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中华医学超声杂志(电子版) ›› 2026, Vol. 23 ›› Issue (02) : 145 -150. doi: 10.3877/cma.j.issn.1672-6448.2026.02.006

妇产科超声影像学

胎儿肠管扩张的超声动态监测及其与小肠梗阻关联性和预后分析
张培培1, 张一休1,(), 武玺宁1, 欧阳云淑1, 周希亚2, 吕嬿2, 戴晴1, 孟华1,()   
  1. 1 100730 中国医学科学院北京协和医学院 北京协和医院超声医学科
    2 100730 中国医学科学院北京协和医学院 北京协和医院妇产科
  • 收稿日期:2025-11-20 出版日期:2026-02-01
  • 通信作者: 张一休, 孟华
  • 基金资助:
    中央高水平医院临床科研业务费资助(2025-PUMCH-A-016)

Dynamic ultrasound monitoring of fetal intestinal dilatation: clinical utility and correlation with postnatal obstruction and prognosis

Peipei Zhang1, Yixiu Zhang1,(), Xining Wu1, Yunshu Ouyang1, Xiya Zhou2, Yan Lyu2, Qing Dai1, Hua Meng1,()   

  1. 1 Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
    2 Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2025-11-20 Published:2026-02-01
  • Corresponding author: Yixiu Zhang, Hua Meng
引用本文:

张培培, 张一休, 武玺宁, 欧阳云淑, 周希亚, 吕嬿, 戴晴, 孟华. 胎儿肠管扩张的超声动态监测及其与小肠梗阻关联性和预后分析[J/OL]. 中华医学超声杂志(电子版), 2026, 23(02): 145-150.

Peipei Zhang, Yixiu Zhang, Xining Wu, Yunshu Ouyang, Xiya Zhou, Yan Lyu, Qing Dai, Hua Meng. Dynamic ultrasound monitoring of fetal intestinal dilatation: clinical utility and correlation with postnatal obstruction and prognosis[J/OL]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2026, 23(02): 145-150.

目的

探讨产前超声动态监测胎儿肠管扩张的临床价值,分析其与新生儿小肠梗阻的相关性,为产前咨询、预后分析提供依据。

方法

回顾性收集2019年1月至2025年8月在北京协和医院就诊或转诊的中晚孕期超声提示胎儿肠管宽度超过相应孕周第97百分位数值的病例,记录肠管扩张检出孕周、肠管扩张宽度、羊水量、腹腔积液等超声指标并随访生后结局,依据随访结果将新生儿分为小肠梗阻组和非肠道梗阻组。采用Fisher精确概率检验或Mann-Whitney U非参数检验比较组间各指标数据的差异。

结果

共纳入34例肠管扩张病例,其中22例新生儿证实小肠梗阻(小肠梗阻组),12例无梗阻(非肠道梗阻组)。小肠梗阻组肠管扩张首次检出孕周更早(P=0.036)、肠管扩张宽度更宽[2.64(1.50,5.94)mm vs 1.35(0.62,2.32)mm;Z=3.127,P=0.002],且均至少2次超声检查提示扩张。亚组分析显示,空肠闭锁病例(9例)较回肠闭锁病例(8例)更易在中孕期首次检出肠管扩张(77.8% vs 12.5%,P=0.023),且更常合并羊水过多(88.9% vs 12.5%,P=0.003)。8例合并胎粪性腹膜炎者均合并腹腔积液,其中3例出现肠管宽度一过性降低。除1例回肠闭锁患儿术后死亡外,其余患儿均预后良好。

结论

产前超声动态监测肠管扩张变化,结合检出孕周、扩张程度、羊水量及腹腔积液等指标,可有效判断胎儿是否存在小肠梗阻及梗阻部位,并早期识别胎粪性腹膜炎等并发症,对预后评估及产前咨询具有重要临床价值。

Objective

To evaluate the clinical value of dynamic prenatal ultrasonography in monitoring fetal intestinal dilatation, and to analyze its correlation with neonatal small intestinal obstruction, so as to provide evidence for prenatal counseling and prognostic evaluation.

Methods

A retrospective analysis was conducted on cases in which fetal intestinal width exceeded the 97th percentile for the corresponding gestational week as identified by mid-to-late pregnancy ultrasonography. All case were managed or referred to Peking Union Medical College Hospital from January 2019 to August 2025. Ultrasonic parameters recorded included the gestational week at initial detection of intestinal dilatation, severity of dilatation, amniotic fluid volume, and presence of abdominal effusion. Postnatal outcomes were followed up and statistically analyzed.

Results

A total of 34 cases with fetal intestinal dilatation were enrolled, of whom 22 were postnatally confirmed as neonatal small intestinal obstruction and 12 had no obstruction. Compared with the non-obstruction group, the obstruction group had an earlier gestational week at initial detection of intestinal dilatation (P=0.036) and more severe dilatation [2.64 (1.50, 5.94) mm vs 1.35 (0.62, 2.32) mm; Z=3.127, P=0.002]; moreover, intestinal dilatation was detected on at least two consecutive ultrasonographic examinations. Subgroup analysis showed that jejunal atresia was more likely than ileal atresia to present with intestinal dilatation in the second trimester (77.8% vs 12.5%, P=0.023), and was accompanied by a higher incidence of polyhydramnios (88.9% vs 12.5%, P=0.003). All 8 cases complicated by meconium peritonitis had abdominal effusion, and 3 of them showed a transient reduction of intestinal diameter. Except for one infant with ileal atresia who died after surgery, all other infants achieved a favorable prognosis.

Conclusion

Dynamic prenatal ultrasonic monitoring of fetal intestinal dilatation, combined with indicators including gestational week at detection, dilatation severity, amniotic fluid volume, and abdominal effusion, enables accurate prediction of fetal small intestinal obstruction and its location, as well as early identification of complications such as meconium peritonitis. This is of crucial clinical significance for prenatal prognosis assessment and genetic counseling.

表1 22例肠道梗阻胎儿产前及生后情况
编号 孕妇年龄(岁) 首次检出孕周(周) 最大肠管宽度(mm) 其他异常 分娩孕周
(周)
胎儿性别 胎儿出生体质量(g) 病理 生后手术时间(d) 随访时间(月)
1 25 34 21 / 38 4800 小肠梗阻 3 6
2 30 26 19 / 38 3630 小肠梗阻 2 17
3 30 25 9 / 31 900 小肠梗阻 2 28
4 30 31 29 腹腔积液、羊水多 35 2420 小肠梗阻、胎粪性腹膜炎 1 36
5 30 28 18 腹腔积液、混合回声 38 3110 小肠梗阻、胎儿胎粪性腹膜炎 1 48
6 30 30 29 腹腔少量积液、羊水多 38 2830 空肠闭锁 1 22
7 31 25 11 羊水多 36 2670 空肠闭锁 2 3
8 28 25 15 羊水多 34 1940 空肠闭锁 1 1
9 29 25 10 羊水多 37 2770 空肠闭锁 2 4
10 26 32 23 羊水多 35 2350 空肠闭锁 0.5 10
11 42 26 33 羊水多 36 2420 空肠闭锁 0.5 5
12 25 27 31 羊水多 36 2780 空肠闭锁 1 25
13 23 25 22 腹腔积液、羊水多 37 2960 空肠闭锁、胎粪性腹膜炎 0.5 13
14 32 25 32 腹腔积液、腹腔内中等回声 38 3570 空肠闭锁、胎粪性腹膜炎 2 2
15 31 29 26 / 38 3220 回肠闭锁 1 6
16 29 28 23 / 37 2980 回肠闭锁 1 7
17 36 36 35 / 40 3560 回肠闭锁 2 6
18 32 32 20 腹腔积液、腹腔内钙化 37 2280 回肠闭锁、胎粪性腹膜炎 2 11
19 32 29 26 腹腔积液、羊水多 38 3240 回肠闭锁、胎粪性腹膜炎 1 10
20 35 30 18 腹腔积液 36 2170 回肠闭锁、胎粪性腹膜炎 1 2
21 26 27 18 腹腔积液 34 1310 回肠闭锁、胎粪性腹膜炎 2 1
22 33 28 25 / 40 2550 回肠闭锁 1 1
图1 胎儿肠管宽度与中晚孕期正常胎儿肠管宽度参考值曲线对比
图2 孕27周胎儿(病例21)肠管宽度为13 mm(图a),孕29周时胎儿肠管宽度为10 mm,腹腔积液15 mm(图b),孕30周时肠管宽度为14 mm,腹腔积液6 mm(图c),孕33周时肠管宽度为18 mm,腹腔未见积液(图d),孕34周实施剖宫产,新生儿术后诊断为回肠闭锁、胎粪性腹膜炎 注:黄箭头示胎儿肠管,白箭头示胎儿腹腔积液
图3 孕25周胎儿(病例14)肠管宽度为20 mm,腹腔内强回声(图a),孕26周时胎儿肠管宽度为13 mm,腹腔积液18 mm,腹腔内强回声(图b、c),孕29周时肠管宽度为18 mm,腹腔未见积液(图d),孕34周时肠管宽度为18 mm,腹腔内强回声,腹腔未见积液(图e),孕36周时肠管宽度为24 mm,腹腔未见积液(图f)。孕38周实施剖宫产,新生儿术后诊断为空肠闭锁、胎粪性腹膜炎 注:黄箭头示胎儿肠管,白箭头示胎儿腹腔积液,绿箭头示胎儿腹腔内强回声
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