实混合型病灶19个(41.3%);彩色多普勒血流成像示28个(60.9%)病灶内血流信号丰富;18个(39.1%)病灶内血流信号不丰富;6例(13.3%)伴腹腔积液。

结论

卵巢透明细胞癌肿瘤病灶较大,以单侧、边界清晰、囊实性改变、血流信号丰富的病灶居多。超声检查及早发现卵巢癌病灶可为患者早期诊断和手术治疗提供依据。

Objective

To investigate the ultrasound characteristics of ovarian clear cell carcinoma (OCCC) and provide basis for early diagnosis of OCCC.

Methods

Retrospective analysis was performed on 45 patients with OCCC, who were pathologically diagnosed and treated in Beijing Friendship Hospital, Capital Medical University from January 2005 to May 2017.

Results

In forty-five cases of OCCC, forty-six lesions were found (forty-four cases of unilateral ovarian lesions, one case of bilateral ovarian lesion). Among forty-six lesions, thirty-two (69.6%) were regular in shape, fourteen (30.4%) were irregular. Among forty-six lesions, forty (87.0%) had clear margin, six (13.0%) had blurry margin. The maximum diameter of lesion was 4.8-17.6 cm with mean value of 10.2±3.4 cm. Fifteen lesions (32.6%) were predominantly solid, twelve lesions (26.1%) were cystic, and nineteen lesions (41.3%) were mixed. The color Doppler examination showed that twenty-eight (69.9%) lesions had abundant blood flow, while eighteen (39.1%) lesions had little blood flow. Ascites was found in six (13.3%) cases.

Conclusions

OCCC usually appears as a large unilateral mass with mixed component, clear margin and abundant blood flow.Ultrasound examination can play an important role in the early diagnosis of OCCC, and provide valuable information for surgical treatment.

图5,6 患者51岁,卵巢透明细胞癌(囊实混合型)术前灰阶及彩色多普勒血流成像图。图5术前经腹部超声声像图示盆腔内一巨大囊实性肿物,大小17.6 cm×9.8 cm×17.4 cm,边界清楚,囊性部分内透声差,囊腔内见多个实性团块样突起,形态不规则,右卵巢未显示;图6彩色多普勒血流成像示肿物实性部分血流信号不丰富
表1 45例卵巢透明细胞癌患者46个卵巢肿物术前超声分型表现及检查结果(个数)
1
Kennedy AW, Biscotti CV, Hart WR, et al. Ovarian clear cell adenocarcinoma [J]. Gynecol Oncol, 1989, 32(3):342-349.
2
佟晓晶,王晓彬,李联昆. 原发性卵巢透明细胞癌70例预后因素分析 [J]. 中国实用妇科与产科杂志, 2015, 31(2):153-155.
3
Matsuura Y, Robertson G, Marsden DE, et al. Thromboembolic complications in patients with clear cell carcinoma of the ovary [J]. Gynecol Oncol, 2007, 104(2):406-410.
4
吴小肄,徐洁,徐丛剑, 等. 卵巢透明细胞癌的临床特点及预后分析 [J]. 中国临床医学, 2011, 18(5):693-695.
5
马绍康,张宏图,吴令英, 等. 88例卵巢透明细胞癌临床及预后分析 [J]. 中华肿瘤杂志, 2007, 29(10):784-788.
6
朱丽莎,刘玲,邓燕杰. 卵巢透明细胞癌合并卵巢子宫内膜异位症的临床病理学分析 [J/CD]. 中华妇幼临床医学杂志(电子版), 2015, 11(1):68-72.
7
Heaps JM, Nieberg RK, Berek JS. Malignant neoplasms arising in endometriosis [J]. Obstet Gynecol, 1990, 75(6):1023-1028.
8
Pearce CL, Templeman C, Rossing MA, et al. Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies [J]. Lancet Oncol, 2012, 13(4):385-394.
9
杨莹超,王雪梅,李小平, 等. 60例卵巢透明细胞癌临床分析 [J]. 中国妇产科临床杂志, 2016, 17(6):516-518.
10
Sampson J. Endometrial carcinoma of the ovary arising in endometrial tissue in that organ [J]. Arch Surg, 1925, 10:1-2.
11
Somigliana E, Vigano′ P, Parazzini F, et al. Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence [J]. Gynecol Oncol, 2006, 101(2):331-341.
12
Penson RT, Dizon DS, Birrer MJ. Clear cell cancer of the ovary [J]. Curr Opin Oncol, 2013, 25(5):553-557.
13
Scarfone G, Bergamini A, Noli S, et al. Characteristics of clear cell ovarian cancer arising from endometriosis: a two center cohort study [J]. Gynecol Oncol, 2014, 133(3):480-484.
14
刘国艳,袁碧波,糜若然. 卵巢透明细胞癌诊治进展 [J]. 国际妇产科学杂志, 2012, 39(4):364-367; 372.
15
鲁红. 妇科超声诊断与鉴别诊断 [M]. 北京: 人民军医出版社, 2012: 288-289.
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