探讨胎儿单脐动脉产前超声表现及伴发先天异常的临床意义。

对2014年10月至2015年12月在南京医科大学附属苏州医院产前检查发现单脐动脉的121例胎儿的超声表现、合并其他异常及脐动脉缺失的侧别进行分析。

单脐动脉胎儿超声特征：（1）121例单脐动脉胎儿产前二维超声横断面扫查时膀胱周围左侧或右侧仅见1条脐动脉。（2）胎儿单脐动脉检出结果：121例单脐动脉胎儿中左侧脐动脉缺失59例（48.8%，59/121），右侧脐动脉缺失62例（51.2%，62/121），左侧与右侧单脐动脉的检出率相近。（3）合并先天异常：121例单脐动脉胎儿中合并其他先天异常16例，以心脏异常占多数（43.8%，7/16），包括室间隔缺损，法洛四联症，永存左上腔静脉，主动脉弓发育不良，右位主动脉弓，右心房、右心室增大。其中右侧脐动脉缺失胎儿合并其他先天异常的检出率（68.8%，11/16）高于左侧脐动脉缺失的胎儿（31.3%，5/16）。

单脐动脉胎儿左侧与右侧脐动脉缺失的检出率相近，但右侧脐动脉缺失合并先天异常的胎儿多于左侧脐动脉缺失的胎儿。

To discuss the absent side of a single umbilical artery (SUA) and the clinical significance of the associated anomalies which related to it.

The characteristics of the Prenatal ultrasound findings and the associated anomalies of 121 SUA fetuses which were all examined prospectively in Prental Ultrasound Center of Suzhou Municipal Hospital from October 2014 to December 2015 were studied and analyzed.

The ultrasonic features of SUA: (1) One hundred and twenty-one fetuses with SUA were diagnosed prenatally by ultrasound. There was only one umbilical artery surrounding the urinary bladder through transverse section by two-dimensional ultrasound. (2) The results of the findings of the left-absent umbilical artery and the right-absent umbilical artery: the left-absent umbilical artery was detected in 59/121 (48.8%, 59/121) fetuses, compared with right-absent umbilical artery in 62/121 (51.2%, 62/121) cases. (3) Associated with congenital anomalies: congenital anomalies were noted prenatally in 16/121 SUA fetuses and the most common abnormality was heart defects. These heart defects include ventricular septal defect, tetralogy of Fallot, persistent left superior vena cave, right-sided aortic arch, aortic dysplasia, enlarged right atrium and ventricle. Congenital anomalies were noted prenatally in 5/59 fetuses with left-absent umbilical artery and in 11/62 fetuses with right-absent umbilical artery.

In SUA fetuses, the absence of umbilical artery appears to occur equally at each side. Moreover, the relevance ratio of the right-absent umbilical artery with congenital anomalies is higher than that of the left-absent umbilical artery with congenital anomalies.